Sequence-specific DNA binding agents /

The binding of antibiotics and drugs to DNA is a fast developing area of research with important applications in medicine, particularly the treatment of cancer. Sequence-specific DNA Binding Agents uniquely discusses key aspects of this topic, providing a novel perspective on the subject. Written by...

Descripción completa

Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Waring, Michael J.
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Cambridge : RSC Pub., ©2006.
Colección:RSC biomolecular sciences.
Temas:
DNA-drug interactions.
DNA-binding proteins.
Gene targeting.
Drug targeting.
Chemotherapy.
DNA-Binding Proteins > therapeutic use
Chemistry, Pharmaceutical > methods
DNA > drug effects
DNA > metabolism
DNA-Binding Proteins > chemistry
DNA-Binding Proteins > metabolism
DNA-Binding Proteins
Gene Targeting
Drug Delivery Systems
Drug Therapy
Interactions ADN-médicament.
Protéines de liaison à l'ADN.
Gènes > Ciblage.
Médicaments > Ciblage.
Chimiothérapie.
Acceso en línea:Texto completo
Tabla de Contenidos:
  • DNA recognition by triple helix formation / David A. Rusling, Tom Brown, and Keith R. Fox
  • Interfacial inhibitors of human topoisomerase I / Christophe Marchand and Yves Pommier
  • Diversity of topoisomerase I inhibitors for cancer chemotherapy / Nathalie Dias and Christian Bailly
  • Slow DNA binding / L. Marcus Wilhelmsson, Per Lincoln, and Bengt Nordén
  • DNA gene targeting using Peptide Nucleic Acid (PNA) / Peter E. Nielsen
  • Actinomycin D : sixty years of progress in characterizing a sequence-selective DNA-binding agent / David E. Graves
  • Thermal denaturation of drug-DNA complexes : tools and tricks / Jonathan B. Chaires and Xiaochun Shi
  • Computer simulations of drug-DNA interactions : a personal journey / Federico Gago
  • The discovery of G-quadruplex telomere targeting drugs / Stephen Neidle
  • The mechanism of action of telomestatin, a G-quadruplex-interactive compound / Daekyu Sun and Laurence H. Hurley
  • Structural features of the specific interactions between nucleic acids and small organic molecules / Alexander Serganov and Dinshaw J. Patel.

Ejemplares similares