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Micro- and nanoengineering of the cell surface /

Micro- and Nanoengineering of the Cell Surface explores the direct engineering of cell surfaces, enabling materials scientists and chemists to manipulate or augment cell functions and phenotypes. The book is accessible for readers across industry, academia, and in clinical settings in multiple disci...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Karp, Jeffrey M., Zhao, Weian
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Oxford, UK ; San Diego, CA : William Andrew, ©2014.
Colección:Micro & nano technologies.
Temas:
Acceso en línea:Texto completo (Requiere registro previo con correo institucional)

MARC

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245 0 0 |a Micro- and nanoengineering of the cell surface /  |c edited by Jeffrey M. Karp, Weian Zhao. 
260 |a Oxford, UK ;  |a San Diego, CA :  |b William Andrew,  |c ©2014. 
300 |a 1 online resource :  |b illustrations 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
490 1 |a Micro & nano technologies series 
588 0 |a Online resource; title from title page (Safari, viewed July 2, 2014). 
504 |a Includes bibliographical references and index. 
505 0 |a Front Cover; Micro- and Nanoengineering of the Cell Surface; Copyright Page; Contents; Foreword; List of Contributors; 1 Cell Membrane Biology and Juxtacrine Signal Conversion; 1.1 Introduction; 1.2 Cell membrane biology-early milestones; 1.3 Membrane microdomains; 1.4 Cell membrane emergence; 1.5 Juxtacrine signaling and rewiring cellular networks; 1.6 Protein painting, artificial veto cell engineering; 1.7 Trans signal conversion; 1.8 Redirecting juxtacrine signals; 1.9 Creating auto-signaling loops; 1.10 SCP therapeutic flexibility; 1.11 The cell membrane frontier; References. 
505 8 |a 2 Cell Surface Engineering by Chemical Reaction and Remodeling2.1 Introduction; 2.2 Methods and technology of covalent cell surface reaction; 2.2.1 Direct chemical modification of cell membrane; 2.2.2 Indirect chemical modification of cell membrane; 2.3 Relevance of covalent cell surface modification; 2.4 Future perspectives; 2.5 Conclusions; References; 3 Bioconjugation Reactions in Living Cells: Development, Advances, and Applications of Glycan-Specific Technologies; 3.1 Introduction; 3.2 Bioorthogonal chemical ligation reactions for glycan labeling. 
505 8 |a 3.2.1 Aldehyde- and Ketone-Based Bioorthogonal Reactions3.2.1.1 Aldehyde-Based Reactions; 3.2.1.2 Metabolic Incorporation Expands Bioorthogonal Ligation to Include Ketone-Based Reactions; 3.2.2 Azide- and Alkyne-Based Bioorthogonal Reactions; 3.2.2.1 Classical and Modified Staudinger Ligation Reactions; 3.2.2.2 Click Reactions: the Copper-Catalyzed [3+2] Azide-Alkyne Cycloaddition; 3.2.2.3 Strain-Promoted Azide-Alkyne Cycloaddition Reactions; 3.2.3 Thiol-based Chemistry; 3.2.4 Photoactivated Ligation Reactions; 3.2.4.1 Benzophenones; 3.2.4.2 Arylazides; 3.2.4.3 Diazirines. 
505 8 |a 3.3 Bioorthogonal ligation reactions: exploitation in MOE-based applications3.3.1 MOE Extends Beyond N-Acyl-Modified Sialic Acid; 3.3.2 Imaging of Living Cells; 3.3.3 In vivo Labeling/Imaging; 3.3.4 Tissue Engineering, Stem Cell Research, and Regenerative Medicine; 3.3.5 Cancer Therapy; 3.4 Concluding comments; References; 4 Pushing the Bacterial Envelope: Strategies for Re-Engineering Bacterial Surfaces with Heterologous Proteins and Sugars; 4.1 Bacterial surface display; 4.2 Strategies for re-engineering bacterial surfaces with heterologous proteins; 4.2.1 Gram-Negative Organisms. 
505 8 |a 4.2.2 Gram-Positive Organisms4.2.3 Spores; 4.2.4 Outer Membrane Vesicles and Bacterial Ghosts; 4.3 Applications of bacteria expressing heterologous surface proteins; 4.3.1 Vaccines Against Infectious Disease; 4.3.2 Anticancer Therapeutics; 4.3.3 Vaccines Against Cancer; 4.3.4 Biocatalysis; 4.3.5 Interactions Between Surface Proteins and Solutes; 4.3.5.1 Biosensing: Binding for Purposes of Detection; 4.3.5.2 Biosorption: Binding for Purposes of Purification; 4.3.5.3 Screening: Binding for Purposes of Identification; 4.4 Strategies for re-engineering bacterial surfaces with heterologous sugars. 
520 |a Micro- and Nanoengineering of the Cell Surface explores the direct engineering of cell surfaces, enabling materials scientists and chemists to manipulate or augment cell functions and phenotypes. The book is accessible for readers across industry, academia, and in clinical settings in multiple disciplines, including materials science, engineering, chemistry, biology, and medicine. Written by leaders in the field, it covers numerous cell surface engineering methods along with their current and potential applications in cell therapy, tissue engineering, biosensing, and diagnosis.> 
590 |a O'Reilly  |b O'Reilly Online Learning: Academic/Public Library Edition 
650 0 |a Biomedical engineering. 
650 0 |a Nanotechnology. 
650 0 |a Cells  |x Microbiology. 
650 0 |a Ultrastructure (Biology) 
650 0 |a Bacterial cell surfaces. 
650 6 |a Génie biomédical. 
650 6 |a Cellules  |x Microbiologie. 
650 6 |a Ultrastructure (Biologie) 
650 6 |a Surface bactérienne. 
650 7 |a biomedical engineering.  |2 aat 
650 7 |a ultrastructure.  |2 aat 
650 7 |a Bacterial cell surfaces.  |2 fast  |0 (OCoLC)fst00825189 
650 7 |a Biomedical engineering.  |2 fast  |0 (OCoLC)fst00832568 
650 7 |a Nanotechnology.  |2 fast  |0 (OCoLC)fst01032639 
650 7 |a Ultrastructure (Biology)  |2 fast  |0 (OCoLC)fst01160738 
700 1 |a Karp, Jeffrey M. 
700 1 |a Zhao, Weian. 
776 0 8 |i Print version:  |z 9781306859714 
830 0 |a Micro & nano technologies. 
856 4 0 |u https://learning.oreilly.com/library/view/~/9781455731466/?ar  |z Texto completo (Requiere registro previo con correo institucional) 
938 |a Askews and Holts Library Services  |b ASKH  |n AH25543898 
938 |a ProQuest MyiLibrary Digital eBook Collection  |b IDEB  |n cis28460754 
994 |a 92  |b IZTAP