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The Niakhar high-titer measles vaccine trial, 1987-1990 /

This study reports the methodology and findings of a randomized controlled vaccine trial conducted in Senegal in 1987-1990. Two high-titer measles vaccines of different strains (Edmonston-Zagreb and Schwarz) were compared with a standard vaccine (the Schwarz strain) among infants aged 5 to 10 months...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Garenne, Michel (Autor)
Otros Autores: Leroy, Odile (Contribuidor), Beau, Jean--Pierre (Contribuidor), Séne, Ibra (Contribuidor)
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Newcastle upon Tyne, UK : Cambridge Scholars Publishing, 2020.
Temas:
Acceso en línea:Texto completo

MARC

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100 1 |a Garenne, Michel,  |e author. 
245 1 4 |a The Niakhar high-titer measles vaccine trial, 1987-1990 /  |c by Michel Garenne, in collaboration with Odile Leroy, Jean-Pierre Beau, Ibra Séne, Hilton Whittle, Abdourahmane Sow. 
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504 |a Includes bibliographical references and indexes. 
588 |a Description based on print version record. 
520 |a This study reports the methodology and findings of a randomized controlled vaccine trial conducted in Senegal in 1987-1990. Two high-titer measles vaccines of different strains (Edmonston-Zagreb and Schwarz) were compared with a standard vaccine (the Schwarz strain) among infants aged 5 to 10 months. Comparison focused on clinical efficacy, immunogenicity and safety. Although both high-titer vaccines induced an immunogenic response even when given at the age of 5 months, they induced a lower level of antibodies, had more vaccine failures, and were not safe, inducing an excess mortality within. 
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650 0 |a Measles vaccine  |x History. 
650 0 |a Vaccination  |z Senegal  |x History  |y 20th century. 
650 0 |a Vaccination  |x Complications  |z Senegal  |x History  |y 20th century. 
650 0 |a Clinical trials  |z Senegal  |x History  |y 20th century. 
650 2 |a Measles Vaccine  |x history 
651 2 |a Senegal 
650 6 |a Vaccin antimorbilleux  |x Histoire. 
650 6 |a Vaccination  |z Sénégal  |x Histoire  |y 20e siècle. 
650 6 |a Vaccination  |x Complications et séquelles  |z Sénégal  |x Histoire  |y 20e siècle. 
650 6 |a Études cliniques  |z Sénégal  |x Histoire  |y 20e siècle. 
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650 7 |a Measles vaccine  |2 fast  |0 (OCoLC)fst01013172 
650 7 |a Vaccination  |2 fast  |0 (OCoLC)fst01163544 
650 7 |a Vaccination  |x Complications  |2 fast  |0 (OCoLC)fst01163545 
651 7 |a Senegal  |2 fast  |0 (OCoLC)fst01204328 
648 7 |a 1900-1999  |2 fast 
655 7 |a History  |2 fast  |0 (OCoLC)fst01411628 
700 1 |a Leroy, Odile,  |e contributor. 
700 1 |a Beau, Jean--Pierre,  |e contributor. 
700 1 |a Séne, Ibra,  |e contributor. 
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