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Tools and Applications in Gene Therapy
| Clasificación: | Libro Electrónico |
|---|---|
| Autor principal: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Ashland :
Delve Publishing,
2019.
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| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Cover; Half Title Page; Title Page; Copyright Page; Declaration; About the Editor; Table of Contents; List of Contributors; List of Abbreviations; Preface; Chapter 1 Gene Therapy: Progress and Predictions; Abstract; Introduction; Gene Therapy Remains A Delivery Challenge; Replacement Gene Therapy Using Bone Marrow Transplantation; Direct Injection of Adeno-Associated Virus Vectors For Gene Replacement Therapy; Gene Therapy to Treat Cancer And Infectious Disease; Gene Therapy as a Different Formulation of a Conventional Medicine; Where Will Gene Therapy Be In Another 25 Years?; References
- Chapter 2 Advances In Non-Viral DNA Vectors For Gene TherapyAbstract; Introduction to Gene Therapy; Challenges of Using Plasmid Vectors For Gene Therapy; Improvements to Plasmid Vectors; Development of Minicircles and Minivectors; Therapeutic Needs Best Addressed by Minimized Vectors; Concluding Remarks: Moving Minimized Non-Viral DNA Vectors Into The Clinic; Acknowledgments; Author Contributions; References; Chapter 3 Gene Delivery Technologies For Efficient Genome Editing: Applications In Gene Therapy; Abstract; Introduction; Viral-Based Vectors; Non-Viral-Based Vectors; Acknowledgements
- Chapter 5 The Use of The Humanized Mouse Model In Gene Therapy And Immunotherapy For HIV and CancerAbstract; Introduction; Peripheral Cell-Based Immunotherapy Modeling In Humanized Mice; Stem Cell-Based Gene Therapy In Humanized Mice; PD-1 and IFN-I Blockade Therapy For HIV and Cancer; Future Directions; Author Contributions; References; Chapter 6 Innovative Therapeutic Strategies For Cystic Fibrosis: Moving Forward To CRISPR Technique; Abstract; Introduction; Genetics; Therapy; Repairing The CFTR Mutation: Gene Correction With Genome-Editing Nucleases; Conclusion; Author Contributions