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Mesothelioma : risk factors, treatment and prognosis /
"Mesothelioma is a type of cancer in which tumors form in the tissue that lines the lungs, heart, stomach, and other organs. While mesothelioma is relatively rare, it represents a serious health crisis as the disease is aggressive and often fatal. This book includes five chapters that detail th...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
New York :
Nova Science Publishers,
[2021]
|
| Colección: | Cancer etiology, diagnosis and treatments
|
| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Intro
- Contents
- Preface
- Chapter 1
- Mesothelioma: The Advent of Immunotherapy
- Abstract
- Introduction
- Rationale: Immune Cells Orchestra inside Mesothelioma Tumor Microenvironment
- Immune Check-Point Inhibitors
- Brief History of Immunotherapy in Malignant Pleural Mesothelioma
- Advent of Immune Checkpoint Inhibitors
- Checkpoint Inhibitor within the Salvage Setting
- Anti-CTLA4
- Anti-PD1
- Anti PD-L1
- Combination of Checkpoint Inhibitors
- Checkpoint Inhibitors within the First-Line Setting
- Combination of Checkpoint Inhibitors
- Other Immunotherapies
- Vaccines
- Cellular Immunotherapy
- Conclusion
- References
- Chapter 2
- Malignant Mesothelioma
- Abstract
- Introduction
- Risk Factors
- Asbestos
- People Most at Risk of an Asbestos-Related Disease
- Non-Occupational Exposure
- Histopathology and Pathophysiology
- Presentation
- Evaluation
- Treatment
- Preventive Measures
- Curative Measures
- Surgical
- Malignant Mesothelioma of Tunica Vaginalis
- Malignant Pleural Mesothelioma
- Chemotherapy
- Radiotherapy
- Recommendation
- Targeted Therapy
- Gene Therapy
- Photodynamic Therapy
- Immunotherapy
- Virus Therapies
- Prognosis
- References
- Chapter 3
- Inflammatory and Immunological Aspects in the Surgical Management of Malignant Pleural Mesothelioma
- Abstract
- Introduction
- Prognostic Role of Inflammatory and Immunological Markers
- Blood
- Platelets Count
- White Blood Cell Count
- White Blood Cell Differential
- Hemoglobin
- Red Cell Distribution Width (RDW)
- Ratios
- Neutrophil-to-Lymphocyte Ratio
- Platelet-to-Lymphocyte Ratio
- Lymphocyte-to-Monocyte Ratio (LMR)
- Osteopontin (OPN)
- Prognostic Groups
- Cancer and Leukemia Group B
- European Organization for Research and Treatment of Cancer (EORTC)
- Modified Glasgow Prognostic Score (mGPS).
- Prognostic Risk Classification (PRC)
- Effects of Inflammation on Quality of Life
- Surgery Related Inflammatory and Immune Impairment in Cancer
- Conclusion
- References
- Biographical Sketch
- Chapter 4
- New Developments in Mesothelioma Markers
- Abstract
- Introduction
- Malignant Mesothelioma
- Asbestos
- Cancer Markers
- Biochemical Indicators Linked to Cancer Development
- Cancer Markers in Malignant Mesothelioma
- Immunochemical Markers
- Genetic Markers
- Soluble Markers of Mesothelioma
- Mesothelin
- Fibulin-3
- Osteopontin and RANTES
- New Biomarkers
- Epigenetics and miRNA
- Conclusion
- References
- Chapter 5
- Surgical Approaches to Pleural Tumours
- Abstract
- Introduction
- Benign Tumours
- Clinical Presentation
- Diagnosis
- Therapy
- Malignant Tumours
- Epidemiology and Aetiology
- Exposure to Asbestos
- Other Risk Factors
- Clinical Presentation
- Diagnosis
- Chest X-Ray
- Chest CT Scan with Contrast Enhancement
- 18-Fluorodeoxyglucose Positron Emission Tomography with (18FDG-PET)
- Magnetic Resonance Imaging (MRI)
- Other Radiological Methods
- Tumour Marker Evaluation in Pleural Fluid
- Cytological Examination of Pleural Fluid
- Pathological Anatomy
- Prognosis and Staging
- Treatment
- References
- Index
- Blank Page.