|
|
|
|
| LEADER |
00000cam a2200000M 4500 |
| 001 |
EBSCO_on1268682768 |
| 003 |
OCoLC |
| 005 |
20231017213018.0 |
| 006 |
m d |
| 007 |
cr ||||||||||| |
| 008 |
210922s2021 xx o ||| 0 eng d |
| 040 |
|
|
|a YDX
|b eng
|c YDX
|d N$T
|d OCLCF
|d LD0
|d SFB
|
| 019 |
|
|
|a 1388522384
|a 1396875675
|a 1397410990
|
| 020 |
|
|
|a 9814998699
|q (electronic bk.)
|
| 020 |
|
|
|a 9789814998697
|q (electronic bk.)
|
| 035 |
|
|
|a (OCoLC)1268682768
|z (OCoLC)1388522384
|z (OCoLC)1396875675
|z (OCoLC)1397410990
|
| 050 |
|
4 |
|a RS420
|
| 082 |
0 |
4 |
|a 615.19
|2 23
|
| 049 |
|
|
|a UAMI
|
| 100 |
1 |
|
|a Sehgal, Sheikh Arslan.
|
| 245 |
1 |
0 |
|a Quick guideline for computational drug design (Revised Edition) /
|c authored by Sheikh Arslan Sehgal, Rana Adnan Tahir, and Muhammad Waqas.
|
| 250 |
|
|
|a Revised edition.
|
| 264 |
|
1 |
|a Singapore :
|b Bentham Science Publishers,
|c 2021.
|
| 300 |
|
|
|a 1 online resource (126 pages) :
|b illustrations
|
| 336 |
|
|
|a text
|b txt
|2 rdacontent
|
| 337 |
|
|
|a computer
|b c
|2 rdamedia
|
| 338 |
|
|
|a online resource
|b cr
|2 rdacarrier
|
| 504 |
|
|
|a Includes bibliographical references and index.
|
| 505 |
0 |
|
|a Cover -- Title -- Copyright -- End User License Agreement -- Contents -- Foreword -- Preface -- CONSENT FOR PUBLICATION -- CONFLICT OF INTEREST -- ACKNOWLEDGEMENTS -- Dedication -- Introduction to Structural Bioinformatics -- MOTIVATION -- BIOINFORMATICS -- Bioinformatics Approaches -- Static -- Dynamic -- Structural Bioinformatics -- Software and Tools -- Open-source Bioinformatics Software -- Web Services in Bioinformatics -- Virtual Screening -- Homology Modeling -- Steps of Homology Modeling -- Accuracy -- Importance of Homology modeling -- Homology Modeling Tools -- UniProt KB -- Structure Prediction Tools -- Model Validation Tools -- Sequence Analysis Tools -- Model Visualization Tools -- Virtual Screening and Docking -- Recent Advancements in Computational Drug Design -- REFERENCES -- Protein Primary Sequence Analysis -- MOTIVATION -- PROTPARAM EXPASY -- Introduction -- Brief Instructions -- Requirements -- Input -- Sequence Submission -- RESULTS INTERPRETATION -- CONCLUSION -- LIMITATIONS OF PRIMARY SEQUENCE ANALYSES -- ProtParam Expassy -- REFERENCE -- Secondary Structure Analyses -- MOTIVATION -- SECONDARY STRUCTURE OF PROTEINS -- PROFUNC -- Brief Instructions -- Requirements -- Input -- Sequence Submission -- Accessing of Data -- LIMITATIONS OF SECONDARY STRUCTURE ANALYSES TOOLS -- ProFunc -- REFERENCES -- 3D Structure Prediction -- MOTIVATION -- STRUCTURE PREDICTION TOOLS -- PHYRE2 -- Introduction -- Brief Instructions -- Requirements -- Input -- Sequence Submission -- RESULTS INTERPRETATION (RESULTS SCREEN) -- Secondary Structure and Disorder Prediction -- Domain Analysis -- Detailed Template Information -- Alignment View -- CONCLUSION -- I-TASSER -- Introduction -- Brief Instructions -- Requirements -- Input -- Sequence Submission -- Accessing Data -- RESULTS INTERPRETATION (OUTPUT) -- Structure Prediction.
