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151116s2016 nyua ob 001 0 eng |
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|a UAMI
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| 245 |
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|a Myelodysplastic syndromes (MDS) :
|b risk factors, treatment and prognosis /
|c Deanna Rodgers, editor.
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| 264 |
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1 |
|a New York :
|b Nova Biomedical,
|c [2016]
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| 300 |
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|a 1 online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 347 |
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|a data file
|2 rda
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| 490 |
1 |
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|a Recent advances in hematology research
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| 504 |
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|a Includes bibliographical references and index.
|
| 588 |
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|a Description based on print version record.
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| 505 |
0 |
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|a MYELODYSPLASTIC SYNDROMES (MDS) RISK FACTORS, TREATMENT AND PROGNOSIS ; MYELODYSPLASTIC SYNDROMES (MDS) RISK FACTORS, TREATMENT AND PROGNOSIS ; Library of Congress Cataloging-in-Publication Data; CONTENTS; PREFACE ; Chapter 1 FROM RISK FACTORS TO PROGNOSIS IN MYELODYSPLASIC SYNDROMES: THE ROLE OF GENETIC VARIANCE ; ABSTRACT ; DEFINITION AND EPIDEMIOLOGY ; ETIOLOGY AND RISK FACTORS ; PATHOPHYSIOLOGY; DIAGNOSIS, CLASSIFICATION AND PROGNOSTIC FACTORS ; TREATMENT ; PROGNOSIS ; REFERENCES ; Chapter 2 THE INFLAMMATORY AND AUTOIMMUNE NATURE OF MYELODYSPLASTIC SYNDROMES ; ABSTRACT
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| 505 |
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|a INTRODUCTIONTHE ASSOCIATION BETWEEN AUTOIMMUNE DISEASES AND MYELODYSPLASTIC SYNDROMES; T-CELL AND B-CELL ABNORMALITIES IN MDS ; THE INVOLVEMENT OF REGULATORY T-CELLS (TREG) IN THE MDS PATHOGENESIS; NATURAL KILLER CELLS IN MDS ; ABNORMAL LEVELS OF INFLAMMATORY CYTOKINES AND CHEMOKINES IN THE PEREIPHERAL BLOOD AND BONE MARROW OF MDS PATIENTS; TOLL-LIKE RECEPTOR SIGNALING AND ITS ACTIVATION IN MDS ; BONE MARROW NICHE AND ITS INVOLVEMENT IN MDS; INDUCTION OF MYELODYSPLASIA BY MYELOID-DERIVED SUPPRESSOR CELLS ; ANTI-INNATE IMMUNE THERAPIES IN MDS ; CONCLUSION AND PERSPECTIVES
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| 505 |
8 |
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|a ACKNOWLEDGMENTS REFERENCES ; Chapter 3 PATHOGENESIS OF 5q- SYNDROME ; ABSTRACT ; INTRODUCTION ; THE POSSIBLE ROLE OF CANDIDATE GENES FROM CDR IN 5q- SYNDROME ; Role of SPARC in 5q- Syndrome ; RPS14 and Ribosomopathies ; The Role of miR-145 and miR-146a in the 5q- Syndrome ; The Importance of p53 in the Molecular Mechanism of 5q- Syndrome ; Activation of p53 by Ribosome Dysfunction in Model Systems ; Activation of p53 and up-Regulation of the p53 Pathway in 5q- Syndrome ; The Relation between p53 and miR145 ; ROLE OF FURTHER GENES IN 5q- SYNDROME
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| 505 |
8 |
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|a The Role of Genes Positioned on 5q Chromosome The Role of Genes Not Positioned on Chromosome 5 ; Therapy of 5q- Syndrome ; CONCLUSION AND PERSPECTIVES; ACKNOWLEDGMENTS ; REFERENCES ; Chapter 4 GENETIC MUTATIONS IDENTIFIED IN MYELODYSPLASTIC SYNDROMES AND THEIR SIGNIFICANCE ; ABSTRACT; INTRODUCTION; MUTATIONS IN EPIGENETIC REGULATORS IN MDS; MUTATIONS OF THE DNMT3A GENE ; MUTATIONS OF THE TET2 GENE ; MUTATIONS OF THE IDH1 AND IDH2 GENES ; MUTATIONS OF THE EZH2 GENE; MUTATIONS OF THE UTX GENE ; MUTATIONS OF THE ASXL1 GENE ; MUTATIONS OF THE C-CBL GENE ; RUNX1 MUTATIONS
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| 505 |
8 |
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|a RAS MUTATIONS IN MDS TP53 MUTATIONS ; MUTATIONS IN RNA SPLICING MACHINERY ; MUTATIONS IN OTHER GENES IN MDS PATIENTS ; CONCLUSION AND PERSPECTIVES ; ACKNOWLEDGMENTS; REFERENCES ; Chapter 5 RISK FACTORS AND PROGNOSTIC SCORING SYSTEMS IN ARGENTINEAN PATIENTS WITH MDS: A MULTICENTRIC STUDY; ABSTRACT ; INTRODUCTION ; PROGNOSTIC FACTORS; BM Blasts and Cellular Morphology ; Cytogenetics ; Cytopenias ; Transfusion Dependency ; SCORING SYSTEMS ; International Prognostic Scoring System (IPSS) ; WHO CLASSIFICATION-BASED PROGNOSTIC SCORING SYSTEM (WPSS)
|
| 590 |
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|a eBooks on EBSCOhost
|b EBSCO eBook Subscription Academic Collection - Worldwide
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| 650 |
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0 |
|a Myelodysplastic syndromes
|x Treatment.
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| 650 |
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|a Myelodysplastic syndromes
|x Research.
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| 650 |
|
0 |
|a Myelodysplastic syndromes.
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| 650 |
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2 |
|a Myelodysplastic Syndromes
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| 650 |
|
6 |
|a Syndromes myélodysplasiques
|x Traitement.
|
| 650 |
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|a Syndromes myélodysplasiques
|x Recherche.
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| 650 |
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6 |
|a Syndromes myélodysplasiques.
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| 650 |
|
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|a Rodgers, Deanna,
|e editor.
|
| 776 |
0 |
8 |
|i Print version:
|t Myelodysplastic syndromes (MDS)
|d New York : Nova Biomedical, [2016]
|z 9781634843294 (paperback)
|w (DLC) 2015957369
|
| 830 |
|
0 |
|a Recent advances in hematology research series.
|
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4 |
0 |
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