Neurological disorders and imaging physics. Volume 1, Application of multiple sclerosis /

Multiple sclerosis (MS) is a disease where the body's immune system attacks the brain and spinal cord, causing debilitating side effects that last a lifetime for those affected. Magnetic resonance imaging (MRI) has become an established tool in the diagnosis and monitoring of MS due to its abil...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Suri, Jasjit S. (Autor, Editor )
Otros Autores: Saba, Luca (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Bristol [England] (Temple Circus, Temple Way, Bristol BS1 6HG, UK) : IOP Publishing, [2020]
Colección:IOP ebooks. 2020 collection.
Temas:
Central nervous system > Magnetic resonance imaging.
Central nervous system > Diseases > Diagnosis.
Multiple sclerosis > Magnetic resonance imaging.
TECHNOLOGY & ENGINEERING / Biomedical.
Acceso en línea:Texto completo
Tabla de Contenidos:
  • 1. Magnetic resonance imaging
  • 1.1. Introduction
  • 1.2. Magnetic resonance imaging
  • 2. Computed tomography principles
  • 2.1. Basic physics of x-rays
  • 2.2. Introduction to CT
  • 2.3. CT scanner components
  • 2.4. Image acquisition
  • 2.5. Image elaboration
  • 2.6. CT generations
  • 2.7. Spiral volume scanning and multislice-CT
  • 2.8. Post-processing
  • 2.9. Contrast agents
  • 2.10. Intravenous iodinate contrast agents and contrast CT acquisition
  • 2.11. ICM : adverse events
  • 2.12. Dual-energy CT
  • 3. Functional MR applied to neurological disorders
  • 3.1. Network medicine
  • 3.2. Brain networks and graph theory
  • 3.3. fcMRI and neurological disorders
  • 3.4. fMRI as an innovative and powerful tool for the investigation of neurological disorders using network medicine
  • 3.5. Physiological basis of fMRI
  • 3.6. Data-driven analysis, resting state and task methods
  • 3.7. Connectivity evaluation in the fMRI experiment : from functional MR to functional connectivity MR
  • 3.8. Brain alterations in the Tourette study
  • 3.9. Brain alterations in HIV-HCV patients
  • 3.10. Brain alterations in gustatory stimulus processing
  • 3.11. Conclusions
  • 4. MRI spectroscopy in neurological disorders
  • 4.1. Introduction
  • 4.2. Magnetic resonance spectroscopy and hypoxic-ischemic conditions
  • 4.3. Magnetic resonance spectroscopy and neoplastic disease
  • 4.4. Magnetic resonance spectroscopy and epilepsy
  • 4.5. Magnetic resonance spectroscopy and inflammatory disease of the central nervous system
  • 4.6. Magnetic resonance spectroscopy and metabolic disorders
  • 4.7. Magnetic resonance spectroscopy and neurodegenerative disorders
  • 4.8. Conclusion and future perspectives
  • 5. High field MR and neurological disorders
  • 5.1. The rationale for high field MRI
  • 5.2. Challenges, safety issues and limitations
  • 5.3. High field applications
  • 5.4. Quantitative techniques
  • 5.5. New frontiers and future developments
  • 6. Applications of nuclear medicine in multiple sclerosis
  • 6.1. Physical and physiological considerations for a nuclear medicine study
  • 6.2. Clinical developments
  • 6.3. Demyelination
  • 6.4. Brain metabolism
  • 6.5. Conclusions
  • 7. Multiple sclerosis : clinical features
  • 7.1. Introduction
  • 7.2. Epidemiology
  • 7.3. Causes and risk factors
  • 7.4. Clinical courses
  • 7.5. Clinical features
  • 7.6. Optic neuritis
  • 7.7. Cognition
  • 7.8. Psychiatric disorders in MS
  • 7.9. Comorbidities in MS
  • 7.10. Prognosis
  • 7.11. Multiple sclerosis diagnosis
  • 7.12. Treatments
  • 7.13. DMDs
  • 7.14. Treatment of relapses
  • 7.15. Symptom management
  • 7.16. DMD efficacy : NEDA
  • 7.17. PML risk monitoring
  • 7.18. MS and quality of life
  • 7.19. Conclusions
  • 8. Volumetric analysis and atrophy in multiple sclerosis
  • 8.1. Brain atrophy
  • 8.2. Conditions associated with brain atrophy
  • 8.3. Qualitative imaging findings related to brain volume reduction
  • 8.4. Pathological bases of atrophy in MS
  • 8.5. Neurodegeneration and MS, clinical implications
  • 8.6. Brain volumes and how to calculate them
  • 8.7. Linear and regional measures
  • 8.8. Segmentation based brain volume measurement methods
  • 8.9. Image segmentation methods
  • 8.10. Registration based methods
  • 8.11. Lesion segmentation
  • 8.12. Conclusion
  • 9. MR spectroscopy in multiple sclerosis
  • 9.1. Introduction
  • 9.2. 1H-MRS in MS : general concepts
  • 9.3. Acute MS lesions
  • 9.4. Chronic MS lesions
  • 9.5. NAWM, GM and NAGM
  • 9.6. MS therapy
  • 9.7. 1H-MRS in MS : clinical practice
  • 10. MR imaging and multiple sclerosis differential diagnosis
  • 10.1. Neuromyelitis optica (NMO)
  • 10.2. Acute disseminated encephalomyelitis (ADEM)
  • 10.3. Baló's concentric sclerosis
  • 10.4. Progressive multifocal leukoencephalopathy (PML)
  • 10.5. Tumefactive demyelinating lesions (TDL) or pseudotumor.

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