MARC

LEADER 00000cam a2200000 i 4500
001 SCIDIR_ocn123797277
003 OCoLC
005 20231117014732.0
006 m o d
007 cr |||||||||||
008 070419s2007 ne a ob 001 0 eng d
040 |a QCL  |b eng  |e pn  |c QCL  |d N$T  |d YDXCP  |d MERUC  |d E7B  |d OCLCQ  |d IDEBK  |d OCLCQ  |d OPELS  |d OCLCQ  |d OPELS  |d CUS  |d OCLCF  |d OCLCQ  |d D6H  |d INARC  |d VT2  |d OCLCA  |d UKMGB  |d LEAUB  |d WURST  |d SFB  |d OCLCQ  |d OCLCO  |d OCLCQ  |d OCLCO  |d OCL  |d OCLCQ  |d OPELS 
015 |a GBB6H3770  |2 bnb 
016 7 |a 013771828  |2 Uk 
016 7 |a 017581795  |2 Uk 
019 |a 146543036  |a 156831469  |a 441803489  |a 648303236  |a 1050958881  |a 1064526285  |a 1125727167 
020 |a 9780080489254  |q (electronic bk.) 
020 |a 0080489257  |q (electronic bk.) 
020 |a 0123740185  |q (electronic bk.) 
020 |a 9780123740182  |q (electronic bk.) 
020 |a 1281049417 
020 |a 9781281049414 
020 |a 9786611049416 
020 |a 661104941X 
035 |a (OCoLC)123797277  |z (OCoLC)146543036  |z (OCoLC)156831469  |z (OCoLC)441803489  |z (OCoLC)648303236  |z (OCoLC)1050958881  |z (OCoLC)1064526285  |z (OCoLC)1125727167 
050 4 |a RC372  |b .N48 2007eb 
060 4 |a W1  |b IN834 v.81 2007 
060 4 |a WL 385  |b N49336 2007 
072 7 |a MED  |x 032000  |2 bisacsh 
072 7 |a MED  |x 058060  |2 bisacsh 
082 0 4 |a 618.97/6853  |2 22 
245 0 4 |a The neurobiology of epilepsy and aging /  |c edited by R. Eugene Ramsay [and four others]. 
260 |a Amsterdam ;  |a Boston :  |b Academic Press,  |c �2007. 
300 |a 1 online resource (xvii, 343 pages) :  |b illustrations 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
490 1 |a International review of neurobiology ;  |v v. 81 
504 |a Includes bibliographical references and index. 
505 0 |a Cover -- Copyright Page -- Dedication Page -- Contents -- Contributors -- Acknowledgment -- Chapter 1: Epilepsy in the Elderly: Scope of the Problem -- I. Introduction -- II. Known Knowns -- A. Incidence and Prevalence of Epilepsy Is Higher in the Community-Dwelling Elderly Than in Younger Adults or Children -- B. Prevalence and Incidence of Epilepsy Is Higher Among Nursing Home Residents Than Community-Dwelling Elderly -- C. Retirement Age of 65 Is a Political Decision, Not Related to Medical Condition -- D. The Elderly Are Not a Homogeneous Group -- E. Patterns of AED Use Differ Markedly Between Countries and Between Community-Dwelling and Nursing Home Elderly -- F. In Nursing Homes, the Young-Old are More Likely to Use an AED than the Old-Old -- G. Causes of Epilepsy in the Elderly -- H. Many Seizures in the Elderly are not Epileptic -- I. AED Pharmacology Is Different in the Elderly -- J. Choosing AEDs for an Elderly Person Is Difficult -- K. Drug Interactions With Non-AEDs Are a Major Problem -- III. Known Unknowns -- IV. Unknown Unknowns -- V. Unknown Knowns -- A. The "Therapeutic" Range of Total Phenytoin is 10-20 mg/liter -- B. AED Levels Are Stable Over Time With Constant Doses -- VI. Conclusion -- References -- Chapter 2: Animal Models in Gerontology Research -- I. Animal Models in Aging Research: Considerations for Experimental Design -- II. The Age Factor -- III. Genetic Background -- IV. Choice of Strain -- V. Environmental Influences -- VI. Genomic Manipulations -- VII. Resources -- References -- Chapter 3: Animal Models of Geriatric Epilepsy -- I. Introduction -- II. Mouse Models -- A. Senescence-Accelerated Mouse -- B. Cacnb4 (lh) Mouse -- C. MTIII( -/- ) Mouse -- D. El Mouse -- E. DBA Mouse -- F. Acute Seizure Models in Common Strains -- III. Gerbil Model -- IV. Rat Models -- A. Acute Seizure Models -- B. Lesion Models -- C. Chronic Epilepsy Models -- V. Conclusions -- References -- Chapter 4: Life and Death of Neurons in The Aging Cerebral Cortex -- I. Introduction -- II. Cortical Circuitry and Alzheimer's Disease -- A. Overview -- B. Hippocampal Pathology in AD -- C. Neocortical Pathology in AD -- D. Neurofilament Protein Is a Marker of Neuronal Vulnerability in AD -- E. Summary: AD and Cortical Circuitry -- III. AAMI: Functional Decline Without Neuron Loss -- A. Introduction -- B. The Aging Cerebral Cortex: Nonhuman Primate Studies -- IV. Interactions Between Neural and Endocrine Senescence -- V. Conclusions -- Acknowledgments -- References -- Chapter 5: An In Vitro model of Stroke-Induced Epilepsy: Elucidation of the Roles of Glutamate and Calcium in the Induction and Maintenance of Stroke-Induced Epileptogenesis -- I. Introduction -- II. Role of Glutamate in the Pathophysiology of Stroke -- III. Developing an In Vitro Model of Glutamate Injury That Causes a Mixed Population of Injured and Dead Neurons in Preparations of Hippocampal Neurons in Culture -- IV. Development of SREDs in Neurons Surviving Injury -- V. Neuronal Networks Di. 
520 |a Discusses all aspects of epilepsy in aging patients. 
588 0 |a Print version record. 
546 |a English. 
650 0 |a Epilepsy in old age. 
650 0 |a Neurobiology. 
650 0 |a Older people. 
650 1 2 |a Epilepsy  |x physiopathology  |0 (DNLM)D004827Q000503 
650 2 2 |a Aged  |0 (DNLM)D000368 
650 2 |a Neurobiology  |0 (DNLM)D009446 
650 6 |a �Epilepsie chez la personne �ag�ee.  |0 (CaQQLa)201-0287494 
650 6 |a Neurobiologie.  |0 (CaQQLa)201-0010246 
650 6 |a Personnes �ag�ees.  |0 (CaQQLa)201-0005549 
650 7 |a elderly.  |2 aat  |0 (CStmoGRI)aat300025913 
650 7 |a MEDICAL  |x Geriatrics.  |2 bisacsh 
650 7 |a MEDICAL  |x Nursing  |x Gerontology.  |2 bisacsh 
650 7 |a Older people.  |2 fast  |0 (OCoLC)fst01199093 
650 7 |a Epilepsy in old age.  |2 fast  |0 (OCoLC)fst00914214 
650 7 |a Neurobiology.  |2 fast  |0 (OCoLC)fst01036315 
653 0 0 |a epilepsie 
653 0 0 |a epilepsy 
653 0 0 |a verouderen 
653 0 0 |a aging 
653 0 0 |a neurologie 
653 0 0 |a neurology 
653 0 0 |a neurofysiologie 
653 0 0 |a neurophysiology 
653 0 0 |a neurofarmacologie 
653 0 0 |a neuropharmacology 
653 0 0 |a geneeskunde 
653 0 0 |a medicine 
653 0 0 |a neurobiologie 
653 0 0 |a neurobiology 
653 1 0 |a Medicine (General) 
653 2 0 |a Neurophysiology 
653 1 0 |a Geneeskunde (algemeen) 
653 2 0 |a Neurofysiologie 
700 1 |a Ramsay, Eugene,  |e editor. 
776 0 8 |i Print version:  |t Neurobiology of epilepsy and aging.  |d Amsterdam ; Boston : Academic Press, �2007  |z 9780123740182  |z 0123740185  |w (OCoLC)130001598 
830 0 |a International review of neurobiology ;  |v v. 81. 
856 4 0 |u https://sciencedirect.uam.elogim.com/science/book/9780123740182  |z Texto completo 
856 4 0 |u https://sciencedirect.uam.elogim.com/science/bookseries/00747742  |z Texto completo 
856 4 0 |u https://sciencedirect.uam.elogim.com/science/bookseries/00747742/81  |z Texto completo