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Current Perspectives on Anti-Infective Agents.

The volume is a comprehensive documentation on major infectious diseases from tropical countries which pose a serious threat to global healthcare programs. These include diseases such as tuberculosis, AIDS, leishmaniasis (kala-azar), elephantiasis, malaria, leprosy, various fungal disorders and emer...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Tamreihao, K., Mukherjee, Saikat, Niṃthaujama, Debānanda Esa., 1961-
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Singapore : Bentham Science Publishers, 2019.
Colección:Frontiers in Anti-Infective Agents ; volume 1.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Cover
  • Title
  • Copyright
  • End User License Agreement
  • Contents
  • Preface
  • List of Contributors
  • Prospects of Actinobacteria from Underexplored Ecosystems as Anti-infective Agents against Mycobacterium tuberculosis
  • K. Tamreihao1,2,*, Saikat Mukherjee1, Debananda S. Ningthoujam1 and Subhra Saikat Roy2
  • INTRODUCTION
  • Infection and Evolution of Drug-Resistance by M. tuberculosis
  • Perspective of Actinobacteria as Anti-TB Agents
  • Need for Exploration of Actinobacteria from Unexplored/Under-Explored Ecosystem
  • Antimycobacterial Agents from Actinobacteria Associated with Medicinal Plants
  • Antimycobacterial Agents from Actinobacteria from Other Under-Explored Ecosystems
  • CONCLUSION
  • CONSENT FOR PUBLICATION
  • CONFLICT OF INTEREST
  • ACKNOWLEDGEMENTS
  • REFERENCES
  • Protozoan and Helminth Infections: Epidemiology and Anti Infective Therapy
  • Saikat Mukherjee1,*, K. Tamreihao1, Rakhi Khunjamayum1, Khullakpam Shaheen1, Elangbam Shanta Singh1, Debananda S. Ningthoujam1 and Sumita Banerjee2
  • PROTOZOAN INFECTIONS: EPIDEMIOLOGY AND ANTI-PROTOZOAN DRUGS (SPECIAL EMPHASIS ON LEISHMANIASIS)
  • Introduction
  • Leishmaniasis
  • General Description
  • Vectors for Leishmaniasis
  • Life Cycle of Leishmania
  • Life Cycle in the Sand Fly
  • Life Cycle in the Vertebrate
  • Morphology of Leishmania
  • Morphological and Molecular Changes during Transformation of Leishmania sp.
  • Transformation from Amastigote to Promastigote
  • Transformation from Promastigote to Amastigote Form
  • Pathogenesis and Inflammation of Leishmania
  • Various Anti Leishmania Drugs Available/ Clinical Trials (Table 1)
  • Pentavalent Antimonials
  • Miltefosine
  • Pentamidine
  • Paromomycin
  • Amphotericin B
  • Sitamaquine
  • 8-aminoquinolines
  • 2-substituted Quinolines
  • Buparvaquone
  • Combination Chemotherapy
  • CONCLUDING REMARKS
  • HELMINTH INFECTIONS: EPIDEMIOLOGY AND ANTI-HELMINTHIC DRUGS (SPECIAL EMPHASIS ON ELEPHANTIASIS)
  • Introduction
  • Elephantiasis
  • Filarial Elephantiasis
  • Podoconiosis (Non Filarial Elephantiasis)
  • Anti-Elephantiasis Drugs
  • CONCLUDING REMARKS
  • CONSENT FOR PUBLICATION
  • CONFLICT OF INTEREST
  • ACKNOWLEDGEMENTS
  • REFERENCES
  • Therapeutic Drugs Used for Effective Lifelong Control of HIV and AIDS
  • Elangbam Shanta Singh1,*, Debananda S. Ningthoujam1, Laishram Jaya Devi1, Rakhi Khunjamayum1, Dollyca Ningombam2 and Laishram Somenkumar Singh3
  • INTRODUCTION
  • Types of HIV
  • Brief History of HIV and AIDS
  • Structure of HIV
  • HIV Genome and Functions of Genes
  • Structural Genes
  • gag (Group Specific Antigen) Gene
  • pol (Polymerase) Gene
  • env (Envelop Protein) Gene
  • Regulatory Genes
  • tat (Transcriptional Transactivator) Gene
  • rev Gene
  • Accessory Genes
  • Life Cycle and Mechanisms of HIV Infection
  • Routes of HIV Transmission
  • Stages of HIV Infections and Symptoms