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Drug design : cutting edge approaches /

Pharmaceutical research draws on increasingly complex techniques to solve the challenges of drug design. Bringing together a number of the latest informatics techniques, this book looks at modelling and bioinformatic strategies; structural genomics and X-ray crystallography; virtual screening; lead...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Flower, Darren R.
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Cambridge, UK : Royal Society of Chemistry, ©2002.
Colección:Special publication (Royal Society of Chemistry (Great Britain)) ; no. 279.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Molecular informatics : sharpening drug design's cutting edge
  • High-throughput X-ray crystallography for drug discovery
  • Trawling the genome for G protein-coupled receptors : the importance of integrating bioinformatic approaches
  • Virtual screening of virtual libraries : an efficient startegy for lead generation
  • Virtual techniques for lead optimisation
  • The impact of physical organic chemistry on the control of drug-like properties
  • Mutagenesis and modelling highlight the critical nature of the TM2-loop-TM3 region of biogenic amine GPCRs
  • Computational vaccine design.