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Immunotherapy

Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Sripathi, Shiv Sanjeevi
Otros Autores: Subramaniam, Raghu
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Ashland : Delve Publishing, 2020.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Cover
  • Copyright
  • DECLARATION
  • ABOUT THE EDITORS
  • TABLE OF CONTENTS
  • List of Contributors
  • List of Abbreviations
  • Preface
  • Chapter 1 History of Immunotherapy
  • 1.1 Introduction
  • 1.2 Immune System
  • 1.3 Therapies based on Anti-bodies
  • 1.4 Immunosuppression and reduction in treatment
  • 1.5 Cancer Vaccines
  • 1.6 Using viruses to heal
  • 1.7 Final points
  • 1.8 References
  • Chapter 2 Immunotherapy: Looking at the Details
  • 2.1 The basics
  • 2.2 Overview of Immunotherapy
  • 2.3 Antibodies and Tumor-specific monoclonal antibodies (mAbs)
  • 2.4 Cytokines for Treatment
  • 2.5 Oncolytic Viruses
  • 2.6 Dendritic Cells and Immunotherapy
  • 2.7 PRR Agonists
  • 2.8 Immune Checkpoint Inhibitors:
  • 2.9 Vaccines
  • 2.10 Adoptive Cell Transfer (ACT) Strategies
  • 2.11 Other Approaches
  • 2.12 Summary
  • 2.13 References
  • Chapter 3 Summarizing The Challenges and Solutions
  • 3.1 Looking at Consistenc
  • 3.2 Identification of Clinically Significant Biomarkers
  • the Inherent Difficulties
  • 3.3 Requirement for an Increased Number of Predictive Biomarkers
  • 3.4 Efficacy being Impeded by Tumor Heterogeneity
  • 3.5 Resistance to Drug Treatment
  • Development
  • 3.6 Efficacy Evaluation Needs Distinct Clinical Study Designs
  • 3.7 Cancer Immunotherapy Drugs
  • An Expensive Proposition
  • 3.8 The Challenges and Solutions
  • 3.9 The way Ahead
  • 3.10 References
  • Chapter 4 Extracorporeal Photo-Immunotherapy for Circulating Tumor Cells
  • Abstract
  • Introduction
  • Materials and Methods
  • Results
  • Discussion
  • References
  • Chapter 5 A Platform for Designing Genome-Based Personalized Immunotherapy or Vaccine against Cancer
  • Abstract
  • Introduction
  • Results
  • Discussion
  • Conclusion
  • Methods
  • References
  • Chapter 6 Immunotherapy In Gastrointestinal Cancers
  • Abstract
  • Gastrointestinal Cancers: Where Do We Stand?
  • The Rationale For Immunotherapy In Gi Cancers
  • Immunotherapeutic Strategies: A General Overview
  • Focus On Gastric, Esophageal, and Pancreatic Cancers
  • Focus on Colorectal Cancer
  • Focus on Hepatocellular Carcinoma
  • Possible Biomarkers For Immunotherapy: The Pathologist Perspective
  • Back To The Bench: Biomarkers And Genetic Signatures as Predictive Factors
  • Future Perspectives
  • References
  • Chapter 7 Harnessing the Microbiome to Enhance Cancer Immunotherapy
  • Abstract
  • Introduction
  • Coley's Toxin In Tumor Immunotherapy
  • Commensal Microflora Regulates The Innate and Adaptive Immune System
  • Toll-Like Receptors in Cancer Immunotherapy
  • Tlr Expression on T Cells and Cancer Cells
  • Vaccines Promote Weak T Cell-Mediated Tumor Regression
  • Act Therapy: A Promising Cancer Treatment
  • Lymphodepletion Augments Act Therapy
  • Mechanisms Of Tbi Effectiveness: Sinks, Suppressors, and Microbial Activators
  • Lymphodepletion Activates The Innate Immune System
  • Mimicking Tbi: Promoting The Benefits While Removing The Harm