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|a Semiconducting silicon nanowires for biomedical applications /
|c edited by Jeffrey L. Coffer.
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|a Cambridge :
|b Woodhead Publishing,
|c 2014.
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|a 1 online resource
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|a text
|b txt
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|a computer
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|a Woodhead Publishing Series in Biomaterials ;
|v no. 73
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|a Print version record.
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|a Includes bibliographical references and index.
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|a Biomedical applications have benefited greatly from the increasing interest and research into semiconducting silicon nanowires. This book reviews the fabrication, properties, and applications of this emerging material. The book begins by reviewing the basics, as well as the growth, characterization, biocompatibility, and surface modification, of semiconducting silicon nanowires. It goes on to focus on silicon nanowires for tissue engineering and delivery applications, including cellular binding and internalization, orthopedic tissue scaffolds, mediated differentiation of stem cells, and silicon nanoneedles for drug delivery. Finally, it highlights the use of silicon nanowires for detection and sensing. These chapters explore the fabrication and use of semiconducting silicon nanowire arrays for high-throughput screening in the biosciences, neural cell pinning on surfaces, and probe-free platforms for biosensing. --
|c Provided by publisher.
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|a Cover; Semiconducting Silicon Nanowires for Biomedical Applications; Copyright; Contents; Contributor contact details; Woodhead Publishing Series in Biomaterials; Foreword; Part I Introduction to silicon nanowires for biomedical applications; 1 Overview of semiconducting silicon nanowires for biomedical applications; 1.1 Introduction; 1.2 Origins of silicon nanowires; 1.3 The structure of this book; 1.4 Conclusion; 1.5 References; 2 Growth and characterization of semiconducting silicon nanowires for biomedical applications; 2.1 Introduction; 2.2 Synthesis methods for silicon nanowires (SiNWs)
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|a 2.3 Characterization methods2.4 Synthesis of semiconductor SiNWs by the chemical vapor deposition (CVD) method; 2.5 Conclusion; 2.6 Future trends; 2.7 Sources of further information and advice; 2.8 References; 3 Surface modification of semiconducting silicon nanowires for biosensing applications; 3.1 Introduction; 3.2 Methods for fabricating silicon nanowires (SiNWs); 3.3 Chemical activation/passivation of SiNWs; 3.4 Modification of native oxide layer; 3.5 Modification of hydrogen-terminated silicon nanowires (H-SiNW); 3.6 Sitespecific immobilization strategy of biomolecules on SiNWs.
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|a 3.7 Control of nonspecific interactions3.8 Conclusion; 3.9 References; 4 Biocompatibility of semiconducting silicon nanowires; 4.1 Introduction; 4.2 In vitro biocompatibility of silicon nanowires (SiNWs); 4.3 In vivo biocompatibility of SiNWs; 4.4 Methodology issues; 4.5 Future trends; 4.6 Conclusion; 4.7 References; Part II Silicon nanowires for tissue engineering and delivery applications; 5 Functional semiconducting silicon nanowires for cellular binding and internalization; 5.1 Motivation: developing a nano-bio model system for rational design in nanomedicine.
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|a 5.2 Methods: non-linear optical characterization and surface functionalization of silicon nanowires (SiNWs)5.3 Applications: in vivo imaging and in vitro cellularinteraction of functional SiNWs; 5.4 Conclusions and future trends; 5.5 References; 6 Functional semiconducting silicon nanowires and their composites as orthopedic tissue scaffolds; 6.1 Introduction; 6.2 Nanowire surface etching processes to induce biomineralization; 6.3 Nanowire surface functionalization strategies to induce biomineralization; 6.4 Construction of silicon nanowire (SiNW)-polymer scaffolds: mimicking trabecular bone.
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|a 6.5 The role of SiNW orientation in cellular attachment, proliferation and differentiation in the nanocomposite6.6 Conclusions and future trends; 6.7 Acknowledgement; 6.8 References; 7 Mediated differentiation of stem cells by engineered semiconducting silicon nanowires; 7.1 Introduction; 7.2 Methods for fabricating silicon nanowires (SiNWs); 7.3 Regulated differentiation for human mesenchymal stem cells (hMSCs); 7.4 SiNWs fabricated by the electroless metal deposition (EMD) method and their controllable spring constants; 7.5 Mediated differentiation of stem cells by engineered SiNWs.
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|a Knovel
|b ACADEMIC - Biochemistry, Biology & Biotechnology
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|a Nanowires.
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|a Biomedical materials.
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|a Biomedical materials
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|a Coffer, Jeffery,
|e editor.
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|i Print version:
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|a Woodhead Publishing series in biomaterials ;
|v no. 73.
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