External field and radiation stimulated breast cancer nanotheranostics /
Nano drug-delivery systems responding to cellular local stimuli, such as pH, temperature, reductive agent's activation, i.e. enzymes, could effectively provide passive-mode desirable release but fail in disease treatment following the biological rhythms of brain tumor. Undoubtedly, physical sti...
Clasificación: | Libro Electrónico |
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Otros Autores: | , |
Formato: | Electrónico eBook |
Idioma: | Inglés |
Publicado: |
Bristol [England] (Temple Circus, Temple Way, Bristol BS1 6HG, UK) :
IOP Publishing,
[2019]
|
Colección: | IOP (Series). Release 6.
IOP expanding physics. IPEM-IOP series in physics and engineering in medicine and biology. |
Temas: | |
Acceso en línea: | Texto completo |
MARC
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024 | 7 | |a 10.1088/2053-2563/ab2907 |2 doi | |
035 | |a (CaBNVSL)thg00979555 | ||
035 | |a (OCoLC)1122753559 | ||
040 | |a CaBNVSL |b eng |e rda |c CaBNVSL |d CaBNVSL | ||
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072 | 7 | |a SCI009000 |2 bisacsh | |
082 | 0 | 4 | |a 616.99449 |2 23 |
245 | 0 | 0 | |a External field and radiation stimulated breast cancer nanotheranostics / |c edited by Nanasaheb D. Thorat and Joanna Bauer. |
264 | 1 | |a Bristol [England] (Temple Circus, Temple Way, Bristol BS1 6HG, UK) : |b IOP Publishing, |c [2019] | |
300 | |a 1 online resource (various pagings) : |b illustrations (chiefly color). | ||
336 | |a text |2 rdacontent | ||
337 | |a electronic |2 isbdmedia | ||
338 | |a online resource |2 rdacarrier | ||
490 | 1 | |a [IOP release 6] | |
490 | 1 | |a IOP expanding physics, |x 2053-2563 | |
490 | 1 | |a IPEM-IOP series in physics and engineering in medicine and biology | |
500 | |a "Version: 20190901"--Title page verso. | ||
504 | |a Includes bibliographical references. | ||
505 | 0 | |a 1. Introduction to external field stimulation modalities -- 1.1. Introduction -- 1.2. External field stimulation modalities -- 1.3. External field stimulation modalities for cancer theranostics -- 1.4. Conclusion | |
505 | 8 | |a 2. Physically responsive nanostructures in breast cancer theranostics -- 2.1. Introduction -- 2.2. Light-responsive systems -- 2.3. Magnetically responsive systems -- 2.4. Ultrasonic responsive system -- 2.5. Ionizing radiation triggered system -- 2.6. Future perspective | |
505 | 8 | |a 3. Externally/physically stimulated breast cancer nanomedicine 3-1 -- 3.1. Introduction -- 3.2. External/physical nanomedicine for breast cancers -- 3.3. Conclusion and future scope | |
505 | 8 | |a 4. Magnetically stimulated breast cancer nanomedicines -- 4.1. Preface -- 4.2. Introduction -- 4.3. Tumor microenvironment and metastasis -- 4.4. Current trends and challenges in breast cancer treatment -- 4.5. Cancer nanomedicines -- 4.6. Magnetic nanoparticles -- 4.7. Magnetic field-induced breast tumor targeting -- 4.8. Mechanism of magnetic targeting -- 4.9. Magnetic hyperthermia in the breast cancer -- 4.10. Mechanism of hyperthermia -- 4.11. Conclusion and prospective | |
505 | 8 | |a 5. Magneto-plasmonic stimulated breast cancer nanomedicine -- 5.1. Introduction -- 5.2. Breast cancer and its causes -- 5.3. Existing breast cancer therapies -- 5.4. Nanomaterial aspect of breast cancer therapy -- 5.5. Mechanism of cellular uptake and accumulation of NPs in tumors -- 5.6. Current status of clinical trials of nanomedicine based on MHT and PTT -- 5.7. Toxicity of nanomaterials -- 5.8. Conclusion | |
505 | 8 | |a 6. Radiation and ultrasound stimulated breast cancer nanomedicine -- 6.1. Introduction -- 6.2. Radiation therapy -- 6.3. Ultrasound therapy -- 6.4. Toxicity concerns -- 6.5. Conclusion | |
505 | 8 | |a 7. Radiotherapy and breast cancer nanomedicine -- 7.1. Radiotherapy -- 7.2. Cancers and their staging based treatment modality -- 7.3. Cancer nanomedicine -- 7.4. Breast cancer -- 7.5. Breast cancer nanomedicine -- 7.6. Conclusion | |
505 | 8 | |a 8. Ionizing radiation stimulated breast cancer nanomedicine -- 8.1. Introduction -- 8.2. X-rays and γ-rays radiation therapy -- 8.3. Nanomaterials delivering radioisotope for internal radioisotope therapy -- 8.4. Combined therapy -- 8.5. Conclusions | |
505 | 8 | |a 9. Strengths and limitations of physical stimulus in breast cancer nanomedicine -- 9.1. Introduction -- 9.2. Nanomedicine for tumor targeting -- 9.3. Stimuli responsive/triggered nanomedicine for cancer theranostics -- 9.4. Strengths and limitations of physical stimulus in breast cancer nanomedicine -- 9.5. Discussion and general comment | |
