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Frontiers in Anti-Infective Drug Discovery

This book series brings updated reviews to readers interested in advances in the development of anti-infective drug design and discovery. The scope of the book series covers a range of topics including rational drug design and drug discovery, medicinal chemistry, in-silico drug design, combinatorial...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Atta-ur-Rahman
Otros Autores: Choudhary, M. Iqbal
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Singapore : Bentham Science Publishers, 2020.
Colección:Frontiers in Anti-Infective Drug Discovery Ser.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Cover
  • Title
  • Copyright
  • End User License Agreement
  • Contents
  • Preface
  • List of Contributors
  • Eradication of Helicobacter pylori Infection with Non-Bismuth Quadruple Concomitant Therapy
  • Javier P. Gisbert* and Adrian G. McNicholl
  • INTRODUCTION
  • OBJECTIVE
  • BIBLIOGRAPHICAL SEARCHES
  • EFFICACY OF THE CONCOMITANT REGIMEN
  • COMPARISON BETWEEN CONCOMITANT AND STANDARD TRIPLE REGIMEN
  • COMPARISON BETWEEN CONCOMITANT AND SEQUENTIAL REGIMENS
  • EFFECTS OF DIFFERENT VARIABLES ON THE EFFICACY OF CONCOMITANT THERAPY
  • Clarithromycin Resistance
  • Nitroimidazole Resistance
  • Dual Clarithromycin and Metronidazole Resistance
  • Duration of Treatment
  • HOW COULD WE EVEN INCREASE THE EFFICACY OF THE CONCOMITANT TREATMENT?
  • WHAT ARE THE RESULTS WITH THE CONCOMITANT TREATMENT IN CLINICAL PRACTICE? THE EXPERIENCE OF THE EUROPEAN REGISTRY ON H. PYLORI MANAGEMENT
  • CONCLUSIONS
  • CONSENT FOR PUBLICATION
  • CONFLICT OF INTEREST
  • ACKNOWLEDGEMENTS
  • REFERENCES
  • Drug Discovery Strategies Against Emerging Coronaviruses: A Global Threat
  • Paulo Fernando da Silva Santos-Júnior1, Igor José dos Santos Nascimento1, Thiago Mendonça de Aquino1, João Xavier de Araújo-Júnior2 and Edeildo Ferreira da Silva-Júnior1,2,*
  • INTRODUCTION
  • BIOLOGICAL ASPECTS, SIGNS/SYMPTOMS AND DIAGNOSIS FOR MERS-COV, SARS-COV, AND SARS-COV-2
  • STRATEGIES USED FOR DISCOVERING NEW POTENTIAL DRUGS
  • Natural Source
  • Classical Methods Applied for Discovering New Antiviral Agents
  • Virtual Screening and Computational Techniques for Designing New Antiviral Agents
  • Drug Repurposing
  • High-Throughput Screening (HTS) for Discovering New Antiviral Agents
  • Case Study 4: Mycobacterium Tuberculosis (Mtb)
  • Pantothenate Synthetase (PanC)
  • Mtb Transcriptional Repressor (EthR)
  • Mycocyclosin Synthase (CYP121)
  • Fructose 1,6-bisphosphate Aldolase (FBA)
  • RECENT ADVANCES IN FBDD
  • CONCLUSION
  • CONSENT FOR PUBLICATION
  • CONFLICT OF INTEREST
  • ACKNOWLEDGEMENTS
  • REFERENCES
  • Phage Therapy as a Tool for Control of Foodborne Diseases: Advantages and Limitations
  • S. Pacios-Michelena1,2, R. Rodríguez-Herrera1, A. C. Flores-Gallegos1, M.L Chávez González2, E.P. Segura-Ceniceros2, R. Ramos-González3 and A. Ilyina2,*
  • INTRODUCTION
  • BACTERIOPHAGE