The Construction of Analogy-Based Research Programs : the Lock-and-Key Analogy in 20th Century Biochemistry.

When the German chemist Emil Fischer presented his key-lock hypothesis in 1899, his analogy to describe the molecular relationship between enzymes and substrates quickly gained vast influence and provided future generations of scientists with a tool to investigate the relation between chemical struc...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Mertens, Rebecca
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Bielefeld : Transcipt Verlag, 2019.
Colección:Science studies.
Temas:
1700-1799
History.
History of Science.
Medicine.
Science > Social aspects.
Life sciences.
Science > Philosophy.
Biochemistry.
Analogy.
Research Program.
Molecular biology.
Mathematical models.
Medicine > History > 18th century.
Biochemical Phenomena
Research > history
Models, Theoretical
History, 19th Century
History, 18th Century
History
Medicine
Biological Science Disciplines
Biochemistry
Molecular Biology
Histoire.
Médecine.
Sciences > Aspect social.
Sciences de la vie.
Biochimie.
Analogie (Philosophie)
Biologie moléculaire.
Modèles mathématiques.
Médecine > Histoire > 19e siècle.
Médecine > Histoire > 18e siècle.
history (discipline)
medicines (material)
biological sciences.
biochemistry.
analogy.
molecular biology.
mathematical models.
HISTORY > General.
HISTORY / General
Acceso en línea:Texto completo
Descripción
Sumario:When the German chemist Emil Fischer presented his key-lock hypothesis in 1899, his analogy to describe the molecular relationship between enzymes and substrates quickly gained vast influence and provided future generations of scientists with a tool to investigate the relation between chemical structure and biological specificity. Rebecca Mertens explains the appeal of the lock-and-key analogy by its role in model building and in the construction of long-term, cross-generational research programs. She argues that a crucial feature of these research programs, namely ascertaining the continuity of core ideas and concepts, is provided by a certain way of analogy-based modelling.
Descripción Física:1 online resource (225 pages)
ISBN:383944442X
9783839444429
Acceso:Legal Deposit;

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