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KNOVEL_on1057284283 |
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20231027140348.0 |
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140514s2019 enka ob 001 0 eng |
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|a 1060184747
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|a 9781788012676
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|a (OCoLC)1057284283
|z (OCoLC)1060184747
|z (OCoLC)1061019468
|z (OCoLC)1081417830
|z (OCoLC)1098159844
|z (OCoLC)1099226428
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|a R857.P6
|b B56 2019
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|a TP248.65.P62
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|a SCI
|x 013040
|2 bisacsh
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|2 23
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|a 547/.7
|2 23
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|a UAMI
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245 |
0 |
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|a Biodegradable thermogels /
|c edited by Xian Jun Loh and David James Young.
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264 |
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1 |
|a London :
|b Royal Society of Chemistry,
|c [2019]
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300 |
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|a 1 online resource :
|b illustrations
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336 |
|
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|a text
|b txt
|2 rdacontent
|
337 |
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|a computer
|b c
|2 rdamedia
|
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|a online resource
|b cr
|2 rdacarrier
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490 |
1 |
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|a Biomaterials science series,
|x 2397-141X ;
|v no. 2
|
505 |
0 |
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|a Cover; Preface; Contents; Chapter 1 Thermogelling Polymers and Their History; 1.1 Introduction; 1.2 Synthesis; 1.3 Micellization and Thermogelling Properties; 1.3.1 Gelation Mechanism; 1.3.2 Kinetics of Micellization; 1.3.3 Formation of Micelles with Different Morphologies; 1.4 Pluronic Systems in the Biomedical Sciences; 1.4.1 Early Uses; 1.4.2 Wound Healing; 1.4.3 Drug Delivery; 1.5 Disadvantages of Pluronic Systems; 1.6 Modifications of Pluronic Copolymers; 1.6.1 Modified Pluronic Copolymers for Improved Mechanical Properties.
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|a 1.6.2 Modified Pluronic Copolymers for Improved Biodegradability1.7 Modern Applications of Pluronics; 1.8 Future Perspectives; References; Chapter 2 Thermogelling PLGA-based Copolymers; 2.1 History and Structures; 2.2 Synthesis; 2.3 Properties; 2.3.1 Reversible Sol-to-gel Transition; 2.3.2 Degradation; 2.3.3 Biocompatibility; 2.4 Applications; 2.4.1 Drug Release; 2.4.2 Gene Delivery; 2.4.3 Postoperative Adhesion Prevention; 2.5 Areas for Future Research; 2.6 Conclusions; References.
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|a Chapter 3 Polyester-based Biodegradable Thermogelling Systems as Emerging Materials for Therapeutic Applications3.1 Introduction; 3.2 Polyester-based Thermogelling Systems; 3.2.1 The Poly(lactic acid)-based Thermogelling Systems; 3.2.2 Polycaprolactone-based Thermogelling Systems; 3.2.3 Poly([R]-3-hydroxybutyrate)-based Thermogelling System; 3.2.4 Poly(glycerol sebacate)-based Thermogelling Systems; 3.3 Application of Polyester-based Thermogelling Systems; 3.3.1 Therapeutic Delivery; 3.3.2 Tissue Engineering; 3.4 Conclusion; Abbreviations; References.
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|a Chapter 4 Biodegradable Thermogelling Polymers for Drug Delivery4.1 Introduction; 4.2 Thermogelling Mechanism; 4.3 Mechanism of Drug Release in Thermogels; 4.4 Advantages and Disadvantages of Thermogelling Polymeric Materials Compared to Other Drug-delivery Methods; 4.5 Delivery of Insulin and Protein Drugs in the Treatment of Diabetes; 4.6 Adaptation of Thermogels for Biomedical Applications; 4.6.1 Selenium-containing Thermogels; 4.6.2 Matrix Metalloproteinase-sensitive Thermogelling Polymers; 4.7 Towards Understanding In-vivo Effectiveness of Polymeric Thermogel Drug Delivery.
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|a 4.7.1 Toxicological Aspects of the Use of Dextran Microspheres and Thermogelling Ethyl(hydroxyethyl) Cellulose as Nasal Drug-delivery Systems4.7.2 In-vivo Pharmacological Evaluations of an Antioxidant-loaded Biodegradable Thermogel; 4.8 Conclusion; References; Chapter 5 Injectable Thermogelling Polymers for Bone and Cartilage Tissue Engineering; 5.1 Introduction; 5.2 Scaffold Requirements for Bone and Cartilage Tissue Engineering; 5.3 Chemistry and Properties of Selected Injectable Thermogelling Scaffolds; 5.3.1 Totally Non-degradable Polymers; 5.3.2 Enzymatically Degradable Polymers.
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|a Biodegradable thermogels are a promising class of stimuli-responsive polymers. This book summarizes recent developments in thermogel research with a focus on synthesis and self-assembly mechanisms, gel biodegradability, and applications for drug delivery, cell encapsulation and tissue engineering.
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588 |
0 |
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|a Online resource; title from digital title page (viewed on November 14, 2018).
|
504 |
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|a Includes bibliographical references and index.
|
590 |
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|a Knovel
|b ACADEMIC - Chemistry & Chemical Engineering
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590 |
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|a Knovel
|b ACADEMIC - General Engineering & Project Administration
|
650 |
|
0 |
|a Polymers in medicine.
|
650 |
|
0 |
|a Polymers
|x Biotechnology.
|
650 |
|
6 |
|a Polymères en médecine.
|
650 |
|
6 |
|a Polymères
|x Biotechnologie.
|
650 |
|
7 |
|a SCIENCE
|x Chemistry
|x Organic.
|2 bisacsh
|
650 |
|
7 |
|a Polymers in medicine.
|2 fast
|0 (OCoLC)fst01070661
|
650 |
|
7 |
|a Polymers
|x Biotechnology.
|2 fast
|0 (OCoLC)fst01070596
|
700 |
1 |
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|a Loh, Xian Jun,
|e editor.
|
700 |
1 |
|
|a Young, David James,
|e editor.
|
776 |
0 |
8 |
|i Print version:
|z 1782629408
|z 9781782629405
|w (OCoLC)1036275771
|
830 |
|
0 |
|a Biomaterials science series ;
|v no. 2.
|
856 |
4 |
0 |
|u https://appknovel.uam.elogim.com/kn/resources/kpBT000003/toc
|z Texto completo
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938 |
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|a ProQuest Ebook Central
|b EBLB
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|a EBSCOhost
|b EBSC
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