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Pathogenic streptococci : from genomics to systems biology and control /
Streptococcus is a diverse genus of Gram-positive bacteria commonly found in multiple locations of their human and animal hosts e.g. the oral cavity and the upper respiratory tract. Many streptococci are commensals thus play a role in colonization resistance of the host. Others, however, are pathoge...
| Clasificación: | Libro Electrónico |
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| Otros Autores: | , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Norfolk, UK :
Caister Academic Press,
[2019]
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| Temas: | |
| Acceso en línea: | Texto completo |
MARC
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| 245 | 0 | 0 | |a Pathogenic streptococci : |b from genomics to systems biology and control / |c edited by Yuqing Li and Xuedong Zhou. |
| 264 | 1 | |a Norfolk, UK : |b Caister Academic Press, |c [2019] | |
| 264 | 4 | |c ©2019 | |
| 300 | |a 1 online resource | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 588 | 0 | |a Online resource; title from PDF title page (EBSCO, viewed June 6, 2019). | |
| 504 | |a Includes bibliographical references. | ||
| 520 | |a Streptococcus is a diverse genus of Gram-positive bacteria commonly found in multiple locations of their human and animal hosts e.g. the oral cavity and the upper respiratory tract. Many streptococci are commensals thus play a role in colonization resistance of the host. Others, however, are pathogenic and are responsible for a range of invasive and noninvasive diseases with high morbidity and mortality worldwide. Streptococci undergo frequent and extensive horizontal gene transfer leading to the emergence of drug resistant strains. This, combined with the current lack of effective anti-streptococcal vaccines, has led to a huge amount of research into the genomics to systems biology of these important bacteria. This timely review, edited by Yuqing Li and Xuedong Zhou, provides a comprehensive overview of the current knowledge of the most important hot-topics in streptococcal research. Topics covered include: CRISPR-Cas systems; genetic regulation by small RNAs; signal transduction by cyclic dinucleotide second messengers; the VicRK and ComDE two-component systems; mobile genetic elements; regulation of cell division; application of omics and bioinformatics tools; intrageneric and intergeneric interactions by oral streptococci; the hypervirulent M1T1 clone of GAS; Streptococcus suis; adhesion and invasion mechanisms; molecular evolution of pathogenic streptococci; novel antimicrobials; vaccine development. This volume is essential reading for everyone working with streptococci from the PhD student to the experienced scientist, in academia, the pharmaceutical or biotechnology industries and for those working in clinical environments. | ||
| 505 | 0 | |a Chapter 1. CRISPR-Cas Systems in Streptococci -- Chapter 2. Genetic Regulation of Streptococci by Small RNAs -- Chapter 3. Signal Transduction of Streptococci by Cyclic Dinucleotide Second Messengers -- Chapter 4. Mobile Genetic Elements in Streptococci -- Chapter 5. The VicRK Two-Component System Regulates Streptococcus mutans Virulence -- Chapter 6. ComDE Two-component Signal Transduction -- Systems in Oral Streptococci: Structure and Function -- Chapter 7. Regulation of Cell Division in Streptococci: Comparing with the Model Rods -- Chapter 8. Application of Omics and Bioinformatics Tools in Streptococcus Research -- Chapter 9. Intrageneric and Intergeneric Interactions Developed by Oral Streptococci: Pivotal Role in the Pathogenesis of Oral Diseases -- Chapter 10. The Emergence of Hypervirulent M1T1 Clone of Group A Streptococcus via Genetic Recombination and Host Selection -- Chapter 11. Recent Proceedings on Prevalence and Pathogenesis of Streptococcus suis -- Chapter 12. The Adhesion and Invasion Mechanisms of Streptococci -- Chapter 13. Molecular Evolution of Clinical Pathogenic Streptococci -- Chapter 14. Progress of Antimicrobial Discovery Against the Major Cariogenic Pathogen Streptococcus mutans -- Chapter 15. Recent Advances in Pathogenic Streptococcus Vaccine Development. | |
| 590 | |a eBooks on EBSCOhost |b EBSCO eBook Subscription Academic Collection - Worldwide | ||
| 650 | 0 | |a Streptococcus. | |
| 650 | 0 | |a Streptococcus |x Genetics. | |
| 650 | 2 | |a Streptococcus | |
| 650 | 6 | |a Streptococcus. | |
| 650 | 6 | |a Streptococcus |x Génétique. | |
| 650 | 7 | |a SCIENCE |x Life Sciences |x Biology. |2 bisacsh | |
| 650 | 7 | |a SCIENCE |x Life Sciences |x Microbiology. |2 bisacsh | |
| 650 | 7 | |a Streptococcus |2 fast | |
| 650 | 7 | |a Streptococcus |x Genetics |2 fast | |
| 700 | 1 | |a Li, Yuqing |c (Of Sichuan da xue), |e editor. | |
| 700 | 1 | |a Zhou, Xung, |e editor. | |
| 776 | 0 | 8 | |i Ebook version : |z 9781912530236 |
| 776 | 0 | 8 | |i Print version: |t Pathogenic streptococci. |d Norfolk, UK : Caister Academic Press, [2019] |z 1912530228 |z 9781912530229 |w (OCoLC)1102475054 |
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