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Regulators and effectors of small GTPases. Ras family / Volume 407 :
The Ras superfamily (>150 human members) encompasses Ras GTPases involved in cell proliferation, Rho GTPases involved in regulating the cytoskeleton, Rab GTPases involved in membrane targeting/fusion and a group of GTPases including Sar1, Arf, Arl and dynamin involved in vesicle budding/fission....
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | , , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
San Diego, California :
Elsevier/Academic Press,
�2006.
|
| Colección: | Methods in enzymology ;
v. 407. |
| Temas: | |
| Acceso en línea: | Texto completo Texto completo Texto completo |
Tabla de Contenidos:
- Ras and rap1 activation of plc[var epsilon] lipase activity / H. Edamatsu [and others]
- Specificity and expression of ralgps as ralgefs / L.A. Quilliam [and others]
- Biochemical and biological analyses of rgr ralgef oncogene / L.A. Martello [and others]
- Analysis of ras activation in living cells with gfp-rbd / T.G. Bivona [and others]
- Genetic and pharmacologic analyses of the role of icmt in ras membrane association and function / A.W. Svensson [and others]
- Characterization of the activation of the rap-specific exchange factor epac by cyclic nucleotides / H. Rehmann [and others]
- Biochemistry of the rap-specific guanine nucleotide exchange factors pdz-gef1 and -2 / H.B. Kuiperij [and others]
- Characterization of interactions between ras family gtpases and their effectors / P. RodriguezViciana [and others]
- Genetic and pharmacologic dissection of ras effector utilization in oncogenesis / P.M. Campbell [and others]
- Sequencing analysis of braf mutations in human cancers / R. Wooster [and others]
- Ksr regulation of the raf-mek-erk cascade / D.A. Ritt [and others]
- Ras-sensitive imp modulation of the raf/mek/erk cascade through ksr1 / S.A. Matheny [and others]
- Raf kinase inhibitor protein regulation of raf and mapk signaling / S. Hagan [and others]
- Harnessing rnai for analyses of ras signaling and transformation / A.W. Whitehurst [and others]
- The rac activator tiam1 and ras-induced oncogenesis / K. Strumane [and others]
- Phospholipase c[epsilon] guanine nucleotide exchange factor activity and activation of rap1 / T. Satoh [and others]
- Nore1 and rassf1 regulation of cell proliferation and of the mst1/2 kinases / J. Avruch [and others]
- Rassf family proteins and ras transformation / M.D. Vos [and others]
- Ras and the rain/rasip1 effector / N. Mitin [and others]
- The rin family of ras effectors / J.M. Bliss [and others]
- Rap1 regulation of riam and cell adhesion / E. Lafuente [and others]
- Regulation of cell-cell adhesion by rap1 / Y. Fujita [and others]
- Effects of ras signaling on gene expression analyzed by customized microarrays / O.I. Tchernitsa [and others]
- Protein-fragment complementation assays (pca) in small gtpase research and drug discovery / J.K. Westwick [and others]
- Ras up-regulation of cyclooxygenase-2 / M.G. Backlund [and others]
- Regulation of the expression of tropomyosins and actin cytoskeleton by ras transformation / G.L. Prasad [and others]
- Regulation of par-4 by oncogenic ras / K. Murthi Vasudevan [and others]
- Using drosophila and yeast genetics to investigate a role for the rheb gtpase in cell growth / P.H. Patel [and others].
- (Contents continued) Biochemistry and biology of arhi (diras3), an imprinted tumor suppressor gene whose expression is lost in ovarian and breast cancers / Y. Yu [and others]
- Gem protein signaling and regulation / Y. Ward [and others]
- Analyses of rem/rgk signaling and biological activity / D.A. Andres [and others]
- Analysis of rit signaling and biological activity / D.A. Andres [and others]
- Characterization of rerg: An estrogen-regulated tumor suppressor gene / M.D. Key [and others]
- Inhibition of transcription factor nf-[kappa]b activation by [kappa]b-ras / T. Huxford [and others]
- Analysis of rhes activation state and effector function / J. Bernal [and others]
- Rheb activation of mtor and s6k1 signaling / J. Hanrahan [and others]
- Use of retrovirus expression of interfering rna to determine the contribution of activated k-ras and ras effector expression to human tumor cell growth / A.T. Baines [and others]
- Using inhibitors of prenylation to block localization and transforming activity / A.C. Berzat [and others]
- Sorafenib (bay 43-9006, nexavar(r)), a dual-action inhibitor that targets raf/mek/erk pathway in tumor cells and tyrosine kinases vegfr/pdgfr in tumor vasculature / L. Adnane [and others]
- Yeast screens for inhibitors of ras-raf interaction and characterization of mcp inhibitors of ras-raf interaction / V. Khazak [and others]
- A tagging-via-substrate technology for genome-wide detection and identification of farnesylated proteins / S.C. Kim [and others]
- A genetically defined normal human somatic cell system to study ras oncogenesis in vivo and in vitro / K.M. O'Hayer [and others]
- Analysis of ras transformation of human thyroid epithelial cells / Z. Poghosyan [and others]
- Use of ras-transformed human ovarian surface epithelial cells as a model for studying ovarian cancer / D.G. Rosen [and others]
- Physiological analysis of oncogenic k-ras / P.A. PerezMancera [and others]
- Use of conditionally active ras fusion proteins to study epidermal growth, differentiation, and neoplasia / J.A. Reuter [and others]
- Pancreatic duct epithelial cell isolation and cultivation in two-dimensional and three-dimensional culture systems / C. Agbunag [and others]
- Analyses of ras regulation of eye development in drosophila melanogaster / L.C. Firth [and others].