|
| 505 |
8 |
|
|a Top 10 Threading Templates Used by I-TASSER -- Top 5 Final Model Predicted by I-TASSER -- Structurally Closely Related Protein -- Ligand Binding Site -- CONCLUSION -- RaptorX -- Introduction -- Brief Instructions -- Requirements -- Input -- Sequence Submission -- Accessing Data -- RESULTS INTERPRETATION (OUTPUT) -- Input Sequence and Domain Partition -- Prediction Results -- Detailed Prediction Results -- SWISS-MODEL -- Introduction -- Brief Instructions -- Requirements -- Input -- Sequence Submission -- RESULTS INTERPRETATION (RESULTS SCREEN) -- Summary -- Templates -- Models -- CONCLUSION -- 3D-JIGSAW -- Introduction -- Brief Instructions -- Requirements -- Input -- Sequence Submission -- Accessing Data -- RESULTS INTERPRETATION -- CONCLUSION -- INTFOLD2 -- Introduction -- Brief Instructions -- Requirements -- Input -- Sequence Submission -- Accessing Data -- RESULTS INTERPRETATION (OUTPUT) -- CONCLUSION -- HHPRED -- Introduction -- Brief Instructions -- Requirements -- Input -- Sequence Submission -- Accessing Data -- RESULTS INTERPRETATION (OUTPUT) -- CONCLUSION -- M4T -- Introduction -- Brief Instructions -- Requirements -- Input -- Sequence Submission -- Accessing Data -- RESULTS INTERPRETATION (OUTPUT) -- CONCLUSION -- MODELLER -- Introduction -- Downloading and Installation -- Modeling Steps -- Searching for Structures Related to PSEN2 -- BLAST (BASIC LOCAL ALIGNMENT SEARCHING TOOL) -- Template PDB File -- Aligning PSEN2 with the Template -- Model Building -- LIMITATIONS OF STRUCTURE PREDICTION TOOLS -- Phyre2 -- I-Tasser -- RaptorX -- Swiss-model -- 3D-Jigsaw -- Intfold2 -- M4T -- Modeller -- REFERENCES -- Protein 3D Structure Assessment, Evaluation, and Validation -- MOTIVATION -- MODEL EVALUATION TOOLS -- ERRAT -- Introduction -- Brief Instructions -- Requirements -- Input -- Sequence Submission -- RESULTS INTERPRETATION (OUTPUT).
|
| 505 |
8 |
|
|a CONCLUSION -- RAMPAGE -- Introduction -- Brief Instructions -- Requirements -- Input -- Sequence Submission -- RESULTS INTERPRETATION -- CONCLUSION -- ANOLEA -- Introduction -- Brief Instructions -- Requirements -- Input -- RESULTS INTERPRETATION -- CONCLUSION -- MOL PROBITY -- Introduction -- Brief Instructions -- Requirements -- Input -- RESULTS INTERPRETATION -- CONCLUSION -- VERIFY 3D -- Introduction -- Brief Instructions -- Requirements -- Input -- Sequence Submission -- RESULTS INTERPRETATION -- CONCLUSION -- PDBSUM GENERATE -- Introduction -- Brief Instructions -- Requirements -- Input -- Sequence Submission -- Accessing Data -- RESULTS INTERPRETATION -- Output -- Customization of Plots -- LIMITATIONS OF STRUCTURE EVALUATION TOOLS ERRAT -- Rampage -- Verify3D -- Pdbsum -- REFERENCES -- Ligand-Based Computational Molecular Docking Analysis -- INTRODUCTION -- Brief Instruction: MOE (Molecular Operating Environment) -- REFERENCES -- Protein-Ligand Interactions -- MOTIVATION -- Molecular Operating Environment (MOE) -- Protein-Ligand Complex -- 3D Structure Visualization through MOE -- Load and Visualize the Complex -- Selection Panel -- Protein Active Site and Rendering -- Active Site -- Rendering -- Ribbon Panel -- Atoms Panel -- Contacts Panel -- Fog and ZClip -- Molecular Surfaces and Maps -- 2D Ligand Interaction Diagram -- Rendering and Export Image -- REFERENCE -- Subject Index -- Back Cover.
|
| 590 |
|
|
|a eBooks on EBSCOhost
|b EBSCO eBook Subscription Academic Collection - Worldwide
|
| 650 |
|
0 |
|a Drugs
|x Design.
|
| 650 |
|
7 |
|a Drugs
|x Design.
|2 fast
|0 (OCoLC)fst00898790
|
| 650 |
|
2 |
|a Drug Design.
|
| 650 |
|
2 |
|a Computer-Aided Design.
|
| 700 |
1 |
|
|a Tahir, Rana Adnan.
|
| 700 |
1 |
|
|a Waqas, Muhammad.
|
| 776 |
|
|
|z 981-4998-70-2
|
| 856 |
4 |
0 |
|u https://ebsco.uam.elogim.com/login.aspx?direct=true&scope=site&db=nlebk&AN=3038287
|z Texto completo
|
| 938 |
|
|
|a YBP Library Services
|b YANK
|n 302467145
|
| 938 |
|
|
|a EBSCOhost
|b EBSC
|n 3038287
|
| 994 |
|
|
|a 92
|b IZTAP
|
