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Golgi apparatus : structure, functions and mechanisms /

Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Hawkins, Christopher J. (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: New York : Nova Science Publishers, Inc., [2011]
Colección:Cell biology research progress.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • LIBRARY OF CONGRESS CATALOGING-IN-PUBLICATION DATA ; GOLGI APPARATUS: STRUCTURE, FUNCTIONS AND MECHANISMS ; CONTENTS ; PREFACE ; GOLGI ORGANIZATION AND STRESS SENSING ; ABSTRACT ; 1. INTRODUCTION ; 2. GOLGI STRUCTURE ; 2.a. The Intricacies of the Mammalian Golgi Apparatus ; 2.b. Golgi Ribbon Structure and Interaction with Other Organelles ; 2.c. Golgi Structure and Stacking ; 2.d. The Cytoskeleton and Maintenance of Golgi Ribbon Structure ; 2.d.1. Microtubules Maintain Golgi Ribbon Structure ; 2.d.2. The Actin Cytoskeleton and Golgi Structure.
  • 2.e. Contribution of Lipids to Golgi Structure and Function 2.e.1. Importance Of Glycerophospholipids In Golgi Structure And Function ; 2.e.2. Role of Sphingolipids and Lipid Transfer Proteins in Golgi Structure and Function ; 2.e.2.1. CERT and Stabilization of ER-Golgi Contact Sites ; 2.e.2.2. Role of FAPP2 and Transport of GlcCer Within the Golgi Apparatus ; 2.e.2.3. OSBP, Cholesterol Sensing and Maintenence of ER-Golgi Contact Sites ; 2.e.2.4. Sphingomyelin and CERT Function in Flies and Mammals ; 3. APOPTOSIS AND GOLGI STRUCTURAL ORGANIZATION.
  • 3.a. The Cellular Machinery for Apoptosis 3.b. Ceramide Mediated Apoptosis And Golgi Ribbon Architecture ; 3.b.1. Ceramide Biosynthesis and Metabolism ; 3.b.2. Ceramide Regulation and Golgi Structure ; 3.b.3. Ceramide and Apoptosis ; 4. CELLULAR LOCATION OF THE GOLGI APPARATUS IN STRESS SENSING ; CONCLUSION ; REFERENCES ; FUNCTIONAL RELATIONSHIPS BETWEEN GOLGI DYNAMICS AND LIPID METABOLISM AND TRANSPORT ; ABSTRACT ; ABBREVIATIONS ; 1. INTRODUCTION ; 2. LIPIDS AND PROTEINS INVOLVED IN MEMBRANE BUDDING ; 2.1. Adaptor/Clathrin-Coat Vesicle Formation at the Golgi.
  • 2.2. Formation of COPI Vesicles 2.3. Lipid Functions In Membrane Trafficking ; 2.3.1. PtdOH, DAG, and Lyso-Phospholipids; 2.3.1.1. PtdOH and DAG Synthesis and Interconversion ; 2.3.1.2. Roles for PtdOH and DAG in Vesicular Fission at the Golgi ; 2.3.1.3. Role of Lyso-PtdOH in Golgi Secretion ; 2.3.2. PtdIns-Polyphosphates ; 2.3.2.1. Roles of PtdInsP in Golgi Trafficking ; 2.3.2.2. PtdInsP Metabolism in the Golgi Apparatus ; 2.3.3. Cholesterol and Sphingolipids ; 2.3.3.1. Roles of the Golgi Apparatus in Cholesterol and Sphingolipid Homeostasis ; 2.3.3.2. Cholesterol Flux and Biosynthesis.
  • 2.3.3.3. Sphingolipid Biosynthesis 2.3.4. Lipid Transport Proteins Involved in Cholesterol and Sphingolipid Metabolism ; 2.3.4.1. Glycolipid Transfer by FAPP ; 2.3.4.2. Ceramide Transfer Protein ; 2.3.4.3. Golgi Cholesterol Transfer by OSBPs ; 3. PROTEINS INVOLVED IN MEMBRANE TETHERING AND FUSION ; 3.1. Vesicle Tethering at the Golgi ; 3.2. Vesicle Fusion Mediated by SNAREs ; 4. DISEASES RELATED TO LIPID METABOLISM AND GOLGI FUNCTION ; 4.1. Lowe Syndrome ; 4.2. Congenital Disorders of Glycosylation ; 4.3. Tangier Disease ; 5. CONCLUSIONS AND FUTURE DIRECTIONS ; REFERENCES.