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|a Atta-ur-Rehman.
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|a Frontiers in Clinical Drug Research.
|n Volume 4,
|p Diabetes and Obesity
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| 260 |
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|a Sharjah :
|b Bentham Science Publishers,
|c 2019.
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| 300 |
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|a 1 online resource (280 pages)
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|a Frontiers in Clinical Drug Research - Diabetes and Obesity Ser. ;
|v v. 4
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|a Print version record.
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|a Cover; Title; Biblography; End User License Agreement; Contents; Preface; List of Contributors; Pharmacologic Obesity Treatment -- Emphasis on Efficacy and Cardiometabolic Markers; Fariha Salman1, Ivan Gerling2 and Helmut O. Steinberg*, 2; INTRODUCTION; Weight-Loss Drug Decreasing Food Absorption; Weight-Loss Drugs Decreasing Food Intake; Combination of Topiramate and Phentermine; Combination of Naltrexone and Bupropion; Liraglutide; Summary; CONSENT FOR PUBLICATION; CONFLICT OF INTEREST; ACKNOWLEDGEMENTS; REFERENCES
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| 505 |
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|a Interplay Between Bile Acid and GLP-1 Receptor Agonist Signaling Informs the Design of Drugs to Combat Obesity and its Metabolic ComplicationsJessica Felton1 and Jean-Pierre Raufman2,*; INTRODUCTION AND OVERVIEW; Bile Acid Synthesis & Circulation; Bile Acid Feedback Mechanisms; TAKEDA G PROTEIN-COUPLED RECEPTOR-5 (TGR5); TGR5 & Immunity; TGR5 in the Liver and Gallbladder; TGR5 & Thyroid Hormone Activation; GLUCAGON-LIKE PEPTIDE 1 (GLP-1); Physiology of GLP-1; Effects of GLP-1; Pathophysiology of GLP-1; THE ROLE OF TGR5 IN GLP-1 SECRETION; THE ROLE OF FXR IN GLUCOSE HOMEOSTASIS
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|a MANIPULATING THE BILE ACID POOL FOR GLUCOSE HOMEOSTASISBILE ACIDS & GLP-1 AFTER BARIATRIC SURGERY; Glucose Homeostasis following Gastric Bypass Surgery; Increased Bile Acid Levels after Gastric Bypass Surgery; PHARMACOLOGY; GLP-1 Agonists; DPP4 Inhibitors; TGR5 Agonists; FUTURE DIRECTIONS; CONCLUSIONS; CONSENT FOR PUBLICATION; CONFLICT OF INTEREST; ACKNOWLEDGEMENTS; REFERENCES; Sodium-Glucose Co-Transporters Inhibitors for Type 2 Diabetes Mellitus: The 'New Kids on the Block' in the Era of Evidence-based Medicine; Cheow Peng Ooi1,*, Norlaila Mustafa2, Nor Azmi Kamaruddin2 and Munn Sann Lye3
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|a INTRODUCTIONEpidemiology; Pathophysiology of T2DM; Glycaemic Control; NEW TREATMENT OPTION; Role of SGLTs in Glucose Homoeostasis; Drug Development Status of SGLT Inhibitors; Efficacy of SGLT2 Inhibitors; Safety of SGLT2 Inhibitors; Post-regulatory Approval and Long-term Safety Concerns; EVIDENCE-BASED MEDICINE; Evidence-based Medicine at the Crossroads; Dilemmas in Evidence-based Medicine; Restricted View of Evidence; Limitations of Clinical Trials; Misleading Results; Issues in Translating RCTs to the Clinical Care Arena; The Efficacy-Efficiency Gap; Secondary Research of Evidence Synthesis
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|a Diabetes
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|a Obesity.
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|a Obesity
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|a Obésité.
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|a Diabetes
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|a Diabetes
|x Treatment
|2 fast
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|a Obesity
|2 fast
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| 776 |
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|i Print version:
|a Atta-ur-Rehman.
|t Frontiers in Clinical Drug Research - Diabetes and Obesity.
|d Sharjah : Bentham Science Publishers, 2019
|z 9781681084459
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| 830 |
|
0 |
|a Frontiers in Clinical Drug Research - Diabetes and Obesity Ser.
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| 856 |
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|u https://ebsco.uam.elogim.com/login.aspx?direct=true&scope=site&db=nlebk&AN=2025678
|z Texto completo
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| 880 |
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|6 505-00/(S
|a The Harm of Poor-quality EvidenceCURRENT EFFORTS IN BRIDGING THE EFFICACY-EFFICIENCY GAP; FUTURE RESEARCH; CONCLUSION; CONSENT FOR PUBLICATION; CONFLICT OF INTEREST; ACKNOWLEDGEMENTS; REFERENCES; The Effects of Traditional Chinese Medicine on Inflammatory Cytokines in Diabetic Nephropathy: The Progress in the Past Decades; Xiang Tu1, YuanPing Deng2, Ming Chen3, James B. Jordan1 and Sen Zhong1,*; INTRODUCTION; MAJOR INFLAMMATORY CYTOKINES INVOLVED IN DN; Transforming Growth Factor (TGF)-β1; Tumor Necrosis Factor (TNF)-α; Monocyte Chemoattractant Protein-1 (MCP-1); Interleukin (IL)-1; IL-6
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