Handbook of advanced chromatography/mass spectrometry techniques /
Handbook of Advanced Chromatography /Mass Spectrometry Techniques is a compendium of new and advanced analytical techniques that have been developed in recent years for analysis of all types of molecules in a variety of complex matrices, from foods to fuel to pharmaceuticals and more. Focusing on ar...
Clasificación: | Libro Electrónico |
---|---|
Otros Autores: | , |
Formato: | Electrónico eBook |
Idioma: | Inglés |
Publicado: |
Amsterdam :
Academic Press,
2017.
|
Temas: | |
Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Front Cover; Handbook of Advanced Chromatography/Mass Spectrometry Techniques; Dedication; Handbook of Advanced Chromatography/Mass Spectrometry TechniquesEdited by Michal HolčapekUniversity of Pardubice, Pardubice ... ; Copyright; Contents; List of Contributors; Preface; 1
- THEORY AND PRACTICE OF UHPLC AND UHPLC-MS; 1. INTRODUCTION; 2. BRIEF DESCRIPTION OF ULTRAHIGH-PRESSURE LIQUID CHROMATOGRAPHY AND HISTORICAL BACKGROUND; 2.1 INTEREST IN SMALL PARTICLES IN LIQUID CHROMATOGRAPHY; 2.2 INTEREST IN VERY HIGH PRESSURES IN LIQUID CHROMATOGRAPHY.
- 2.3 PRELIMINARY WORKS OF J.W. JORGENSON AND M.L. LEE IN ULTRAHIGH-PRESSURE LIQUID CHROMATOGRAPHY3. KINETIC COMPARISON OF ULTRAHIGH-PRESSURE LIQUID CHROMATOGRAPHY WITH OTHER EXISTING TECHNOLOGIES FOR FAST AND HIGH-RESOLUTION ... ; 3.1 BRIEF PRESENTATION OF THE ALTERNATIVE APPROACHES TO ULTRAHIGH-PRESSURE LIQUID CHROMATOGRAPHY; 3.2 BEST LIQUID CHROMATOGRAPHY APPROACH IN ISOCRATIC MODE-THEORY AND APPLICATIONS; 3.3 BEST LIQUID CHROMATOGRAPHY APPROACH IN GRADIENT MODE-THEORY AND APPLICATIONS; 4. PROBLEMS RELATED TO ULTRAHIGH-PRESSURE LIQUID CHROMATOGRAPHY.
- 4.1 THE NEED TO WORK WITH A DEDICATED INSTRUMENTATION4.2 THE NEED FOR SPECIFIC COLUMNS COMPATIBLE WITH ULTRAHIGH PRESSURES; 4.3 THE CHANGES IN SOLVENT PROPERTIES WITH PRESSURE; 5. METHOD TRANSFER FROM HIGH-PRESSURE LIQUID CHROMATOGRAPHY TO ULTRAHIGH-PRESSURE LIQUID CHROMATOGRAPHY; 5.1 THE RULES FOR ISOCRATIC MODE-THEORY AND APPLICATIONS; 5.2 THE RULES FOR GRADIENT MODE-THEORY AND APPLICATIONS; 6. FIELDS OF APPLICATION FOR ULTRAHIGH-PRESSURE LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY AND RELATED ISSUES.
- 6.1 ULTRAHIGH-PRESSURE LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY/MASS SPECTROMETRY FOR HIGH THROUGHPUT IN BIOANALYSIS6.2 HIGH RESOLUTION DRUG METABOLISM BY ULTRAHIGH-PRESSURE LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY USING QUADRUPOLE TIME-OF-FLIG ... ; 6.3 ULTRAHIGH-PRESSURE LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY FOR MULTIRESIDUE SCREENING; 6.4 ULTRAHIGH-PRESSURE LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY IN METABOLOMICS; 7. CONCLUSION/PERSPECTIVES; REFERENCES; FURTHER READING; 2
- ADVANCES IN HYDROPHILIC INTERACTION LIQUID CHROMATOGRAPHY; 1. INTRODUCTION.
- 2. COLUMNS FOR HYDROPHILIC INTERACTION LIQUID CHROMATOGRAPHY SEPARATIONS2.1 SILICA GEL AND HYBRID INORGANIC SORBENTS; 2.2 CHEMICALLY BONDED SILICA-BASED STATIONARY PHASES; 2.2.1 Amino, Amide Amino Acid, and Peptide Bonded Stationary Phases; 2.2.2 Diol, Polyethylene Glycol, Thioglycerol, Cyclodextrin, and Sugar Bonded Phases; 2.2.3 Polysuccinimide Bonded Stationary Phases; 2.2.4 Other Polymer Coated and Bonded Silica Stationary Phases; 2.2.5 Zwitterionic and Mixed-Mode Silica Stationary Phases; 2.3 AQUEOUS NORMAL-PHASE CHROMATOGRAPHY ON HYDROSILATED SILICA PHASES.