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Production and Quality Control of Fluorine-18 Labelled Radiopharmaceuticals

Since their clinical use initiation in the 1970's, Fluorine-18 (F-18) radiopharmaceuticals continue to play an important role in nuclear medicine. It is therefore essential to make available broad information on practical production routes and optimal quality control for F-18 tracers, to achiev...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: IAEA
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Vienna : IAEA, 2021.
Colección:IAEA-TECDOC.
Temas:
Acceso en línea:Texto completo

MARC

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500 |a Description based upon print version of record. 
520 |a Since their clinical use initiation in the 1970's, Fluorine-18 (F-18) radiopharmaceuticals continue to play an important role in nuclear medicine. It is therefore essential to make available broad information on practical production routes and optimal quality control for F-18 tracers, to achieve the best possible products in high quantity and quality for clinical applications while fulfilling all regulatory requirements. This publication describes the chemical and biological properties of F-18 radiopharmaceuticals. This includes aspects relating to F-18 target production and radiofluorination methods, with focus on the applied techniques. The publication presents a disease oriented approach, describing F-18 radiopharmaceuticals, ranging from the physiological/biological aspects to dedicated radiopharmaceutical development approaches and provides readers with clear guidelines and methods for the production of F-18 radiopharmaceuticals. 
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650 7 |a Radiopharmaceuticals  |x Testing.  |2 fast  |0 (OCoLC)fst01088334 
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