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Diabetes systems biology : quantitative methods for understanding beta-cell dynamics and function /

Diabetes Systems Biology provides senior undergraduate students and junior scientists, interested in diabetes systems biology, with a tool to learn more about the mathematical models and methods used to understand macroscopically and microscopically beta-cell behaviour in health and disease. The boo...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Khadra, Anmar, 1974- (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Bristol [England] (Temple Circus, Temple Way, Bristol BS1 6HG, UK) : IOP Publishing, [2020]
Colección:Biophysical Society-IOP series.
IOP ebooks. 2020 collection.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • 1. Introduction / Anmar Khadra
  • part I. Beta-cell function. 2. An introduction to beta cell electrophysiology and modeling / Leslie S. Satin, Margaret Watts and Arthur S. Sherman
  • 3. Recent advances in mathematical modeling and statistical analysis of exocytosis in endocrine cells / Morten Gram Pedersen, Francesco Montefusco, Alessia Tagliavini and Giuliana Cortese
  • part II. Modeling islet biology. 4. Islet architecture / Junghyo Jo
  • 5. Intra-islet network / Junghyo Jo and Margaret Watts
  • 6. The role of islet cell network in insulin secretion / I. Johanna Stamper, Nathaniel Wolanyk and Xujing Wang
  • part III. Insulin release in health and disease. 7. Insulin release in health and disease / Chiara Dalla Man and Morten Gram Pedersen
  • part IV. Autoimmune type 1 diabetes. 8. Applying systems biology to the genetics of age-of-onset dependent heterogeneity in type 1 diabetes / Shouguo Gao, Nathaniel Wolanyk, Soumitra Ghosh and Xujing Wang
  • 9. Immune-cell dynamics in type 1 diabetes / Hassan Jamaleddine and Anmar Khadra
  • part V. Diabetes implications on kidneys. 10. Diabetes implications on kidneys / Anita T. Layton and Rui Hu.