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Wnt signaling in embryonic development /
A superb compilation of reviews from leading experts in the field of Wnt signaling, volume 17 in the Advances in Developmental Biology series offers 7 chapters, each devoted to a separate area of research on Wnt signaling. Written by specialists in the field, these chapters cover different levels of...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Amsterdam ; Boston :
Elsevier,
2007.
|
| Colección: | Advances in developmental biology (Amsterdam, Netherlands) ;
v. 17. |
| Temas: | |
| Acceso en línea: | Texto completo Texto completo |
Tabla de Contenidos:
- Cover
- Front Cover
- Wnt Signaling in Embryonic Development
- Copyright Page
- Contents
- List of Contributors
- Preface
- Common principles and species differences
- Processes involved
- Pathway or network: Variations of different steps in signal transduction
- Looking ahead
- Chapter 1: Wnt/beta-catenin-mediated transcriptional regulation
- 1. Introduction
- 2. The TCF family as mediators of Wnt/beta-catenin signaling
- 3. The "Off state": Repression of Wnt targets in the absence of signaling
- 4. The "On State" in the nucleus; Arm/beta-catenin triggers the switch
- 5. beta-Catenin-mediated gene repression
- 6. Switching off signaling: A nuclear role for the destruction complex
- 7. Concluding remarks
- References
- Chapter 2: Wnt signaling and the establishment of cell polarity
- 1. Wnt-signaling pathways
- 2. Apical-basal and Planar Cell Polarity
- 3. Regulation of apical-basal polarity by Wnt signaling
- 4. PCP signaling in the Drosophila wing
- 5. PCP signaling in the Drosophila eye
- 6. PCP signaling is conserved in mammalian epithelium
- 7. Noncanonical Wnt signaling and polarized cell movements
- 8. Wnt signaling and asymmetric cell division
- 9. A new model system for PCP
- 10. Future directions
- References
- Chapter 3: Wnt signaling in C. elegans: New insights into the regulation of POP-1/TCF-mediated activation and repression
- 1. Introduction
- 2. Wnt signaling in C. elegans: Pathway components
- 3. A canonical Wnt pathway regulates Hox gene expression
- 4. Wnt/MAPK signaling
- 5. P2/EMS signaling: Spindle orientation and endoderm induction
- 6. T cell polarity
- 7. Z1/4 polarity: Axis determination in the somatic gonad
- 8. Multiple mechanisms regulate POP-1 transcriptional activity
- References
- Chapter 4: The Wnt-signaling pathways in mammalian patterning and morphogenesis
- 1. Introduction
- 2. The canonical Wnt pathway in mammalian patterning
- 3. The noncanonical Wnt pathway in mammalian morphogenesis
- 4. Summary
- References
- Chapter 5: Cell migration under control of Wnt-signaling in the vertebrate embryo
- 1. Introduction
- 2. Modes of cell migration in the vertebrate embryo
- 3. Cell migration in the early embryo
- 4. Neuronal migration
- 5. Cell migration in eye development
- 6. Heart development
- 7. Conclusions
- Acknowledgments
- References
- Chapter 6: Multiple roles for Wnt signaling in the development of the vertebrate neural crest
- 1. Introduction
- 2. Wnt signals and neural crest induction
- 3. Expression of Wnt ligands and receptors
- 4. Gain- and loss-of-function studies
- 5. Wnt signals and a hierarchy of regulatory steps
- 6. Wnt signals in delamination and the onset of migration
- 7. Wnt signals and neural crest cell fate diversification
- 8. Conclusions and future directions
- Acknowledgments
- References
- Chapter 7: Wnt pathways in angiogenesis
- 1. Angiogenesis: A brief introduction
- 2. Wnts and Frizzleds in vascular biology
- 3. Wnt signaling and pathological angiogenesis.