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Green approaches in medicinal chemistry for sustainable drug design /

Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Banik, Bimal K. (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Amsterdam, Netherlands ; Cambridge, MA : Elsevier, [2020]
Colección:Advances in green and sustainable chemistry
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Intro
  • Green Approaches in Medicinal Chemistry for Sustainable Drug Design
  • Copyright
  • Contents
  • Contributors
  • Editor's biography
  • Preface
  • Part One: Green chemistry
  • Chapter 1: Green chemistry assisted synthesis of natural and synthetic compounds as anticancer agents
  • 1.1. Introduction
  • 1.2. Natural products as anticancer agents
  • 1.3. Synthetic compounds as anticancer agents
  • 1.4. Conclusion
  • References
  • Chapter 2: Antibacterial and antimicrobial coatings on metal substrates by cold spray technique: Present and future persp ...
  • 2.1. Introduction
  • 2.2. The need for the development of antibacterial and antimicrobial coatings
  • 2.3. The coating techniques
  • 2.4. Thermal spraying: Processes and techniques
  • 2.5. Cold spray: The process and its advantages
  • 2.6. Present status of the antibacterial and antimicrobial coating by cold spray
  • 2.7. Sustainability and cold spray technique
  • 2.8. Green aspects of cold spray
  • 2.9. Future prospects and concluding remarks
  • 2.10. Summary
  • References
  • Chapter 3: Graphene oxide nanosheets as sustainable carbocatalysts: Synthesis of medicinally important heterocycles
  • 3.1. Introduction
  • 3.2. Strategies for the synthesis of medicinally important heterocyclic scaffolds using GO and CMGs
  • 3.2.1. Synthesis of substituted pyrroles and related heterocycles using GO nanosheets
  • 3.2.2. Synthetic approaches for quinazoline derivatives
  • 3.2.3. Multicomponent approach for the synthesis of substituted pyridine derivatives
  • 3.2.4. Synthesis of benzothiazines, benzothiazoles, imidazoles, and benzimidazoles
  • 3.2.5. Synthesis of functionalized quinoxalines
  • 3.2.6. Synthesis of 4H-pyrans, coumarins, chromenes, flavones, and xanthenes
  • 3.2.7. Synthesis of pyrimidones
  • 3.2.8. Catalytic processes for the synthesis of 1,2,3-triazoles
  • References
  • Chapter 4: Sustainable green technologies for synthesis of potential drugs targeted toward tropical diseases
  • 4.1. Introduction
  • 4.2. Dose reduction through improved drug composition
  • 4.3. Green dose setting
  • 4.4. Reduction of cost through green chemistry
  • 4.5. Green chemistry in ARV therapy
  • 4.6. Green technology in malaria treatment
  • 4.7. Conclusion
  • References
  • Chapter 5: Clay-mediated synthesis of biologically active molecules: Green and sustainable approaches
  • 5.1. Introduction
  • 5.1.1. Green and sustainable approach
  • 5.1.1.1. Basic principles of green chemistry
  • 5.1.1.2. Basic green methods for chemical synthesis
  • Microwave-induced method
  • Sonication method
  • Biosynthetic method
  • 5.1.2. Clay minerals
  • 5.1.2.1. Classification of clay
  • 5.2. Clay-mediated synthesis of biologically active molecules
  • 5.2.1. Natural clay
  • 5.2.2. Montmorillonite K-10 clay
  • 5.2.3. Modified montmorillonite clay
  • 5.2.4. Modified montmorillonite K-10 clay
  • 5.2.5. Natural bentonite clay
  • 5.2.6. Modified bentonite clay
  • 5.2.7. Montmorillonite KSF clay