Evolutionary dynamics : the mathematics of genes and traits /

Written for researchers and postgraduate students with a background in physics or applied mathematics and a desire to apply their skills to problems in the life sciences, this beautifully illustrated and stimulating book develops an understanding of the gene-to-trait problem in the context of evolut...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Berg, Hugo van den, 1968- (Autor)
Otros Autores: Den Berg, Hugo van, Van den Berg, Hugo, VandenBerg, Hugo
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Bristol [England] (Temple Circus, Temple Way, Bristol BS1 6HG, UK) : IOP Publishing, [2015]
Colección:IOP (Series). Release 2.
IOP expanding physics.
Temas:
Evolution (Biology) > Mathematical models.
Genetics > Mathematical models.
Biophysics.
SCIENCE / Life Sciences / Biophysics.
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Preface
  • Acknowledgements
  • 1. Introduction
  • 1.1. Of snails and snakes
  • 1.2. The three key elements
  • 1.3. Stochasticity
  • 1.4. Towards a mathematics of evolution
  • 1.5. Organization of this book
  • 2. Cell biology and molecular genetics
  • 2.1. Cellular architecture and proliferation
  • 2.2. DNA, RNA and proteins
  • 2.3. Metabolism
  • 3. Phylogeny and development
  • 3.1. Phylogenic trees
  • 3.2. Development
  • 4. Elementary evolutionary dynamics
  • 4.1. Conceptual challenges and the standard assumption
  • 4.2. Haploids
  • 4.3. Diploids
  • 4.4. Projection onto tightly linked clusters of loci
  • 4.5. Drift and fixation
  • 5. Probability and measurement
  • 5.1. Fundamental laws of probability
  • 5.2. Random variables and their distributions
  • 5.3. Expectation and variance
  • 5.4. Common distributions and their properties
  • 5.5. Measurement scales
  • 6. Statistical inference and estimation
  • 6.1. The essential ideas
  • 6.2. Justifying the likelihood ratio principle
  • 6.3. Linking alleles to traits
  • 6.4. Microarrays: the stepping down procedure
  • 6.5. Analysis of bivariate data
  • 7. Sequence, structure and function
  • 7.1. Principles of dynamic programming
  • 7.2. Sequence phylogenies
  • 7.3. Sequence alignment
  • 7.4. Deep structure
  • 7.5. From sequence to function
  • 8. Analysis of quantitative trait loci
  • 8.1. Recombinant distributions
  • 8.2. Genetic markers and mapping
  • 8.3. The number of quantitative trait loci
  • 9. Evolutionary dynamics of QTL
  • 9.1. Heritability
  • 9.2. Dynamics of the additive genetic component
  • 9.3. The persistence of sex
  • 10. Adaptive dynamics and speciation
  • 10.1. Adaptive dynamics
  • 10.2. Fisher's law for adaptive dynamics
  • 10.3. Adaptive radiations and mass extinctions
  • 11. Traits as objects of selection
  • 11.1. Regimenting traits
  • 11.2. Scope and limitations of the additive genetic model
  • 12. Fitness and optimality
  • 12.1. Evolution of protandry in butterflies
  • 12.2. Evolution of juvenility
  • 12.3. Evolution of homeostasis
  • 12.4. Fitness probes
  • Appendices.
  • A. Species, speciation and systematics
  • B. Dangerous ideas
  • C. Dynamics
  • D. Constrained optimization
  • E. Thermal physics.

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