Smart external stimulus-responsive nanocarriers for drug and gene delivery /

The concept of smart drug delivery vehicles involves designing and preparing a nanostructure (or microstructure) that can be loaded with a cargo, this can be a therapeutic drug, a contrast agent for imaging, or a nucleic acid for gene therapy. The nanocarrier serves to protect the cargo from degrada...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autores principales: Karimi, Mahdi (Scientist) (Autor), Zangabad, Parham Sahandi (Autor), Ghasemi, Amir (Autor), Hamblin, Michael R. (Autor)
Formato: Electrónico eBook
Idioma:Inglés
Publicado: San Rafael [California] (40 Oak Drive, San Rafael, CA, 94903, USA) : Morgan & Claypool Publishers, [2015]
Colección:IOP (Series). Release 2.
IOP concise physics.
Temas:
Nanomedicine.
Drug delivery systems.
Gene therapy.
Nanomedicine > methods.
Drug Delivery Systems.
Drug Therapy > methods.
Gene Therapy > methods.
Nanostructures > therapeutic use.
TECHNOLOGY & ENGINEERING / Biomedical.
Biomedical Engineering.
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Preface
  • Acknowledgments
  • Author biography
  • 1. Introduction
  • 2. Light-sensitive nanocarriers
  • 2.1. Introduction
  • 2.2. Photo-sensitive nanoparticle-based carriers
  • 2.3. Drug release via electrostatic assembly/disassembly (reversed surface charge)
  • 2.4. Chromophore (or photosensitizer)-activated drug release
  • 2.5. Photo-thermal-based drug release
  • 2.6. Photo-sensitive caging/uncaging based on photolabile protecting groups
  • 2.7. Photo-reduction-triggered drug release
  • 3. Temperature-sensitive nanocarriers
  • 3.1. Introduction
  • 3.2. LCST/UCST behavior
  • 3.3. Thermo-responsive nanocarriers
  • 3.4. Modulation of phase transition temperature in thermo-responsive nanoparticles
  • 3.5. Sustained drug release by hydrophobic hydrogels
  • 3.6. Cancer therapy via thermo-responsive nanocarriers
  • 3.7. Temperature-responsive gene delivery systems
  • 3.8. Thermo-sensitive co-delivery systems for cancer therapy
  • 3.9. Temperature in photothermal-responsive micro/nano-systems
  • 4. Magnetic-responsive nanocarriers
  • 4.1. Introduction
  • 4.2. Magnetic-responsive particles for drug delivery
  • 4.3. Magnetic-responsive particles for gene delivery
  • 5. Ultrasound-responsive nanocarriers
  • 5.1. Introduction
  • 5.2. Composition and structure of microbubbles
  • 5.3. Ultrasound-responsive materials in drug delivery
  • 5.4. Ultrasound-responsive materials in gene delivery
  • 6. Electrical and mechanical-responsive nanocarriers
  • 6.1. Introduction
  • 6.2. Electric field-sensitive polymers
  • 6.3. Mechanical-responsive nanomaterials
  • 7. Nanotoxicology and future scope for smart nanoparticles.

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