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Long Non-Coding RNA : From Disease Biomarkers to Targeted Therapeutics /

Long non-coding RNAs (LncRNAs) were originally regarded as ""noise"" in the genome due to their lack of protein-encoding capacity. However, their roles are now understood to cover various biological functions like gene regulation, cell proliferation, survival, differentiation, an...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Ahmad, Syed Mudasir (Editor ), Ganai, Nazir Ahmad
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Newcastle upon Tyne : Cambridge Scholars Publisher, 2020.
Temas:
Acceso en línea:Texto completo

MARC

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520 |a Long non-coding RNAs (LncRNAs) were originally regarded as ""noise"" in the genome due to their lack of protein-encoding capacity. However, their roles are now understood to cover various biological functions like gene regulation, cell proliferation, survival, differentiation, and chromatin remodeling. As an emerging group of non-coding RNA molecules, LncRNAs are involved in diverse diseases like cancer, cardiovascular, autoimmune, hormonal disorders, neurodegeneration, and infection, among others. However, knowledge of the mechanisms by which they act is still ambiguous. As such, this book me 
588 0 |a Online resource; title from digital title page (viewed on December 22, 2020). 
505 0 |a Functional aspects of long non-coding RNAs: a review -- Cancer development an therapy resistance: spotlight on the dark side of the genome -- Long non-coding RNAs in multiple sclerosis: an update -- Long non-coding RNAs in infection and immunity -- LncRNAs as important mediators for diagnosis, prognosis, and potential therapeutics in leukemias, Hepatocellular carcinoma, and breast cancer -- Long non-coding RNA in neurological diseases: a mechanistic insight -- Diverse functions of long non-coding RNAs in cardiovascular disease -- Regulatory mechanisms of long non-coding RNA's in host-pathogen. 
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