GTPases regulating membrane dynamics /

GTPases that regulate the myriad of membrane fission events that facilitate the assembly and disassembly of COPII (Sar1), COPI (ARF) and clathrin coats (dynamin) involved in exocytic and endocytic trafficking pathways and mitochrondrial organization remain a major challenge for future investigations...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Balch, William Edward, 1949- (Editor ), Der, Channing J. (Editor ), Hall, A. (Alan) (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: San Diego, California : Elsevier Academic Press, �2005.
Colección:Methods in enzymology ; v. 404.
Temas:
Enzymes.
Membrane fusion.
Membranes (Biology)
GTP Phosphohydrolases > physiology
Cell Membrane > physiology
Enzymes
Membrane Fusion
Membranes
Fusion membranaire.
Membranes (Biologie)
enzyme.
Biologie
Biomembran
Dynamik
Regulation
Guanosintriphosphatasen
Human Anatomy & Physiology.
Health & Biological Sciences.
Animal Biochemistry.
fosfoglyceraat kinase (gtp)
phosphoglycerate kinase (gtp)
celmembranen
cell membranes
Proteins and Enzymes
Eiwitten en enzymen
Acceso en línea:Texto completo
Texto completo
Texto completo
Descripción
Sumario:GTPases that regulate the myriad of membrane fission events that facilitate the assembly and disassembly of COPII (Sar1), COPI (ARF) and clathrin coats (dynamin) involved in exocytic and endocytic trafficking pathways and mitochrondrial organization remain a major challenge for future investigations to understand membrane architecture of eukaryotic cells. This volume of MIE provides a comprehensive set of articles describing the use and application of state-of-the-art methodologies to identify and characterize these GTPases and their rapidly expanding list of regulators and effectors. Methodologies focused on biochemical, molecular and advanced imaging techniques provide a wealth of investigational tools for those currently in the field and those entering the field. Many of the methodologies are generally applicable to study of these GTPases in vitro and in vivo to elucidate function in regulation of cell proliferation and signaling in normal tissue and in disease. *Comprehensive collection of GTPases (ARF, Sar1, Dynamin) GTPases involved in vesicle coat assembly and membrane fission *Identification and characterization of GTPase GEFs, GAPs and effectors *General methodologies to study GTPase function in vitro and in vivo.
Descripción Física:1 online resource (xliii, 692 pages, 6 unnumbered pages of plates) : illustrations (some color).
Bibliografía:Includes bibliographical references and index.
ISBN:0121828093
9780121828097
ISSN:0076-6879 ;

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