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Green biocatalysis /

"This book describes the enzyme-driven syntheses of industrially important compounds and chiral intermediates for chemicals and pharmaceuticals. The chapters describe recent technological advances in enzymatic and microbial transformations and are written by internationally renowned scientists...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Patel, Ramesh N., 1942-
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Hoboken, NJ : John Wiley & Sons, 2016.
Temas:
Acceso en línea:Texto completo

MARC

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245 0 0 |a Green biocatalysis /  |c edited by Ramesh N. Patel. 
264 1 |a Hoboken, NJ :  |b John Wiley & Sons,  |c 2016. 
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520 |a "This book describes the enzyme-driven syntheses of industrially important compounds and chiral intermediates for chemicals and pharmaceuticals. The chapters describe recent technological advances in enzymatic and microbial transformations and are written by internationally renowned scientists and professors. The synthesis of industrially important molecules is described from the starting substrate to the final product and includes detailed mechanisms. This book addresses the use of various types of reactions catalyzed by microbial cells or enzymes derived from microbes in the production of industrially useful compounds and a variety of drugs. The production of chiral alcohols, amines, unnatural amino acids, esters, carboxylic acids, epoxides, hydroxylated compounds and drug metabolites as well as recent advances in enzyme catalyzed acylation, dehalogenation, esterification, oxidation-reduction, transamination, deamination, C-N, C-C, C-O bond formation, Baeyer-Villegar reaction and aldol as well as acyloin condensation reactions are covered. Cutting-edge topics such as directed evolution by gene shuffling and enzyme engineering to improve biocatalysts will be presented. Enzyme immobilization and reusability studies and enzymatic protection and deprotection are addressed as well"--  |c Provided by publisher. 
504 |a Includes bibliographical references and index. 
588 0 |a Print version record and CIP data provided by publisher. 
505 0 |6 880-01  |a Title Page; Copyright Page; Contents; Preface; About the Editor; Contributors ; Chapter 1 Biocatalysis and Green Chemistry ; 1.1 INTRODUCTION TO SUSTAINABLE DEVELOPMENT AND GREEN CHEMISTRY; 1.2 GREEN CHEMISTRY METRICS; 1.3 ENVIRONMENTAL IMPACT AND SUSTAINABILITY METRICS; 1.4 SOLVENTS; 1.5 THE ROLE OF CATALYSIS; 1.6 BIOCATALYSIS AND GREEN CHEMISTRY; 1.7 EXAMPLES OF GREEN BIOCATALYTIC PROCESSES; 1.7.1 A Chemoenzymatic Process for Pregabalin; 1.7.2 A Three-Enzyme Process for Atorvastatin Intermediate ; 1.7.3 Enzymatic Synthesis of Sitagliptin. 
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650 0 |a Enzymes  |x Biotechnology. 
650 0 |a Biocatalysis. 
650 0 |a Green chemistry. 
650 2 |a Biocatalysis 
650 6 |a Enzymes  |x Biotechnologie. 
650 6 |a Biocatalyse. 
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700 1 |a Patel, Ramesh N.,  |d 1942- 
776 0 8 |i Print version:  |t Green biocatalysis.  |d Hoboken, New Jersey : John Wiley & Sons, 2016  |z 9781118822296  |w (DLC) 2015047535 
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880 8 |6 505-01/(S  |a 3.7 INVERSION OF ENANTIOSELECTIVITY DRAMATICALLY IMPROVES CATALYTIC ACTIVITY3.8 FUTURE PROSPECTS; REFERENCES; Chapter 4 Green Processes for the Synthesis of Chiral Intermediates for the Development of Drugs ; 4.1 INTRODUCTION; 4.2 SAXAGLIPTIN: ENZYMATIC SYNTHESIS OF (S)-N-BOC-3-HYDROXYADAMANTYLGLYCINE; 4.3 SITAGLIPTIN: ENZYMATIC SYNTHESIS OF CHIRAL AMINE; 4.4 VANLEV: ENZYMATIC SYNTHESIS OF (S)-6-HYDROXYNORLEUCINE ; 4.5 VANLEV: ENZYMATIC SYNTHESIS OF ALLYSINE ETHYLENE ACETAL; 4.6 VANLEV: ENZYMATIC SYNTHESIS OF THIAZEPINE; 4.7 TIGEMONAM: ENZYMATIC SYNTHESIS OF (S)-β-HYDROXYVALINE. 
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