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Exercises in Organic Synthesis Based on Synthetic Drugs

Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Souza, Marcus Vinícius de, 1979-
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Singapore : Bentham Science Publishers, 2020.
Temas:
Acceso en línea:Texto completo

MARC

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100 1 |a Souza, Marcus Vinícius de,  |d 1979- 
245 1 0 |a Exercises in Organic Synthesis Based on Synthetic Drugs  |h [electronic resource]. 
260 |a Singapore :  |b Bentham Science Publishers,  |c 2020. 
300 |a 1 online resource (250 p.) 
500 |a Description based upon print version of record. 
505 0 |a Cover -- Title -- Copyright -- End User License Agreement -- Contents -- Preface -- CONSENT FOR PUBLICATION -- CONFLICT OF INTEREST -- ACKNOWLEDGEMENTS -- How to Build a Drug: Exercises Based on the Concept of Retrosynthetic Analysis -- INTRODUCTION -- PROTECTIVE GROUPS -- EXERCISES 1 TO 4 -- RETROSYNTHETIC ANALYSIS -- EXERCISE 1 -- TWO SYNTHONS = DRUG -- Example -- Answer -- EXERCISES -- Answers -- EXERCISE 2 -- EPOXIDES -- Example -- Answer -- EXERCISES -- Answers -- EXERCISE 3 -- PIPERAZINE AND RELATED SUBSTANCES -- Examples -- Answers -- EXERCISES -- Answers -- EXERCISE 4 -- ALDEHYDES 
505 8 |a Examples -- Answers -- EXERCISES -- Answers -- CONCLUSION OF THE EXERCISES 1 TO 4 (RETROSYNTHETIC ANALYSIS) -- Organizing Synthetic Routes and Identifying Reagents -- EXERCISES 5 TO 8 -- INTRODUCTION -- EXERCISE 5 -- ORGANIZING SYNTHETIC ROUTES -- Example -- Answer -- EXERCISES -- RUTHENIUM AND ITS COMPLEXES AS OXIDANTS -- MECHANISM OF WITTIG-HORNER REACTION -- EXERCISE 6 -- IDENTIFYING REAGENTS -- Example -- Answer -- EXERCISES -- Answers -- CONCLUSION OF THE EXERCISES 5 AND 6 (ORGANIZING SYNTHETIC ROUTES AND IDENTIFYING REAGENTS) -- Identifying Drug Structure and Completing the Gaps 
505 8 |a EXERCISE 7 -- IDENTIFYING DRUG STRUCTURE -- Examples -- Answers -- EXERCISES -- Answers -- EXERCISE 8 -- COMPLETING THE GAPS -- Example -- Answer -- EXERCISES -- Answers -- CONCLUSION OF EXERCISES 7 AND 8 (IDENTIFYING DRUG STRUCTURE AND COMPLETING THE GAPS) -- BIBLIOGRAPHIC DATA OF EXERCISES 1 TO 9 -- Heteroaromatic Substances -- FIVE-MEMBERED RINGS -- SIX-MEMBERED RINGS -- FUSED SYSTEMS -- Example -- Answer -- MECHANISM OF REACTION -- EXERCISES -- Answers -- CONCLUSION -- Hydrazine and its Derivatives -- INTRODUCTION -- Example -- Answer -- EXERCISES -- Answers -- CONCLUSION -- Nitriles 
505 8 |a INTRODUCTION -- Example -- Answer -- EXERCISES -- Answers -- CONCLUSION -- Combinatorial Chemistry -- INTRODUCTION -- Example -- Answer -- MECHANISM OF REACTION -- EXERCISES -- Answers -- CONCLUSION -- REFERENCE -- Multicomponent Reaction (MCR) -- INTRODUCTION -- Example -- Answer -- Important Note -- EXERCISES -- Answers -- CONCLUSION -- Click Chemistry -- INTRODUCTION -- Example -- Answer -- EXERCISES -- Answers -- CONCLUSION -- SUGGESTIONS FOR READING -- Fluorine in Drug Discovery -- INTRODUCTION -- FLUORINATION REAGENTS 
505 8 |a Nucleophilic Fluorination for the Introduction of Fluorine Atom NaF, KF, HF, and Bu4NF -- Diethylaminosulfur Trifluoride (DAST) -- Nucleophilic Fluorination for the Introduction of the Trifluoromethyl Group -- Eletrophilic Fluorination for the Introduction of Fluorine Atoms -- Electrophilic Fluorination for the Introduction of the Trifluoromethyl Group -- Radical Fluorination -- CLASSICAL EXAMPLES OF THE IMPORTANCE OF FLUORINE IN DRUG DEVELOPMENT -- Fluoroquinolone -- Sitagliptin -- Odanacatib -- Celecoxib -- Example -- Answer -- EXERCISES -- Answers -- CONCLUSION -- REFERENCES 
500 |a List of Journals. 
590 |a eBooks on EBSCOhost  |b EBSCO eBook Subscription Academic Collection - Worldwide 
650 0 |a Organic compounds  |x Synthesis. 
650 6 |a Composés organiques  |x Synthèse. 
650 7 |a Organic compounds  |x Synthesis  |2 fast 
776 0 8 |i Print version:  |a Nora, Marcus Vinícius  |t Exercises in Organic Synthesis Based on Synthetic Drugs  |d Singapore : Bentham Science Publishers,c2020  |z 9789811487545 
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