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The quest for the cure : the science and stories behind the next generation of medicines /
After more than fifty years of blockbuster drug development, skeptics are beginning to fear we may be reaching the end of drug discovery to combat major diseases. In this engaging book, Brent Stockwell, a leading researcher in the exciting new science of chemical biology, describes this dilemma and...
| Clasificación: | Libro Electrónico |
|---|---|
| Autor principal: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
New York :
Columbia University Press,
©2011.
|
| Temas: | |
| Acceso en línea: | Texto completo |
MARC
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| 100 | 1 | |a Stockwell, Brent R., |e author. | |
| 245 | 1 | 4 | |a The quest for the cure : |b the science and stories behind the next generation of medicines / |c Brent R. Stockwell. |
| 260 | |a New York : |b Columbia University Press, |c ©2011. | ||
| 300 | |a 1 online resource (xviii, 265 pages) : |b illustrations (some color) | ||
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| 504 | |a Includes bibliographical references and index. | ||
| 505 | 0 | |a The drug discovery crisis -- A new science of molecules -- The birth of the first cancer drugs -- A new company creating drug combinations -- The undruggable RAS protein -- The druggable genome -- Peering inside proteins -- The nature of interactions between proteins -- From protein-protein interactions to personalized medicines -- A revolution in peptide synthesis -- A vast array of drug candidates -- Moving outside the small molecule box -- Accelerating the arrival of next-generation drugs. | |
| 520 | |a After more than fifty years of blockbuster drug development, skeptics are beginning to fear we may be reaching the end of drug discovery to combat major diseases. In this engaging book, Brent Stockwell, a leading researcher in the exciting new science of chemical biology, describes this dilemma and the powerful techniques that may bring drug research into the twenty-first century. Filled with absorbing stories of breakthroughs, the book begins with the scientific achievements of the twentieth century that led to today's drug innovations. We learn how the invention of mustard gas in. | ||
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| 650 | 2 | 2 | |a Proteins |x metabolism |
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| 650 | 6 | |a Médicaments |x Conception. | |
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| 650 | 7 | |a Proteins |x Metabolism. |2 fast |0 (OCoLC)fst01079741 | |
| 776 | 0 | 8 | |i Print version: |a Stockwell, Brent R. |t Quest for the cure. |d New York : Columbia University Press, ©2011 |w (DLC) 2010053573 |
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