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|a UAMI
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|a Pandey, Prerna.
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|a GTPases in Cellular Signalling
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|a Ashland :
|b Delve Publishing,
|c 2019.
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|a 1 online resource (236 pages)
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|a text
|b txt
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|a Cover; Half Title Page; Title Page; Copyright Page; Declaration; About the Editors; Table of Contents; List of Contributors; List of Abbreviations; Preface; Chapter 1 GTPases in Signalling: An Overview; 1.1 Introduction; 1.2 GTPases: A Glimpse; 1.3 General Characteristics of Rho GTPases; 1.4 Cellular Signaling; 1.5 Cell Migration and GTPases; 1.6 Cell Body Contraction And Tail Retraction; 1.7 Signaling Pathways That Lie Upstream And Downstream in Rho GTPases; 1.8 Activation of Rho GTPases By Adhesion; 1.9 Crosstalk Between Rho GTPases; 1.10 Altered Role In Cancer
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|a 1.11 Summarizing The Role of GTPases1.12 Summary; 1.13 References; Chapter 2 GTPases in Prokaryotes; 2.1 Rho GTPases in Bacteria; 2.2 Bacterial Toxins Manipulate Rho-GTPase and Alter Cell Barriers; 2.3 Inactivation of Toxins, Epithelial/Endothelial Barrier Permeability and Inflammatory Response by Rho GTPase; 2.4 Bacterial Virulence Factors Towards Rho GTPases; 2.5 Rho GTPases Are Targeted By Virulence Factors of Bacteria; 2.6 GTPases in Archea; 2.7 Summary; 2.8 References; Chapter 3 GTPases, Signalling and Roles in Organisms; 3.1 In Plants; 3.2 GTPases And Auxins
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|a 3.3 GTPases In Plant Stress3.4 Rho Family Of GTPases: In Development Of Neurons; 3.5 Summary; 3.6 References; Chapter 4 Rho GTPases: Signaling and Stem Cells; 4.1 Introduction; 4.2 Embryonic Stem Cells; 4.3 Pluripotency Markers; 4.4 Embryonic Stem Cell Culture; 4.5 Embryonic Stem Cells And Rho Family Gtpases; 4.6 Rho Signaling Pathways Of Embryonic Stem Cells; 4.7 Rac Signaling In ES Cells; 4.8 Cdc42 Signaling In ES Cells; 4.9 Regulation Of Rho GTPases In Hematopoietic Stem Cells; 4.10 HSCs Homing, Trafficking And Interaction; 4.11 HSC Proliferation, Survival, And Self-Renewal; 4.12 Summary
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|a 4.13 ReferencesChapter 5 GTPases As Targets for Therapy; 5.1 GTPases And Drug Targets; 5.2 Rho GTPases and Alzheimer's Disease (AD); 5.3 Rho GTPases As Targets In Other Neuronal Diseases; 5.4 Rho GTPases As Targets In Cardiovascular Diseases; 5.5 Role Of Rho GTPases In Cancer; 5.6 Summary; 5.7 References; Chapter 6 Rho GTPase Signalling in Cell Migration; Abstract; Introduction; Lamellipodium-Driven Migration; Migration In 3D And In Vivo: Different Types of Protrusions?; Filopodia And Cell Migration; Bleb-Driven Cell Migration; Collective Cell Migration; Migration Across Other Cells
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|a Conclusions And Future DirectionsAcknowledgments; References; Chapter 7 Are There Rab GTPases in Archaea?; Abstract; Introduction; Results; Discussion; Materials And Methods; Acknowledgments; References; Chapter 8 The GTPase-Activating Protein Rga1 Interacts with Rho3 GTPase and May Regulate Its Function in Polarized Growth in Budding Yeast; Abstract; Introduction; Results; Discussion; Materials And Methods; Acknowledgments; Author Contributions; References; Chapter 9 Ran GTPase-Activating Protein 1 Is a Therapeutic Target in Diffuse Large B-Cell Lymphoma; Abstract; Introduction
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|a Sanjeevi, Shiv.
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|a Pandey, Prerna.
|t GTPases in Cellular Signalling.
|d Ashland : Delve Publishing, ©2019
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