Cargando…

Open-space microfluidics : concepts, implementations, applications /

Summarizing the latest trends and the current state of this research field, this up-to-date book discusses in detail techniques to perform localized alterations on surfaces with great flexibility, including microfluidic probes, multifunctional nanopipettes and various surface patterning techniques,...

Descripción completa

Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Delamarche, Emmanuel (Editor ), Kaigala, Govind V. (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Weinheim, Germany : Wiley-VCH, [2018]
Temas:
Acceso en línea:Texto completo (Requiere registro previo con correo institucional)
Tabla de Contenidos:
  • Intro; Title Page; Copyright; Table of Contents; Foreword; Preface; Part I: Hydrodynamic Flow Confinement (HFC); Chapter 1: Hydrodynamic Flow Confinement Using a Microfluidic Probe; 1.1 Introduction; 1.2 HFC Principle; 1.3 MFP Heads; 1.4 Vertical MFP; 1.5 Advanced MFP Heads and Holders; 1.6 Surface Processing Using an MFP; 1.7 MFP Components; 1.8 Outlook; Acknowledgments; References; Chapter 2: Hierarchical Hydrodynamic Flow Confinement (hHFC) and Recirculation for Performing Microscale Chemistry on Surfaces; 2.1 Introduction; 2.2 Hierarchical HFC; 2.3 Recirculation; 2.4 Microscale Deposition.
  • AcknowledgmentsReferences; Chapter 3: Design of Hydrodynamically Confined Microflow Devices with Numerical Modeling: Controlling Flow Envelope, Pressure, and Shear Stress; 3.1 Introduction; 3.2 Theory; 3.3 Device and Experimental Methods for CFD Validation; 3.4 Numerical Modeling of HCM devices; 3.5 Envelope Size and Pressure Drop Across HCMs; 3.6 Hydrodynamic Loads Generated by HCM Devices; 3.7 Concluding Remarks; References; Chapter 4: Hele-Shaw Flow Theory in the Context of Open Microfluidics: From Dipoles to Quadrupoles; 4.1 Introduction; 4.2 Fundamentals of Hele-Shaw Flows.
  • 4.3 Applications to Microfluidic Dipoles and Quadrupoles4.4 Diffusion in Hele-Shaw Flows; 4.5 Conclusion; References; Chapter 5: Implementation and Applications of Microfluidic Quadrupoles; 5.1 Introduction; 5.2 Principles and Configurations of MQs; 5.3 Implementation of MQs; 5.4 MQ Analysis and Characterization; 5.5 Application of MQs in Biology and Life Sciences; 5.6 Summary and Outlook; References; Chapter 6: Hydrodynamic Flow Confinement-Assisted Immunohistochemistry from Micrometer to Millimeter Scale; 6.1 Immunohistochemical Analysis of Tissue Sections.
  • 6.2 Probe Heads for Multiscale Surface Interactions6.3 Immunohistochemistry with Microfluidic Probes; 6.4 Micro-IHC on Human Tissue Sections; 6.5 Millimeter-Scale Immunohistochemistry; 6.6 Outlook; Acknowledgments; References; Chapter 7: Local Nucleic Acid Analysis of Adherent Cells; 7.1 Introduction; 7.2 Methods; 7.3 Results; 7.4 Discussion; 7.5 Concluding Remarks; Acknowledgments; References; Chapter 8: Microfluidic Probe for Neural Organotypic Brain Tissue and Cell Perfusion; 8.1 Introduction; 8.2 Microperfusion of Organotypic Brain Slices Using the Microfluidic Probe.
  • 8.3 Microperfusion of Live Dissociated Neural Cell Cultures Using the Microfluidic Probe8.4 Conclusion; Acknowledgments; References; Chapter 9: The Multifunctional Pipette; 9.1 Introduction; 9.2 Open Volume Probes; 9.3 Detailed View on the Multifunctional Pipette; 9.4 Integrated Functions; 9.5 Functional Extensions and Applications; 9.6 Future Technology; Acknowledgments; References; Chapter 10: Single-Cell Analysis with the BioPen; 10.1 Introduction; 10.2 The Single-Cell Challenge; 10.3 Superfusion Techniques; 10.4 The BioPen; 10.5 Application Areas; 10.6 Future Technology; Acknowledgments.