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Mesothelioma : risk factors, treatment and prognosis /

"Mesothelioma is a type of cancer in which tumors form in the tissue that lines the lungs, heart, stomach, and other organs. While mesothelioma is relatively rare, it represents a serious health crisis as the disease is aggressive and often fatal. This book includes five chapters that detail th...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Martin, Albert K. (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: New York : Nova Science Publishers, [2021]
Colección:Cancer etiology, diagnosis and treatments
Temas:
Acceso en línea:Texto completo

MARC

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245 0 0 |a Mesothelioma :  |b risk factors, treatment and prognosis /  |c Albert K. Martin, editor. 
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264 1 |a New York :  |b Nova Science Publishers,  |c [2021] 
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490 0 |a Cancer etiology, diagnosis and treatments 
504 |a Includes bibliographical references and index. 
520 |a "Mesothelioma is a type of cancer in which tumors form in the tissue that lines the lungs, heart, stomach, and other organs. While mesothelioma is relatively rare, it represents a serious health crisis as the disease is aggressive and often fatal. This book includes five chapters that detail the treatment and prognosis of the disease as well as the factors that put a person at risk for developing mesothelioma. Chapter One describes the most promising emerging immunotherapy combinations for the treatment of malignant pleural mesothelioma, discussing the biological rational underlying their development as well as the issues surrounding their clinical development. Chapter Two provides an overview of malignant mesothelioma, describing the history of its diagnosis and treatment as well as the role that asbestos exposure and other factors play in its development. Chapter Three revises the role of the main inflammatory and immunological markers as prognostic indicators in malignant pleural mesothelioma and discusses the surgical effects on immune response against cancer. Chapter Four explores the main cancer markers utilized for mesothelioma diagnosis as well as the new developments in the field. Lastly, Chapter Five examines the various surgical options available for removing pleural tumors"--  |c Provided by publisher. 
588 |a Description based on print version record and CIP data provided by publisher; resource not viewed. 
505 0 |a Intro -- Contents -- Preface -- Chapter 1 -- Mesothelioma: The Advent of Immunotherapy -- Abstract -- Introduction -- Rationale: Immune Cells Orchestra inside Mesothelioma Tumor Microenvironment -- Immune Check-Point Inhibitors -- Brief History of Immunotherapy in Malignant Pleural Mesothelioma -- Advent of Immune Checkpoint Inhibitors -- Checkpoint Inhibitor within the Salvage Setting -- Anti-CTLA4 -- Anti-PD1 -- Anti PD-L1 -- Combination of Checkpoint Inhibitors -- Checkpoint Inhibitors within the First-Line Setting -- Combination of Checkpoint Inhibitors -- Other Immunotherapies -- Vaccines -- Cellular Immunotherapy -- Conclusion -- References -- Chapter 2 -- Malignant Mesothelioma -- Abstract -- Introduction -- Risk Factors -- Asbestos -- People Most at Risk of an Asbestos-Related Disease -- Non-Occupational Exposure -- Histopathology and Pathophysiology -- Presentation -- Evaluation -- Treatment -- Preventive Measures -- Curative Measures -- Surgical -- Malignant Mesothelioma of Tunica Vaginalis -- Malignant Pleural Mesothelioma -- Chemotherapy -- Radiotherapy -- Recommendation -- Targeted Therapy -- Gene Therapy -- Photodynamic Therapy -- Immunotherapy -- Virus Therapies -- Prognosis -- References -- Chapter 3 -- Inflammatory and Immunological Aspects in the Surgical Management of Malignant Pleural Mesothelioma -- Abstract -- Introduction -- Prognostic Role of Inflammatory and Immunological Markers -- Blood -- Platelets Count -- White Blood Cell Count -- White Blood Cell Differential -- Hemoglobin -- Red Cell Distribution Width (RDW) -- Ratios -- Neutrophil-to-Lymphocyte Ratio -- Platelet-to-Lymphocyte Ratio -- Lymphocyte-to-Monocyte Ratio (LMR) -- Osteopontin (OPN) -- Prognostic Groups -- Cancer and Leukemia Group B -- European Organization for Research and Treatment of Cancer (EORTC) -- Modified Glasgow Prognostic Score (mGPS). 
505 8 |a Prognostic Risk Classification (PRC) -- Effects of Inflammation on Quality of Life -- Surgery Related Inflammatory and Immune Impairment in Cancer -- Conclusion -- References -- Biographical Sketch -- Chapter 4 -- New Developments in Mesothelioma Markers -- Abstract -- Introduction -- Malignant Mesothelioma -- Asbestos -- Cancer Markers -- Biochemical Indicators Linked to Cancer Development -- Cancer Markers in Malignant Mesothelioma -- Immunochemical Markers -- Genetic Markers -- Soluble Markers of Mesothelioma -- Mesothelin -- Fibulin-3 -- Osteopontin and RANTES -- New Biomarkers -- Epigenetics and miRNA -- Conclusion -- References -- Chapter 5 -- Surgical Approaches to Pleural Tumours -- Abstract -- Introduction -- Benign Tumours -- Clinical Presentation -- Diagnosis -- Therapy -- Malignant Tumours -- Epidemiology and Aetiology -- Exposure to Asbestos -- Other Risk Factors -- Clinical Presentation -- Diagnosis -- Chest X-Ray -- Chest CT Scan with Contrast Enhancement -- 18-Fluorodeoxyglucose Positron Emission Tomography with (18FDG-PET) -- Magnetic Resonance Imaging (MRI) -- Other Radiological Methods -- Tumour Marker Evaluation in Pleural Fluid -- Cytological Examination of Pleural Fluid -- Pathological Anatomy -- Prognosis and Staging -- Treatment -- References -- Index -- Blank Page. 
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700 1 |a Martin, Albert K.,  |e editor. 
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