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Quantitative pharmacology and individualized therapy strategies in development of therapeutic proteins for immune-mediated inflammatory diseases /
"Focused on quantitative pharmacology and individualized therapy for developing biotherapeutics in immune-mediated inflammatory diseases, this book discusses both theoretical and practical aspects and includes case studies illustrating applications in drug development. Provides frontline knowle...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Hoboken, NJ :
Wiley,
2019.
|
| Temas: | |
| Acceso en línea: | Texto completo (Requiere registro previo con correo institucional) |
MARC
| LEADER | 00000cam a2200000 i 4500 | ||
|---|---|---|---|
| 001 | OR_on1061865433 | ||
| 003 | OCoLC | ||
| 005 | 20231017213018.0 | ||
| 006 | m o d | ||
| 007 | cr ||||||||||| | ||
| 008 | 181105s2019 nju ob 001 0 eng | ||
| 010 | |a 2018053075 | ||
| 040 | |a DLC |b eng |e rda |c DLC |d DG1 |d YDX |d N$T |d EBLCP |d OCLCF |d UAB |d CHVBK |d MERER |d DLC |d OCLCO |d OCLCA |d OCLCO |d K6U |d OCL |d OCLCQ |d OCLCO | ||
| 019 | |a 1086209622 | ||
| 020 | |a 9781119289210 |q (Adobe PDF) | ||
| 020 | |a 1119289211 | ||
| 020 | |a 9781119289227 |q (ePub) | ||
| 020 | |a 111928922X | ||
| 020 | |z 9781119289197 |q (hardback) | ||
| 020 | |a 9781119289234 |q (electronic bk. ; |q oBook) | ||
| 020 | |a 1119289238 |q (electronic bk. ; |q oBook) | ||
| 029 | 1 | |a CHVBK |b 559026838 | |
| 029 | 1 | |a CHNEW |b 001039220 | |
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| 035 | |a (OCoLC)1061865433 |z (OCoLC)1086209622 | ||
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| 050 | 1 | 0 | |a RC600 |
| 060 | 1 | 0 | |a WD 305 |
| 072 | 7 | |a HEA |x 039000 |2 bisacsh | |
| 072 | 7 | |a MED |x 014000 |2 bisacsh | |
| 072 | 7 | |a MED |x 022000 |2 bisacsh | |
| 072 | 7 | |a MED |x 112000 |2 bisacsh | |
| 072 | 7 | |a MED |x 045000 |2 bisacsh | |
| 082 | 0 | 0 | |a 616.97/806 |2 23 |
| 049 | |a UAMI | ||
| 245 | 0 | 0 | |a Quantitative pharmacology and individualized therapy strategies in development of therapeutic proteins for immune-mediated inflammatory diseases / |c edited by Honghui Zhou, Diane R. Mould. |
| 264 | 1 | |a Hoboken, NJ : |b Wiley, |c 2019. | |
| 300 | |a 1 online resource | ||
| 336 | |a text |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 500 | |a "John Wiley & Sons Inc."--tp verso. | ||
| 504 | |a Includes bibliographical references and index. | ||
| 520 | |a "Focused on quantitative pharmacology and individualized therapy for developing biotherapeutics in immune-mediated inflammatory diseases, this book discusses both theoretical and practical aspects and includes case studies illustrating applications in drug development. Provides frontline knowledge of using PK/PD modeling tools to address a variety of problems in development of therapeutic proteins. Reviews and discusses biomarkers, systems pharmacology, PBPK modeling, and target-mediated modeling, as translational tools. Helps readers understand disease progression and identify of mechanisms-based biomarkers with clinical relevance"--Provided by publisher. | ||
| 588 | |a Description based on print version record and CIP data provided by publisher. | ||
| 505 | 0 | |a Disease Interception in Autoimmune Diseases: From a Conceptual Framework to Practical Implementation / Anish Suri -- The Role of Biomarkers in Treatment Algorithms for Ulcerative Colitis (UC) / Reena Khanna, Brian G Feagan -- Mechanism and Physiologically Based PK/PD Model in Assisting Translation from Preclinical to Clinical: Understanding PK/PD of Therapeutic Proteins at Site-of-Action / Xi Chen, Weirong Wang -- Application of Minimal Anticipated Biological Effect Level (MABEL) in Human Starting Dose Selection for Immunomodulatory Protein Therapeutics -- Principles and Case Studies / Haiqing Wang, Zheng Yang, Rong Shi -- Model-Based Meta-Analysis Use in the Development of Therapeutic Proteins / Timothy J Taylor, Bill Frame, Angela D Taylor -- Utility of Joint Population Exposure-Response Modeling Approach to Assess Multiple Continuous and Categorical Endpoints in Immunology Drug Development / Chuanpu Hu, Honghui Zhou -- Modeling Approaches to Characterize