Bioreactors : analysis and design /

"In recent times, the field of Biology has seen many changes and advancements. This evolution makes a good knowledge about the bioreactor and its operation inevitable for all professionals and students working in this area. Bioreactors: Analysis and Design, arguably the first of its kind, will...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Panda, Tapobrata (Autor)
Formato: Electrónico eBook
Idioma:Inglés
Publicado: New York, N.Y. : McGraw-Hill Education, [2011]
Edición:First edition.
Colección:McGraw-Hill's AccessEngineering.
Temas:
Bioreactors.
Bioreactors > Design.
Electronic books.
Acceso en línea:Texto completo
Tabla de Contenidos:
  • A. Dedication
  • B. Preface
  • C. Acknowledgements
  • D. Author's profile
  • 1. Introduction
  • Overview of biological reactions
  • Elements in bioreactor design
  • Rate expression in biological systems
  • Basic concept of energy transfer
  • Basic concept of mass balance
  • Exercises
  • References
  • Appendix 1
  • References to appendix 1
  • 2. Understanding of bioreactors
  • What is a bioreactor?
  • Why should we study bioreactors?
  • Development of bioreactors
  • Purpose and importance of bioreactors
  • Other bioreactor configurations
  • Bioreactor development for solid-state fermentation (SSF)
  • Classification of bioreactors
  • Bioreactors for animal cell cultivation
  • Bioreactors for plant cell culture
  • Bioreactors for immobilized system
  • Sterilization bioreactors
  • Bioreactors used in different areas of environmental control and management
  • Bioreactors used for combined reactions and separation
  • Exercises
  • References
  • Further reading
  • 3. Bioreactor operation
  • Introduction
  • Common operations of bioreactor
  • Selection/identification of other common factors necessary for smooth operation of bioreactors
  • Spectrum of basic bioreactor operations
  • Reactor operation for immobilized systems
  • Operation of animal cell bioreactors
  • Operation of bioreactors for plant cell culture
  • Reactors for waste management
  • Exercises
  • References
  • Appendix 3
  • 4. Biochemical aspect of bioreactor design
  • Introduction
  • Organization of this chapter
  • Introduction to section a: part 1
  • Introduction to section a: part 2
  • Plug flow tubular reactor (PFTR)
  • Recycle bioreactors
  • Combination of bioreactors
  • Semi-continuous bioreactors
  • Introduction to section B
  • Input to kinetic modeling of enzyme reactors
  • Example problems
  • Exercises
  • References
  • 5. Analysis of non-ideal behavior in bioreactors
  • Introduction
  • Non-ideal parameters
  • Residence time distribution?some aspects of macro mixing
  • Some exercise for RTD of ideal systems (ideal bioreactors)
  • Moments of the distribution
  • E(t) or f(t) and the bioreactor design
  • Models for non-ideal flow
  • Multi parameter models
  • Application of RTD based models to non-ideal bioreactors
  • Drawbacks of classical RTD measurements
  • Transient behavior in bioreactors
  • Stability analysis for continuous flow bioreactor with substrate inhibition
  • Phase plane analysis
  • The bifurcation analysis
  • Exercises
  • References.
  • 6. Bioreactor modeling
  • Model?what is it?
  • Definition of lumped and distributed parameter models
  • Introduction to a few terminologies and theorems
  • Modeling principles
  • Steps in modeling
  • Fundamental laws used in process modeling
  • First?order systems
  • Second-order systems
  • Complexity of the model
  • Parameter sensitivity
  • Exercises
  • References
  • Appendix 6
  • 7. Transport processes in bioreactors
  • Introduction
  • Heat transfer
  • Other parameters influencing transfer operations
  • Exercises
  • References
  • 8. Controls in bioreactors
  • Introduction
  • Control tasks in a bioreactor system
  • Instrumentation to control a bioreactor
  • Controlled variables and measurement devices
  • Procedure for design of efficient control systems
  • Conventional control techniques
  • Advanced control techniques
  • Consistency checks on measurements
  • Adaptive online optimizing control of bioreactor system
  • Exercises
  • References
  • Appendix 8
  • 9. Case studies
  • Introduction
  • Design of packed bed bioreactor
  • Airlift bioreactors
  • Hollow fiber bioreactor (HFBR)
  • Plant cell bioreactor
  • Design of bioreactors for solid state fermentation (SSF)
  • Mammalian cell bioreactor design
  • Exercises
  • References
  • Appendix 9
  • 10. Application of computational fluid dynamics in bioreactor analysis and design
  • Introduction
  • Fluid dynamic modeling
  • Simulation
  • Exercises
  • References
  • Appendix 10
  • 11. Scale-up of bioreactors
  • Introduction
  • Additional scale-up problems in bioreactors
  • Criteria of scale-up
  • Similarity criteria
  • Scale-up methods
  • Generalized approaches to scale-up in combination of methods
  • Examples
  • Exercises
  • References
  • 12. Mechanical aspects of bioreactor design
  • Introduction
  • Requirements for construction of a bioreactor
  • Guidelines for bioreactor design
  • Bioreactor vessels
  • Agitator assembly
  • Exercises
  • References
  • Appendix 12.

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