505 | 8 | |a 10. Pharmacokinetics of nanomedicine for breast cancer -- 10.1. Introduction -- 10.2. Nanobiotechnology-based platforms for breast cancer therapy -- 10.3. Types of nanoformulations (nanomedicines) for breast cancer therapy -- 10.4. Physicochemical properties of nanomedicines and their effects in pharmacokinetics and pharmacodynamics -- 10.5. Selection criteria for nano drug delivery system -- 10.6. Arsenal for drug delivery -- 10.7. Importance of nanomedicines in pharmacokinetics of breast cancer therapy -- 10.8. Pharmacokinetics of nanomedicines for breast cancer therapy -- 10.9. Novel targeting approaches for improved pharmacokinetic and pharmacodynamic features for breast cancer therapy -- 10.10. Advantages of nanomedicine in breast cancer therapy -- 10.11. Potential pharmacokinetic benefits of nanomedicine -- 10.12. Conclusion | |
505 | 8 | |a 11. Clinical and preclinical trials of breast cancer -- 11.1. Introduction -- 11.2. Biology of breast cancer metastasis -- 11.3. Nanomaterials used for breast cancer -- 11.4. Concept of preclinical trials -- 11.5. Concept of clinical trials -- 11.6. Perspective | |
505 | 8 | |a 12. Biological systems : a challenge for physical stimulation of cancer nanomedicine -- 12.1. Introduction -- 12..2 Commonly used physical stimulators in cancer nanomedicine -- 12.3. Challenges of current cancer nanomedicine -- 12.4. Conclusions and future directions. | |
520 | 3 | |a Nano drug-delivery systems responding to cellular local stimuli, such as pH, temperature, reductive agent's activation, i.e. enzymes, could effectively provide passive-mode desirable release but fail in disease treatment following the biological rhythms of brain tumor. Undoubtedly, physical stimulation of functional hybrid nanostructures can release chemotherapeutic cargos more efficiently and could offer an alternative solution as on-demand breast-cancer theranostics. Moreover, remote physical triggering of these nanostructures is more advantageous in terms of improved therapeutics efficiency, spatial and temporal controllability over the chemically stimulated release, the lack of undesirable adverse effects and minimal cargo detachment during the in vivo delivery, etc. This book is a compilation of research development lead by expert researchers and establishes a single reference module. These novel multimodalities can be extremely potent in understanding cancer through real-time observation of drug delivery, release, and activity for non-conventional breast-cancer therapies. In this scenario, the book directly addresses, for the first time, all translational aspects and clinical perspectives of physically stimulated breast-cancer nanotheranostics from a wide-ranging and multidisciplinary perception providing unrivalled and comprehensive knowledge in the field. Part of IPEM-IOP Series in Physics and Engineering in Medicine and Biology. | |
521 | |a Graduate students, young investigators, researchers working in pharmaceutical industries and professors as well as oncologists. | ||
530 | |a Also available in print. | ||
538 | |a Mode of access: World Wide Web. | ||
538 | |a System requirements: Adobe Acrobat Reader, EPUB reader, or Kindle reader. | ||
545 | |a Dr. Nanasaheb Thorat is a Marie Curie Fellow (IF) at the Department of Biomedical Engineering at the Wroclaw University of Science and Technology, Poland and is currently serving as a Management Committee member of European Commission's Horizon 2020 Cooperation in Science and Technology (COST) Programme. Dr Thorat is an active member of various scientific societies such as European Materials Research Society (EMRS), International Magnetic Society, European Nanomedicine Society and many others. Dr. Joanna Bauer is an Assistant Professor at the Department of Biomedical Engineering at the Wroclaw University of Science and Technology, Poland and is an author and co-author of more than 90 publications, 60 conference presentations, including over 20 plenary and invited lectures. She has over seventeen years' experience in carrying out national and international scientific projects within programmes such as State Committee for Scientific Research (KBN), Deutscher Akademischer Austauschdienst (DAAD) European Social Funds (ESF), FP6, FP7 and H2020. | ||
588 | 0 | |a Title from PDF title page (viewed on October 7, 2019). | |
650 | 0 | |a Breast |x Cancer |x Treatment. | |
650 | 0 | |a Breast |x Cancer |x Diagnosis. | |
650 | 0 | |a Nanobiotechnology. | |
650 | 1 | 2 | |a Breast Neoplasms |x drug therapy. |
650 | 1 | 2 | |a Breast Neoplasms |x diagnosis. |
650 | 1 | 2 | |a Theranostic Nanomedicine. |
650 | 7 | |a Biophysics. |2 bicssc | |
650 | 7 | |a SCIENCE / Life Sciences / Biophysics. |2 bisacsh | |
700 | 1 | |a Thorat, Nanasaheb D., |e editor. | |
700 | 1 | |a Bauer, Joanna, |e editor. | |
710 | 2 | |a Institute of Physics (Great Britain), |e publisher. | |
776 | 0 | 8 | |i Print version: |z 9780750324144 |
830 | 0 | |a IOP (Series). |p Release 6. | |
830 | 0 | |a IOP expanding physics. | |
830 | 0 | |a IPEM-IOP series in physics and engineering in medicine and biology. | |
856 | 4 | 0 | |u https://iopscience.uam.elogim.com/book/978-0-7503-2416-8 |z Texto completo |