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EBSCO_on1256237389 |
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20231017213018.0 |
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m o d |
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cr cnu---unuuu |
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210612s2021 gw o ||| 0 eng d |
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|a EBLCP
|b eng
|c EBLCP
|d N$T
|d OCLCF
|d OCLCQ
|d OCLCO
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|a 3736964323
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|a 9783736964327
|q (electronic bk.)
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|a (OCoLC)1256237389
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|a SF959.S54
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|a 636.108965
|2 23/eng/20220829
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|a UAMI
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100 |
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|a Weber, Lisa Annabel.
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245 |
1 |
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|a In vitro and in vivo development of a topical drug for the treatment of equine skin cancer - based on naturally occurring and synthetically modified substances in plane bark
|h [electronic resource].
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260 |
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|a Göttingen :
|b Cuvillier Verlag,
|c 2021.
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300 |
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|a 1 online resource (141 p.).
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490 |
1 |
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|a Wissenschaftliche Reihe der Klinik für Pferde ;
|v v.51
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500 |
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|a Description based upon print version of record.
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|a Intro -- LIST OF ABBREVIATIONS -- SUMMARY -- ZUSAMMENFASSUNG -- 1. Introduction -- 1.1. The equine malignant melanoma -- 1.2. The equine sarcoid: an overview -- 1.3. Topical drug application -- 1.4. Naturally occurring substances in plane bark and their syntheticallymodified derivatives -- 1.5. Hypotheses and aims of the thesis -- 2. Manuscript I:Betulinic acid shows anticancer activity against equine melanoma cells andpermeates isolated equine skin in vitro -- 2.1. Supplemental data
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|a 3. Manuscript II:In vitro assessment of triterpenoids NVX-207 and betulinyl-bis-sulfamate asa topical treatment for equine skin cancer -- 4. Manuscript III:Concentration profiles and safety of topically applied betulinic acid andNVX-207 in eight healthy horses -- A randomized, blinded, placebocontrolled,crossover pilot study -- 5. Manuscript IV:Effects of topically applied betulinic acid and NVX-207 on early stageequine melanoma -- A prospective, randomized, double-blind, placebocontrolledpilot study -- 6. General discussion -- 6.1. Summarized findings -- 6.2. Interpretation of the findings
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505 |
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|a 7. Major findings and conclusions -- 8. Future perspectives -- 9. References -- Affidavit -- Acknowledgements
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590 |
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|a eBooks on EBSCOhost
|b EBSCO eBook Subscription Academic Collection - Worldwide
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650 |
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|a Horses
|x Diseases.
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650 |
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|8 7\p
|a Skin
|x Cancer.
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650 |
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|8 8\p
|a Bark.
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650 |
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6 |
|a Chevaux
|x Maladies.
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650 |
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|a Peau
|x Cancer.
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650 |
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|a Écorce.
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650 |
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7 |
|a bark (plant material)
|2 aat
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650 |
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7 |
|a Bark
|2 fast
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650 |
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|a Horses
|x Diseases
|2 fast
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650 |
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7 |
|a Skin
|x Cancer
|2 fast
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776 |
0 |
8 |
|i Print version:
|a Weber, Lisa Annabel
|t In vitro and in vivo development of a topical drug for the treatment of equine skin cancer - based on naturally occurring and synthetically modified substances in plane bark
|d Göttingen : Cuvillier Verlag,c2021
|z 9783736974326
|
830 |
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0 |
|a Wissenschaftliche Reihe der Klinik für Pferde.
|
856 |
4 |
0 |
|u https://ebsco.uam.elogim.com/login.aspx?direct=true&scope=site&db=nlebk&AN=2942402
|z Texto completo
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938 |
|
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|a ProQuest Ebook Central
|b EBLB
|n EBL6636881
|
938 |
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|a EBSCOhost
|b EBSC
|n 2942402
|
994 |
|
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|a 92
|b IZTAP
|