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Structural bioinformatics /
The second edition of this successful text expands on the depth and scope of the topic by bringing together many of the world's experts to provide a view of the current state of the field suitable for advanced undergraduate students, graduate students and beyond. The book begins with a descript...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Hoboken, N.J. :
Wiley-Blackwell,
©2009.
|
| Edición: | 2nd ed. |
| Colección: | Methods of biochemical analysis ;
v. 44. |
| Temas: | |
| Acceso en línea: | Texto completo (Requiere registro previo con correo institucional) |
Tabla de Contenidos:
- Data Collection, Analysis, and Visualization
- Defining Bioinformatics and Structural Bioinformatics / Russ B. Altman, Jonathan M. Dugan
- Fundamentals of Protein Structure / Eric D. Scheef, J. Lynn Fink
- Fundamentals of DNA and RNA Structure / Stephen Neidle, Bohdan Schneider, Helen M. Berman
- Computational Aspects of High-Throughput Crystallographic Macromolecular Structure Determination / Paul D. Adams, Ralf W. Grosse-Kunstleve, Axel T. Brunger
- Macromolecular Structure Determination by NMR Spectroscopy / John L. Markley, Arash Bahrami, Hamid R. Eghbalnia, Francis C. Peterson, Robert C. Tyler, Eldon L. Ulrich, William M. Westler, Brian F. Volkman
- Electron Microscopy in the Context of Structural Systems Biology / Niels Volkmann, Dorit Hanein
- Study of Protein Three-Dimensional Structure and Dynamics Using Peptide Amide Hydrogen/Deuterium Exchange Mass Spectrometry (DXMS) and Chemical Cross-Linking With Mass Spectrometry to Constrain Molecular Modeling / Sheng Li, Dmitri Mouradov, Gordon King, Tong Liu, Ian Ross, Bostjan Kobe, Virgil L. Woods, Jr., Thomas Huber
- Search and Sampling in Structural Bioinformatics / Han Samish
- Molecular Visualization / Steven Bottomley, Erik Helmerhorst.
- Data representation and databases
- The PDB Format, mmCIF Formats, and Other Data Formats / John D. Westbrook, Paula M.D. Fitzgerald
- The Worldwide Protein Data Bank / Helen M. Berman, Kim Henrick, Haruki Nakamura, John L. Markley
- The Nucleic Acid Database / Bohdan Schneider, Joanna de la Cruz, Zukang Feng, Li Chen, Shuchismita Dutta, Irina Persikova, John D. Westbrook, Huanwang Yang, Jasmine Young, Christine Zardecki, Helen M. Berman
- Other Structure-Based Databases / J. Lynn Fink, Helge Weissig, and Philip E. Bourne.
- Data integrity and comparative features
- Structural Quality Assurance / Roman A. Laskowski
- The Impact of Local Accuracy in Protein and RNA Structures: Validation as an Active Tool / Jane S. Richardson, David C. Richardson
- Structure Comparison and Alignment / Marc A. Marti-Renom, Emidio Capriotti, Ilya N. Shindyalov, Philip E. Bourne
- Protein Structure Evolution and the SCOP Database / Raghu P.R. Metpally, Boojala V.B. Reddy
- The CATH Domain Structure Database / Frances M.G. Pearl, Alison Cuff, Christine A. Orengo.
- Structural and functional assignment
- Secondary Structure Assignment / Claus A. Andersen, Burkhard Rost
- Identifying Structural Domains in Proteins / Stella Veretnik, Jenny Gu, Shoshana Wodak
- Inferring Protein Function from Structure / James D. Watson, Gail J. Bartlett, Janet M. Thornton
- Structural Annotation of Genomes / Adam J. Reid, Corin Yeats, Jonathan Lees, Christine A. Orengo
- Evolution Studied Using Protein Structure / Song Yang, Ruben Valas, Philip E. Bourne.
- Macromolecular interactions
- Electrostatic Interactions / Nathan A. Baker, J. Andrew McCammon
- Prediction of Protein-Nucleic Acid Interactions / Timothy Robertson, Gabriele Varani
- Prediction of Protein-Protein Interactions from Evolutionary Information / Alfonso Valencia, Florencio Pazos
- Docking Methods, Ligand Design, and Validating Data Sets in the Structural Genomics Era / Natasja Brooijmans.
- Structure prediction
- CASP and Other Community-Wide Assessments to Advance the Field of Structure Prediction / Jenny Gu, Philip E. Bourne
- Prediction of Protein Structure in 1D: Secondary Structure, Membrane Regions, and Solvent Accessibility / Burkhard Rost
- Homology Modeling / Hanka Venselaar, Elmar Krieger, Gert Vriend
- Fold Recognition Methods / Adam Godzik
- De Novo Protein Structure Prediction: Methods and Application / Kevin Drew, Dylan Chivian, Richard Bonneau
- RNA Structural Bioinformatics / Magdalena A. Jonikas, Alain Laederach, Russ B. Altman.
- Therapeutic discovery
- Structural Bioinformatics in Drug Discovery / William R. Pitt, Alicia Perez Higueruelo, Colin R. Groom
- B-Cell Epitope Prediction / Julia V. Ponomarenko, Marc H.V. van Regenmortel.
- Future Challenges
- Methods to Classify and Predict the Structure of Membrane Proteins / Marialuisa Pellegrini-Calace, Janet M. Thornton
- Protein Motion: Simulation / Ilan Samish, Jenny Gu, Michael L. Klein
- The Significance and Impacts of Protein Disorder and Conformational Variants / Jenny Gu, Vincent J. Hilser
- Protein Designability and Engineering / Nikolay V. Dokholyan
- Structural Genomics of Protein Superfamilies / Stephen K. Burley, Steven C. Almo, Jeffrey B. Bonanno
- Mark R. Chance, Spencer Emtage, Andras Fiser, Andrej Sali, J. Michael Sauder, Subramanyam Swaminathan.