Diabetes systems biology : quantitative methods for understanding beta-cell dynamics and function /

Diabetes Systems Biology provides senior undergraduate students and junior scientists, interested in diabetes systems biology, with a tool to learn more about the mathematical models and methods used to understand macroscopically and microscopically beta-cell behaviour in health and disease. The boo...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Khadra, Anmar, 1974- (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Bristol [England] (Temple Circus, Temple Way, Bristol BS1 6HG, UK) : IOP Publishing, [2020]
Colección:Biophysical Society-IOP series.
IOP ebooks. 2020 collection.
Temas:
Diabetes > Mathematical models.
Systems biology > Mathematical models.
Pancreatic beta cells > Mathematical models.
Quantitative research > Methodology.
Diabetes Mellitus.
Systems Biology.
Insulin-Secreting Cells.
Evaluation Studies as Topic.
Models, Theoretical.
Biomedical engineering.
SCIENCE / Life Sciences / Biophysics.
Acceso en línea:Texto completo

MARC

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245 0 0 |a Diabetes systems biology :  |b quantitative methods for understanding beta-cell dynamics and function /  |c edited by Anmar Khadra. 
246 3 0 |a Quantitative methods for understanding beta-cell dynamics and function. 
264 1 |a Bristol [England] (Temple Circus, Temple Way, Bristol BS1 6HG, UK) :  |b IOP Publishing,  |c [2020] 
300 |a 1 online resource (various pagings) :  |b illustrations (some color). 
336 |a text  |2 rdacontent 
337 |a electronic  |2 isbdmedia 
338 |a online resource  |2 rdacarrier 
490 1 |a Biophysical Society-IOP series 
490 1 |a IOP ebooks. [2020 collection] 
500 |a "Version: 20201201"--Title page verso. 
504 |a Includes bibliographical references. 
505 0 |a 1. Introduction / Anmar Khadra -- part I. Beta-cell function. 2. An introduction to beta cell electrophysiology and modeling / Leslie S. Satin, Margaret Watts and Arthur S. Sherman -- 3. Recent advances in mathematical modeling and statistical analysis of exocytosis in endocrine cells / Morten Gram Pedersen, Francesco Montefusco, Alessia Tagliavini and Giuliana Cortese -- part II. Modeling islet biology. 4. Islet architecture / Junghyo Jo -- 5. Intra-islet network / Junghyo Jo and Margaret Watts -- 6. The role of islet cell network in insulin secretion / I. Johanna Stamper, Nathaniel Wolanyk and Xujing Wang -- part III. Insulin release in health and disease. 7. Insulin release in health and disease / Chiara Dalla Man and Morten Gram Pedersen -- part IV. Autoimmune type 1 diabetes. 8. Applying systems biology to the genetics of age-of-onset dependent heterogeneity in type 1 diabetes / Shouguo Gao, Nathaniel Wolanyk, Soumitra Ghosh and Xujing Wang -- 9. Immune-cell dynamics in type 1 diabetes / Hassan Jamaleddine and Anmar Khadra -- part V. Diabetes implications on kidneys. 10. Diabetes implications on kidneys / Anita T. Layton and Rui Hu. 
520 3 |a Diabetes Systems Biology provides senior undergraduate students and junior scientists, interested in diabetes systems biology, with a tool to learn more about the mathematical models and methods used to understand macroscopically and microscopically beta-cell behaviour in health and disease. The book introduces readers to the quantitative methods used to examine beta-cell dynamics, islet biology and architecture, as well as diabetes etiology and implications. The goal is to allow junior researchers in the fields of mathematical biology and biophysics to obtain a broad understanding of these quantitative methods, and guide them into taking the first steps into the field of diabetes systems biology. At the end of each chapter, several problem-solving exercises (that require both analytical and computational skills) are provided for the readers to help them become more proficient in this field. Part of Biophysical Society-IOP series. 
521 |a Senior and first/second year graduate students and junior researchers in diabetes systems biology, physiology and biological mathematical modelling. 
530 |a Also available in print. 
538 |a Mode of access: World Wide Web. 
538 |a System requirements: Adobe Acrobat Reader, EPUB reader, or Kindle reader. 
545 |a Anmar Khadra is an associate professor in the Department of Physiology and associate member of the Department of Physics and Department of Mathematics and Statistics at McGill University, Montreal, Canada. He is the co-director of the Centre for Applied Mathematics in Bioscience and Medicine at the university. 
588 0 |a Title from PDF title page (viewed on January 14, 2021). 
650 0 |a Diabetes  |x Mathematical models. 
650 0 |a Systems biology  |x Mathematical models. 
650 0 |a Pancreatic beta cells  |x Mathematical models. 
650 0 |a Quantitative research  |x Methodology. 
650 1 2 |a Diabetes Mellitus. 
650 1 2 |a Systems Biology. 
650 1 2 |a Insulin-Secreting Cells. 
650 1 2 |a Evaluation Studies as Topic. 
650 2 2 |a Models, Theoretical. 
650 7 |a Biomedical engineering.  |2 bicssc 
650 7 |a SCIENCE / Life Sciences / Biophysics.  |2 bisacsh 
700 1 |a Khadra, Anmar,  |d 1974-  |e editor. 
710 2 |a Institute of Physics (Great Britain),  |e publisher. 
776 0 8 |i Print version:  |z 9780750337373  |z 9780750337403 
830 0 |a Biophysical Society-IOP series. 
830 0 |a IOP ebooks.  |p 2020 collection. 
856 4 0 |u https://iopscience.uam.elogim.com/book/978-0-7503-3739-7  |z Texto completo 

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