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Algorithms for sample preparation with microfluidic lab-on-chip /
Recent microfluidic technologies have brought a complete paradigm shift in automating biochemical processing on a tiny lab-on-chip (a.k.a. biochip) that replaces expensive and bulky instruments traditionally used in implementing bench-top laboratory protocols. Biochips have already made a profound i...
| Clasificación: | Libro Electrónico |
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| Autores principales: | , , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Gistrup, Denmark :
River Publishers,
[2019]
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| Colección: | River Publishers series in biomedical engineering.
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| Temas: | |
| Acceso en línea: | Texto completo |
| Sumario: | Recent microfluidic technologies have brought a complete paradigm shift in automating biochemical processing on a tiny lab-on-chip (a.k.a. biochip) that replaces expensive and bulky instruments traditionally used in implementing bench-top laboratory protocols. Biochips have already made a profound impact on various application domains such as clinical diagnostics, DNA analysis, genetic engineering, and drug discovery, among others. They are capable of precisely manipulating micro-/pico-liter quantities of fluids, and provide integrated support for mixing, storage, transportation, and sensing, on-chip. In almost all bioprotocols, sample preparation plays an important role, which includes dilution and mixing of several fluids satisfying certain volumetric ratios. However, designing algorithms that minimize reactant-cost and sample-preparation time suited for microfluidic chips poses a great challenge from the perspective of protocol mapping, scheduling, and physical design. Algorithms for Sample Preparation with Microfluidic Lab-on-Chip attempts to bridge the widening gap between biologists and engineers by introducing, from the fundamentals, several state-of-the-art computer-aided-design (CAD) algorithms for sample preparation with digital and flow-based microfluidic biochips. Technical topics discussed in the book include: * Basics of digital and flow-based microfluidic lab-on-chip * Comprehensive review of state-of-the-art sample preparation algorithms * Sample-preparation algorithms for digital microfluidic lab-on-chip * Sample-preparation algorithms for flow-based microfluidic lab-on-chip. |
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| Descripción Física: | 1 online resource |
| ISBN: | 8770220549 9788770220545 9781003337157 1003337155 9781000792461 1000792463 9781000795783 1000795780 |