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Measuring immunity : basic biology and clinical assessment /

Most of the diseases of modern mankind involve either acute or chronic inflammation. Measuring Immunity integrates the current information available on biomarkers and surrogate assays into a single handbook. It highlights the principles behind various applications, gives a brief summary on how they...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Lotze, Michael T., Thomson, Angus W.
Formato: Electrónico eBook
Idioma:Inglés
Publicado: San Diego, Calif. ; London : Elsevier Academic Press, �2005.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • MHC class I
  • MHC class II
  • Cytokine receptor heterogeneity
  • Genetic diversity at human cytokine loci in health and disease
  • Signaling molecules affecting immune response
  • Toll-like receptors in innate immunity
  • DNA sequence-specific transcription factors
  • Genetic diversity in NK and NKT cells
  • Handling sera and obtaining fluid from different compartments
  • Acute-phase proteins and inflammation
  • Complement in health and disease
  • Immunoglobulin titers and immunoglobulin subtypes
  • Human antiglobulin responses
  • Rheumatoid factors
  • Autoantibodies
  • Antibody affinity using fluorescence
  • SLE-associated tests
  • Multiplexed serum assays
  • Handling and storage of cells and sera: practical considerations
  • Phenotypic and functional measurements on circulating immune cells and their subsets
  • Natural killer cells
  • Tetramer analysis
  • Peripheral blood naive and memory B cells
  • Dendritic cells
  • Monocytes and macrophages
  • Tumor cells
  • Regulatory T cells
  • Intracellular cytokine assays
  • Cytolytic assays
  • Mixed leukocyte reactions
  • Antigen/mitogen-stimulated lymphocyte proliferation
  • Monitoring cell death
  • Cytokine enzyme linked immunosorbent spot (ELISPOT) assay
  • Testing natural killer cells
  • Delayed type hypersensitivity responses
  • Rebuck windows: granulocyte function
  • The vascular and coagulation systems
  • Sentinel node assays
  • Imaging inflammation
  • Cancer
  • solid tumors
  • Cancer
  • hematologic disorders
  • Autoimmunity
  • rheumatoid arthritis
  • Autoimmunity
  • type 1 diabetes
  • Autoimmunity
  • systemic lupus erythematosus
  • Autoimmunity
  • multiple sclerosis
  • Autoimmunity
  • inflammatory bowel disease
  • Autoimmunity
  • endocrine
  • Autoimmunity
  • vasculitis
  • Transplantation
  • Viral responses
  • HIV-1
  • Viral responses
  • epstein-barr virus
  • Viral responses
  • hepatitis
  • Dermatology
  • Arteriosclerosis
  • Primary immunodeficiencies
  • Asthma and allergy
  • Serum proteomic profiling and analysis
  • Imaging cytometry
  • Cancer biometrics
  • Genomics and microarrays
  • Image informatics.