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Principles of fermentation technology /
The successful structure of the previous edition of Principles of Fermentation Technology has been retained in this third edition, which covers the key component parts of a fermentation process including growth kinetics, strain isolation and improvement, inocula development, fermentation media, ferm...
| Clasificación: | Libro Electrónico |
|---|---|
| Autores principales: | , , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Oxford, United Kingdom :
Butterworth-Heinemann is an imprint of Elsevier,
[2016]
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| Edición: | Third edition. |
| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Cover; Title Page; Copyright Page; Dedication; Contents; Acknowledgments; Chapter 1
- An introduction to fermentation processes; The range of fermentation processes; Microbial biomass; Microbial enzymes; Microbial metabolites; Recombinant products; Transformation processes; The chronological development of the fermentation industry; The component parts of a fermentation process; References; Chapter 2
- Microbial growth kinetics; Batch culture; Exponential phase; Deceleration and stationary phases; Continuous culture; Multistage systems; Feedback systems; Internal feedback; External feedback.
- Comparison of batch and continuous culture in industrial processesBiomass productivity; Metabolite productivity; Continuous brewing; Continuous culture and biomass production; Comparison of batch and continuous culture as investigative tools; Fed-batch culture; Variable volume fed-batch culture; Fixed volume fed-batch culture; Fed-batch culture at a constant specific growth rate; Cyclic fed-batch culture; Application of fed-batch culture; Examples of the use of fed-batch culture; References; Chapter 3
- The isolation and improvement of industrially important microorganisms.
- Isolation of industrially important microorganismsIsolation methods utilizing selection of the desired characteristic; Enrichment liquid culture; Enrichment cultures using solidified media; Isolation methods not utilizing selection of the desired characteristic-from the "Waksman platform" to the 1990s; Screening methods and high throughput screening; Return of natural products; Broadening the base of the discovery process and maximizing gene expression; Improvement of industrial microorganisms; Improvement of strains producing primary biosynthetic products.
- Selection of induced mutants synthesizing improved levels of primary metabolitesIsolation of Corynebacterium glutamicum and the role of permeability in the glutamate fermentation; Isolation of mutants that do not produce feedback inhibitors or repressors; Isolation of mutants that do not recognize the presence of inhibitors and repressors; The use of recombination systems for the improvement of primary metabolite production; Transduction, transformation, and protoplast fusion; Recombinant DNA technology.
- Postgenomic era-the influence of genomics, transcriptomics, and fluxomics on the improvement of primary metabolite producersApplication of genomics; Application of transcriptomics; Application of metabolic flux analysis and a systems biology approach; Improvement of strains producing secondary biosynthetic products; Isolation of mutants producing improved yields of secondary metabolites; The empirical approach; Use of directed selection in the isolation of improved secondary metabolite producers; Use of recombination systems for the improvement of secondary metabolite production.