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Single-particle cryo-EM of biological macromolecules /

This edited book is written for students, postdocs and established investigators who want to enter the field of single-particle cryo-EM. This is a recently developed method to determine high-resolution structures of biological macromolecules. A major strength is the fact that cryo-EM does not requir...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autores principales: Glaeser, Robert M. (Autor), Nogales, Eva (Autor), Chiu, Wah (Autor)
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Bristol [England] (Temple Circus, Temple Way, Bristol BS1 6HG, UK) : IOP Publishing, [2021]
Colección:IOP (Series). Release 21.
Biophysical Society-IOP series.
IOP ebooks. 2021 collection.
Temas:
Acceso en línea:Texto completo
Descripción
Sumario:This edited book is written for students, postdocs and established investigators who want to enter the field of single-particle cryo-EM. This is a recently developed method to determine high-resolution structures of biological macromolecules. A major strength is the fact that cryo-EM does not require prior crystallization of protein complexes. It is especially well suited for larger complexes and molecular machines. This book provides a comprehensive, accessible and authoritative introduction to the field. It covers all necessary background, ranging from the underlying concepts to practical aspects such as specimen preparation, data collection, data analysis, and the final validation of results.
Notas:"Version: 20210205"--Title page verso.
Descripción Física:1 online resource (various pagings) : illustrations (some color).
Also available in print.
Público:Beginning scientists in academia, pharma, and biotech.
Bibliografía:Includes bibliographical references.
ISBN:9780750330398
9780750330381