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Dietary flavonoids interfere with cancer radiotherapy /
"In parallel with the continuous rise of cancer incidence, efficient treatment becomes an increasingly important public health concern. Radiotherapy has remained one of the most important anticancer approaches for clinical management of a variety of human tumors, as at least half of all oncolog...
| Clasificación: | Libro Electrónico |
|---|---|
| Autor principal: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
New York :
Nova Medicine & Health,
[2019]
|
| Colección: | Cancer etiology, diagnosis and treatments
|
| Temas: | |
| Acceso en línea: | Texto completo |
MARC
| LEADER | 00000cam a2200000 i 4500 | ||
|---|---|---|---|
| 001 | EBSCO_on1351443562 | ||
| 003 | OCoLC | ||
| 005 | 20231017213018.0 | ||
| 006 | m o d | ||
| 007 | cr cnu---unuuu | ||
| 008 | 221121s2019 nyua ob 001 0 eng d | ||
| 040 | |a N$T |b eng |e rda |e pn |c N$T |d N$T |d OCLCO | ||
| 020 | |a 9781536166125 |q (electronic bk.) | ||
| 020 | |a 153616612X |q (electronic bk.) | ||
| 020 | |z 9781536167801 | ||
| 020 | |z 1536167800 | ||
| 035 | |a (OCoLC)1351443562 | ||
| 050 | 4 | |a RC271.R3 |b S25 2019eb | |
| 082 | 0 | 4 | |a 616.99/40642 |2 23/eng/20221209 |
| 049 | |a UAMI | ||
| 100 | 1 | |a Sak, Katrin, |d 1975- |e author. | |
| 245 | 1 | 0 | |a Dietary flavonoids interfere with cancer radiotherapy / |c Katrin Sak. |
| 264 | 1 | |a New York : |b Nova Medicine & Health, |c [2019] | |
| 300 | |a 1 online resource (xvi, 128 pages) : |b illustrations. | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 490 | 0 | |a Cancer etiology, diagnosis and treatments | |
| 520 | |a "In parallel with the continuous rise of cancer incidence, efficient treatment becomes an increasingly important public health concern. Radiotherapy has remained one of the most important anticancer approaches for clinical management of a variety of human tumors, as at least half of all oncological patients receive this therapy at some stages of their disease. With the hope to attain greater anticancer response, the interest in using natural plant-derived products as complementary treatments to conventional radiotherapy has substantially increased in the recent years. However, the interactions between phytochemicals and ionizing radiation are not always known and can be often unpredictable. Therefore, in this book, the current findings about the combined treatments of malignant cells with radiation and flavonoids, the largest group of human dietary plant polyphenols, are described. These data show that under carefully chosen dosage-schedule regimens, certain flavonoids or their natural mixtures can behave as potent radiosensitizers, augmenting radiotherapeutic efficacy in different preclinical cancer models. Such radiosensitizing action of flavonoids can be achieved through modulation of the redox status and suppression of several cellular survival pathways activated by radiotherapy, ultimately leading to the death of malignant cells. As flavonoids can concurrently protect normal healthy cells from irradiation-induced injury and thereby minimize toxic adverse reactions, use of these plant-derived agents as complementary approach to radiotherapy might open new avenues for enhancement of clinical outcome. Therefore, combining conventional anticancer modalities with conscious intake of flavonoid supplements as adjuvant agents might be an important future strategy to boost the therapeutic success in the treatment of various human malignancies"-- |c Provided by publisher. | ||
| 504 | |a Includes bibliographical references (pages 109-119) and index. | ||
| 588 | 0 | |a Print version record. | |
| 590 | |a eBooks on EBSCOhost |b EBSCO eBook Subscription Academic Collection - Worldwide | ||
| 650 | 0 | |a Cancer |x Radiotherapy. | |
| 650 | 0 | |a Flavonoids. | |
| 650 | 2 | |a Radiation Oncology | |
| 650 | 2 | |a Flavonoids | |
| 650 | 6 | |a Cancer |x Radiothérapie. | |
| 650 | 6 | |a Flavonoïdes. | |
| 650 | 7 | |a Cancer |x Radiotherapy |2 fast | |
| 650 | 7 | |a Flavonoids |2 fast | |
| 776 | 0 | 8 | |i Print version: |a Sak, Katrin, 1975- |t Dietary flavonoids interfere with cancer radiotherapy. |d New York : Nova Medicine & Health, [2019] |z 9781536167801 |w (DLC) 2019953058 |w (OCoLC)1261768333 |
| 856 | 4 | 0 | |u https://ebsco.uam.elogim.com/login.aspx?direct=true&scope=site&db=nlebk&AN=2246038 |z Texto completo |
| 938 | |a EBSCOhost |b EBSC |n 2246038 | ||
| 994 | |a 92 |b IZTAP | ||