Foundations of regenerative biology and medicine /

Regenerative biology and medicine is a rapidly developing field that can revolutionize medicine. It is a nexus of convergent science, drawing from chemistry, physics, mathematics and bioengineering. Foundations of Regenerative Biology and Medicine introduces the essentials of regenerative biology an...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Stocum, David L. (Autor)
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Bristol [England] (Temple Circus, Temple Way, Bristol BS1 6HG, UK) : IOP Publishing, [2018]
Colección:IOP (Series). Release 5.
IOP expanding physics.
Temas:
Regenerative medicine.
Tissue engineering.
Regenerative Medicine.
Tissue Engineering.
Biomedical engineering.
TECHNOLOGY & ENGINEERING / Biomedical.
Acceso en línea:Texto completo
Tabla de Contenidos:
  • part I. Regenerative biology. 1. Regeneration
  • 1.1. Introduction
  • 1.2. Who and what regenerates?
  • 1.3. A brief history of regenerative biology
  • 1.4. The regenerative niche
  • 1.5. Approaches to the study of regeneration
  • 1.6. Mechanisms of regeneration
  • 1.7. Transdifferentiation
  • 1.8. Regeneration by adult stem cells
  • 1.9. Some tissues use multiple mechanisms of regeneration
  • 2. Wound repair by fibrosis
  • 2.1. Fibrosis is studied primarily in skin
  • 2.2. Structure and function of skin
  • 2.3. Types of wounds
  • 2.4. Stages of repair in acute wounds
  • 2.5. Aging reduces the repair capacity of acute skin wounds
  • 2.6. Chronic wounds fail to heal
  • 2.7. Non-scarring skin repair models
  • 2.8. Comparative molecular analysis of wound repair and regeneration
  • 3. Regeneration by adult stem cells
  • 3.1. Epithelial stem cells
  • 3.2. Mesenchymal stem cells
  • 3.3. Stem cells in non-regenerating organs
  • 4. Non-stem cell regenerative mechanisms
  • 4.1. Cellular re-growth: axon regeneration
  • 4.2. Regeneration from pre-existing differentiated cells
  • 4.3. Transdifferentiation: newt lens and retina
  • 5. Appendage regeneration
  • 5.1. Limb regeneration in urodele amphibians
  • 5.2. Appendage regeneration in Xenopus
  • 5.3. Mouse digit tip regeneration
  • 5.4. Regeneration of mouse ear tissue
  • 5.5. Regeneration of deer antlers
  • 5.6. Enhancement of appendage regeneration
  • part II. Regenerative medicine. 6. Strategies of regenerative medicine
  • 6.1. Historical notes
  • 6.2. Biomimetic devices and organ transplants
  • 6.3. Pharmaceutical induction of regeneration in situ
  • 6.4. Cell transplants
  • 6.5. Biomimetic tissues
  • 7. Pharmaceutical therapies for wound repair and regeneration
  • 7.1. Skin
  • 7.2. Neural tissues
  • 7.3. Musculoskeletal tissues
  • 7.4. Cardiac muscle
  • 8. Cell transplants as regenerative therapy
  • 8.1. Skin
  • 8.2. Neural tissues
  • 8.3. Liver and pancreas
  • 8.4. Musculoskeletal tissues
  • 8.5. Cardiac tissues
  • 8.6. Hematopoietic deficiency disorders
  • 9. Biomimetic tissues and organs
  • 9.1. Skin
  • 9.2. Muscle
  • 9.3. Bone
  • 9.4. Articular cartilage
  • 9.5. Cardiovascular tissue
  • 9.6. Liver and pancreas
  • 9.7. Airways
  • 9.8. Kidney and bladder
  • 10. Into the adjacent possible
  • 10.1. Technical innovations
  • 10.2. Applications of edge technologies
  • 10.3. Bioethics in regenerative medicine
  • 10.4. Concluding statement.

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