Target-Mediated Pharmacokinetics and Pharmacodynamics for Therapeutic Proteins / Leonid Gibiansky, Ekaterina Gibiansky -- Tutorial: Numerical (NONMEM) Implementation of the Target-Mediated Drug Disposition Model / Leonid Gibiansky, Ekaterina Gibiansky -- Translational Considerations in Developing Bispecific Antibodies: What Can We Learn from Quantitative Pharmacology? / Pradeep B Lukka, Santosh Wagh, Bernd Meibohm -- Application of Pharmacometrics and Systems Pharmacology to Current and Emerging Biologics in Inflammatory Bowel Diseases / Sihem Ait-Oudhia, Yi Ting (Kayla) Lien, Sumit Basu, Lawrence Lesko, Stephan Schmidt -- Pharmacokinetics-Based Dosing for Therapeutic Monoclonal Antibodies in Inflammatory Bowel Disease / Niels Vande Casteele, William J Sandborn -- Pharmacokinetics-Based Dosing Strategies for Therapeutic Proteins in Inflammatory Bowel Disease / Diane R Mould, Richard N Upton, Jessica Wojciechowski -- Quantitative Pharmacology Approach to Select Optimal Dose and Study the Important Factors in Determining Disposition of Therapeutic Monoclonal Antibody in Pediatric Subjects -- Some Considerations / Deni Hardiansyah, Chee M Ng -- Quantitative Pharmacology Assessment Strategy Therapeutic Proteins in Pediatric Subjects -- Challenges and Opportunities / Jeremiah D Momper, Andrew Mulberg, Nitin Mehrotra, Dan Turner, William Faubion, Laurie Conklin, Karim Azer, Marla C Dubinsky -- Case Examples of Using Quantitative Pharmacology in Developing Therapeutic Proteins for Plaque Psoriasis -- Guselkumab / Zhenling Yao, Yaowei Zhu, Chuanpu Hu, Yang Chen, Shu Li, Bruce Randazzo, Zhenhua Xu, Amarnath Sharma, Honghui Zhou -- Vedolizumab-A Case Example of Using Quantitative Pharmacology in Developing Therapeutic Biologics in Inflammatory Bowel Disease / Maria Rosario, Nathanael L Dirks, Diane R Mould, Catherine Scholz, Timothy Wyant, Asit Parikh, Irving Fox -- Case Examples of Using Quantitative Pharmacology in Developing Therapeutic Proteins in Systemic Lupus Erythematosus -- Belimumab / Herbert Struemper -- Case Examples of Using Quantitative Pharmacology in Developing Therapeutic Proteins in Multiple Sclerosis -- Peginterferon Beta-1a, Daclizumab Beta, Natalizumab / Xiao Hu, Yaming Hang, Lei Diao, Kumar K Muralidharan, Ivan Nestorov -- Index -- Supplemental Images. | |
| 590 | |a O'Reilly |b O'Reilly Online Learning: Academic/Public Library Edition | ||
| 650 | 0 | |a Immunologic diseases |x Treatment. | |
| 650 | 0 | |a Pharmacology. | |
| 650 | 0 | |a Mathematical models. | |
| 650 | 1 | 2 | |a Autoimmune Diseases |x drug therapy |
| 650 | 1 | 2 | |a Proteins |x therapeutic use |
| 650 | 2 | 2 | |a Proteins |x pharmacokinetics |
| 650 | 2 | 2 | |a Protein Engineering |x methods |
| 650 | 2 | 2 | |a Models, Theoretical |
| 650 | 2 | |a Pharmacology | |
| 650 | 6 | |a Maladies immunologiques |x Traitement. | |
| 650 | 6 | |a Pharmacologie. | |
| 650 | 6 | |a Modèles mathématiques. | |
| 650 | 7 | |a pharmacology. |2 aat | |
| 650 | 7 | |a mathematical models. |2 aat | |
| 650 | 7 | |a HEALTH & FITNESS |x Diseases |x General. |2 bisacsh | |
| 650 | 7 | |a MEDICAL |x Clinical Medicine. |2 bisacsh | |
| 650 | 7 | |a MEDICAL |x Diseases. |2 bisacsh | |
| 650 | 7 | |a MEDICAL |x Evidence-Based Medicine. |2 bisacsh | |
| 650 | 7 | |a MEDICAL |x Internal Medicine. |2 bisacsh | |
| 650 | 7 | |a Mathematical models |2 fast | |
| 650 | 7 | |a Immunologic diseases |x Treatment |2 fast | |
| 650 | 7 | |a Pharmacology |2 fast | |
| 700 | 1 | |a Zhou, Honghui, |e editor. | |
| 700 | 1 | |a Mould, Diane R. |q (Diane Renee), |d 1960- |e editor. | |
| 776 | 0 | 8 | |i Print version: |t Quantitative pharmacology and individualized therapy strategies in development of therapeutic proteins for immune-mediated inflammatory diseases |b First edition. |d Hoboken, NJ : Wiley, [2019] |z 9781119289197 |w (DLC) 2018051418 |
| 856 | 4 | 0 | |u https://learning.oreilly.com/library/view/~/9781119289197/?ar |z Texto completo (Requiere registro previo con correo institucional) |
| 938 | |a YBP Library Services |b YANK |n 16080648 | ||
| 938 | |a YBP Library Services |b YANK |n 16055307 | ||
| 938 | |a EBSCOhost |b EBSC |n 2030089 | ||
| 938 | |a ProQuest Ebook Central |b EBLB |n EBL5709855 | ||
| 994 | |a 92 |b IZTAP | ||