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Epilepsy, infantile spasms, and developmental encephalopathy /
Epilepsy, Infantile Spasms, and Developmental Encephalopathy explores the nature and bases of infantile spasms - a major representative of the catastrophic developmental seizure disorders seen in early childhood. Although this topic has received considerable attention as a clinical disorder, the und...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Amsterdam ; Boston :
Academic,
2002.
|
| Colección: | International review of neurobiology ;
v. 49. |
| Temas: | |
| Acceso en línea: | Texto completo Texto completo |
MARC
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| 050 | 4 | |a RC341 |b .I5 vol. 49 |a RJ496.S58 | |
| 082 | 0 | 4 | |a 618.92845 |
| 245 | 0 | 0 | |a Epilepsy, infantile spasms, and developmental encephalopathy / |c edited by Philip A. Schwartzkroin and John M. Rho. |
| 260 | |a Amsterdam ; |a Boston : |b Academic, |c 2002. | ||
| 300 | |a 1 online resource. | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 490 | 1 | |a International review of neurobiology ; |v v. 49 | |
| 550 | |a Made available through: Science Direct. | ||
| 504 | |a Includes bibliographical references and references. | ||
| 520 | |a Epilepsy, Infantile Spasms, and Developmental Encephalopathy explores the nature and bases of infantile spasms - a major representative of the catastrophic developmental seizure disorders seen in early childhood. Although this topic has received considerable attention as a clinical disorder, the underlying pathogenesis of infantile spasms remains poorly understood. The aim is not simply to describe and label the clinical phenomenology associated with infantile spasms, but rather to work toward an understanding of the underlying mechanisms and of effective treatment strategies. The result is a volume with a high density of exciting ideas that can be taken to the bedside or to the laboratory for further study. Approaching the subject from an interdisciplinary perspective, this book integrates clinical and basic science in its discussion of infantile spasms as representative of a common developmental brain disorder. It also provides experimentally testable hypotheses to direct further research, and presents reviews of the literature associated with suggested underlying mechanisms. Epilepsy, Infantile Spasms, and Developmental Encephalopathy explores the nature and bases of infantile spasms - a major representative of the catastrophic developmental seizure disorders seen in early childhood. Although this topic has received considerable attention as a clinical disorder, the underlying pathogenesis of infantile spasms remains poorly understood. The aim is not simply to describe and label the clinical phenomenology associated with infantile spasms, but rather to work toward an understanding of the underlying mechanisms and of effective treatment strategies. The result is a volume with a high density of exciting ideas that can be taken to the bedside or to the laboratory for further study. | ||
| 588 | 0 | |a Online resource; title from HTML table of contents page (ScienceDirect, viewed Oct. 8, 2013). | |
| 505 | 0 | |a What is West Syndrome? -- Relationship between Encephalopathy and Abnormal Neuronal Activity in the Developing Brain -- Hypotheses from Functional Neuroimaging Studies -- Infantile Spasms: Unique Syndrome or General Age-Dependent Manifestation of a Diffuse Encephalopathy? -- Histopathology of Brain Tissue from Patients with Infantile Spasms -- Generators of Ictal and Interictal Electroencephalograms Associated with Infantile Spasms: Intracellular Studies of Cortical and Thalamic Neurons -- Cortical and Subcortical Generators of Normal and Abnormal Rhythmicity -- Role of Subcortical Structures in the Pathogenesis of Infantile Spasms: What are Possible Subcortical Mediators? -- What Must We Know to Develop Better Therapies? -- Treatment of Infantile Spasms: An Evidence-Based Approach -- ACTH Treatment of Infantile Spasms: Mechanisms of Its Effects in Modulation of Neuronal Excitability -- Neurosteroids and Infantile Spasms: The Deoxycorticosterone Hypothesis -- Are There Specific Anatomical and/or Transmitter Systems (Cortical or Subcortical) That Should Be Targeted? -- Medical versus Surgical Treatment: Which Treatment When -- Developmental Outcome with and without Successful Intervention -- Infantile Spasms versus Myoclonus: Is There a Connection? -- Tuberous Sclerosis as an Underlying Basis for Infantile Spasm -- Brain Malformations, Epilepsy, and Infantile Spasms -- Brain Maturational Aspects Relevant to Pathophysiology of Infantile Spasms -- Gene Expression Analysis as a Strategy to Understand the Molecular Pathogenesis of Infantile Spasms -- Infantile Spasms: Criteria for an Animal Model. | |
| 546 | |a English. | ||
| 650 | 0 | |a Infantile spasms. | |
| 650 | 0 | |a Epilepsy in children. | |
| 650 | 0 | |a Brain |x Diseases. | |
| 650 | 2 | |a Spasms, Infantile |0 (DNLM)D013036 | |
| 650 | 2 | |a Brain Diseases |0 (DNLM)D001927 | |
| 650 | 6 | |a Syndrome des spasmes en flexion. |0 (CaQQLa)201-0071460 | |
| 650 | 6 | |a �Epilepsie chez l'enfant. |0 (CaQQLa)201-0041314 | |
| 650 | 6 | |a Cerveau |x Maladies. |0 (CaQQLa)201-0001145 | |
| 650 | 7 | |a Brain |x Diseases. |2 fast |0 (OCoLC)fst00837607 | |
| 650 | 7 | |a Epilepsy in children. |2 fast |0 (OCoLC)fst00914207 | |
| 650 | 7 | |a Infantile spasms. |2 fast |0 (OCoLC)fst01128763 | |
| 650 | 7 | |a Medicine. |2 hilcc | |
| 650 | 7 | |a Health & Biological Sciences. |2 hilcc | |
| 650 | 7 | |a Pediatrics. |2 hilcc | |
| 650 | 7 | |a Neurology. |2 hilcc | |
| 700 | 1 | |a Schwartzkroin, P. A. |q (Philip A.), |e editor. | |
| 700 | 1 | |a Rho, Jong M., |e editor. | |
| 776 | 0 | 8 | |i Print version: |t Epilepsy, infantile spasms, and developmental encephalopathy (print) |w (DLC) 2002511042 |w (OCoLC)50323192 |
| 830 | 0 | |a International review of neurobiology ; |v v. 49. | |
| 856 | 4 | 0 | |u https://sciencedirect.uam.elogim.com/science/book/9780123668493 |z Texto completo |
| 856 | 4 | 0 | |u https://sciencedirect.uam.elogim.com/science/bookseries/00747742/49 |z Texto completo |
| 856 | 4 | 0 | |u https://sciencedirect.uam.elogim.com/science/bookseries/00747742/49 |z Texto completo |