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Bioinformatics and biomarker discovery : "omic" data analysis for personalised medicine /

This book is designed to introduce biologists, clinicians and computational researchers to fundamental data analysis principles, techniques and tools for supporting the discovery of biomarkers and the implementation of diagnostic/prognostic systems. The focus of the book is on how fundamental statis...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Azuaje, Francisco
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Chichester, West Sussex, U.K. ; Hoboken, NJ : John Wiley & Sons, 2010.
Temas:
Acceso en línea:Texto completo (Requiere registro previo con correo institucional)
Tabla de Contenidos:
  • Biomarkers and bioinformatics
  • Review of fundamental statistical concepts
  • Biomarker-based prediction models: design and interpretation principles
  • An introduction to the discovery and analysis of genotype-phenotype associations
  • Integrative approaches to genotype-phenotype association discovery
  • Biomarkers and gene expression data analysis
  • Advances in biomarker discovery with gene expression data
  • Proteomics and metabolomics for biomarker discovery: an introduction to spectral data analysis
  • Data integration in proteomics and metabolomics for biomarker discovery
  • Disease biomarkers and biological interaction networks
  • Commentary on disease biomarkers and biological interaction networks
  • Integrative data analysis for biomarker discovery
  • Data integration: the next big hope?
  • Information resources and software tools for biomarker discovery
  • Challenges and research directions in bioinformatics and biomarker discovery
  • Towards building knowledge-based assistants for intelligent data analysis in biomarker discovery
  • Accompanying commentary on challenges and opportunities of bioinformatics in disease biomarker discovery.