Microbial glycobiology : structures, relevance and applications /

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This book presents in an easy-to-read format a summary of the important central aspects of microbial glycobiology, i.e. the study of carbohydrates as related to the biology of microorganisms. Microbial glycobiology represents a multidisciplinary and emerging area with implications for a range of bas...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Moran, Anthony P., Holst, Otto, Brennan, Patrick J. Ph. D., Itzstein, Mark von
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Amsterdam ; Boston : Academic Press/Elsevier, Ã2009.
Edición:1st ed.
Temas:
Pathogenic microorganisms > Identification.
Glycomics.
Carbohydrates.
Glucides.
Bacteria > chemistry
Carbohydrates
Glycomics
Glycomics > methods
Microbiological Techniques
Glycomique.
carbohydrate.
Pathogenic microorganisms.
Glykobiologie
field guides.
Field guides.
Guides d'identification.
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Part I. Microbial glycolipids, glyoproteins and glycopolymers¨1. Overview of the glycosylated components of the bacterial cell wallȨ2. Bacterial cell wall envelope peptidoglycanȨ3. Core oligosaccharide and lipid A components of lipopolysaccharidesȨ4. O-Specific polysaccharides of Gram-negative bacteriaȨ5. Teichoic acids, lipoteichoic acids, and related cell wall glycopolymers of Gram-positive bacteriaȨ6. Bacterial capsular polysaccharides and exopolysaccharidesȨ7. Bacterial surface layer glycoproteins and "non-classical" secondary cell wall polymersȨ8. Glycosylation of bacterial and archaeal flagellinsȨ9. Glycosylated components of the mycobacterial cell wall: structure and functionȨ10. Glycoconjugate structure and function in fungal cell wallsȨ11. Cytoplasmic carbohydrate molecules: trehalose and glycogenȨ12. Glycosylated compounds of parasitic protozoaȨ13. Analytical approaches towards the structural characterization of microbial wall glycopolymersȨ14. Single-molecule characterization of microbial polysaccharidesȨ15. Viral surface glycoproteins in carbohydrate recognition: structure and modelingÈPart II. Synthesis of microbial glycosylated components; A. Biosynthesis and biosynthetic processes¨16. Biosynthesis of bacterial peptidoglycanȨ17. Biosynthesis and membrane assembly of lipid AȨ18. Biosynthesis of O-antigen chains and assemblyȨ19. Biosynthesis of cell wall teichoic acid polymersȨ20. Biosynthesis and assembly of capsular polysaccharidesȨ21. Biosynthesis of the mycobacterial cell envelope componentsȨ22. Biosynthesis of fungal and yeast glycansÈB. Chemical synthesisȨ23. Chemical synthesis of bacterial lipid AȨ24. Chemical synthesis of the core oligosaccharide of bacterial lipopolysaccharideȨ25. Chemical synthesis of lipoichoic acid and derivativesȨ26. Chemical synthesis of parasitic glycoconjugates and phosphoglycans¨Part III. Microbe-host glycosylated interactionsȨ27. Bacterial lectin-like interactions in cell recognition and adhesionȨ28. Lectin-like interactions in virus-cell recognition: human immunodeficiency virus and C-type lectin interactionsȨ29. Sialic acid-specific microbial lectinsÈȨ30. Bacterial toxins and their carbohydrate receptors at the host-pathogen interfaceȨ31. Toll-like receptor recognition of lipoglycans, glycolipids and lipopeptidesȨ32. NOD receptor recognition of peptidoglycanȨ33. Microbial interaction with mucus and mucinsȨ34. Mannose-fucose recognition by DC-SIGNȨ35. Host surfactant proteins in microbial recognitionȨ36. T-cell recognition of microbial lipoglycans and glycolipids¨Part IV. Biological relevance of microbial glycosylated components; A. Environmental relevanceȨ37. Extracellular polymeric substances in microbial biofilmsȨ38. Physico-chemical properties of microbial glycopolymersȨ39. Microbial biofilm-related polysaccharides in biofouling and corrosionȨ40. Microbial glycosylated components in plant diseaseÈÈB. Medical relevanceȨ41. Antigenic variation of microbial surface glycosylated moleculesȨ42. Phase variation of bacterial surface glycosylated molecules in immune evasionȨ43. Molecular mimicry of host glycosylated structures by bacteriaȨ44. Role of microbial glycosylation in host cell invasion¨Part V. Biotechnological and medical applicationsȨ45. Exopolysaccharides produced by lactic acid bacteria in food and probiotic applicationsȨ46. Industrial exploitation by genetic engineering of bacterial glycosylation systemsȨ47. Glycomimetics as inhibitors in anti-infection therapyȨ48. Bacterial polysaccharide vaccines: glycogonjugates and peptide-mimeticsȨ49. Immunomodulation by zwitterionic polysaccharidesȨ50. Future potential of glycomics in microbiology and infectious diseasesÈ

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